Peck, Yoshimi, Pickering, Darren, Mobli, Mehdi, Liddell, Michael J., Wilson, David T, Ruscher, Roland, Ryan, Stephanie, Buitrago, Geraldine, McHugh, Connor, Love, Nicholas C., Pinlac, Theresa, Haertlein, Michael, Kron, Michael A., Loukas, Alex, and Daly, Norelle L. (2024) Solution structure of the N-terminal extension domain of a Schistosoma japonicum asparaginyl-tRNA synthetase. Journal of Biomolecular Structure and Dynamics. (In Press)

Jamtsho, Tenzin, Yeshi, Karma, Perry, Matthew J., Loukas, Alex, and Wangchuk, Phurpa (2024) Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products. Pharmaceuticals, 17 (13). 283.

Jamtsho, Tenzin, Loukas, Alex, and Wangchuk, Phurpa (2024) Pharmaceutical Potential of Remedial Plants and Helminths for Treating Inflammatory Bowel Disease. Pharmaceuticals, 17 (7). 819.

Sikder, Suchandan, Pierce, Doris, Sarkar, Eti R., McHugh, Connor, Quinlan, Kate G.R., Giacomin, Paul, and Loukas, Alex (2024) Regulation of host metabolic health by parasitic helminths. Trends in Parasitology, 40 (5). pp. 386-400.

Wangchuk, Phurpa, Yeshi, Karma, and Loukas, Alex (2024) Ulcerative colitis: clinical biomarkers, therapeutic targets, and emerging treatments. Trends in Pharmacological Sciences, 45 (10). pp. 892-903.

Aroian, Raffi V., Loukas, Alex, and Martin, Richard J. (2023) Anthelmintics V: Drugs, resistance, and vaccines. International Journal for Parasitology, 53 (8). pp. 391-392.

Pierce, Doris R., Mcdonald, Malcolm, Merone, Leanne, Becker, Luke, Thompson, Fintan, Lewis, Chris, Ryan, Rachael Y.M., Hii, Sze Fui, Zendejas-Heredia, Patsy, Traub, Rebecca J., Field, Matthew A., Rahman, Tony, Croese, John, Loukas, Alex, McDermott, Robyn, and Giacomin, Paul R. (2023) Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes. Nature Communications, 14. 4503.

Uzoechi, Samuel C., Rosa, Bruce A., Singh, Kumar Sachin, Choi, Young Jun, Bracken, Bethany K., Brindley, Paul J., Townsend, R. Reid, Sprung, Robert, Zhan, Bin, Bottazzi, Maria Elena, Hawdon, John M., Wong, Yide, Loukas, Alex, Djuranovic, Sergej, and Mitreva, Makedonka (2023) Excretory/Secretory Proteome of Females and Males of the Hookworm Ancylostoma ceylanicum. Pathogens, 12 (1). 95.

Takjoo, Rozita, Wilson, David T., Bansal, Paramjit S., Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2023) Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1. Exploration of Drug Science, 1. pp. 172-179.

Wangchuk, Phurpa, Yeshi, Karma, and Loukas, Alex (2023) Metabolomics and lipidomics studies of parasitic helminths: molecular diversity and identification levels achieved by using different characterisation tools. Metabolomics, 19 (63).

Wong, Yide, Pearson, Mark S., Fedorova, Olga, Ivanov, Vladimir, Khmelevskaya, Ekaterina, Tedla, Bemnet, Arachchige, Buddhika Jayakody, Reed, Sarah, Field, Matt, Laha, Thewarach, Loukas, Alex, and Sotillo-Gallego, Javier (2023) Secreted and surface proteome and transcriptome of Opisthorchis felineus. Frontiers in Parasitology, 2. 1195457.

White, Ruby, Sotillo, Javier, Ancarola, María Eugenia, Borup, Anne, Boysen, Anders Toftegaard, Brindley, Paul J., Buzás, Edit I., Cavallero, Serena, Chaiyadet, Sujittra, Chalmers, Iain W., Cucher, Marcela A., Dagenais, Maude, Davis, Chelsea N., Devaney, Eileen, Duque-Correa, Maria A., Eichenberger, Ramon Marc, Fontenla, Santiago, Gasan, Thomas A., Hokke, Cornelis H., Kosanovic, Maja, Kuipers, Marije E., Laha, Thewarach, Loukas, Alex, Maizels, Rick M., Marcilla, Antonio, Mazanec, Hynek, Morphew, Russell M., Neophytou, Kyriaki, Nguyen, Linh Thuy, Nolte-‘t Hoen, Esther, Povelones, Michael, Robinson, Mark W., Rojas, Alicia, Schabussova, Irma, Smits, Hermelijn H., Sungpradit, Sivapong, Tritten, Lucienne, Whitehead, Bradley, Zakeri, Amin, Nejsum, Peter, Buck, Amy H., and Hoffmann, Karl F. (2023) Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility. Journal of Extracellular Vesicles, 12 (1). 12298.

Lennox-Bulow, Danica, Smout, Michael, Loukas, Alex, and Seymour, Jamie (2023) Stonefish (Synanceia spp.) Ichthyocrinotoxins: An ecological review and prospectus for future research and biodiscovery. Toxicon, 236. 107329.

Ruangsuwast, Apisit, Smout, Michael J., Brindley, Paul J., Loukas, Alex, Laha, Thewarach, and Chaiyadet, Sujittra (2023) Tetraspanins from the liver fluke Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production. Folia Parasitologica, 70. 017.

Khudhair, Zainab, Alhallaf, Rafid, Eichenberger, Ramon M., Field, Matt, Krause, Lutz, Sotíllo, Javier, and Loukas, Alex (2022) Administration of Hookworm Excretory/Secretory Proteins Improves Glucose Tolerance in a Mouse Model of Type 2 Diabetes. Biomolecules, 12 (5). 637.

Ritmejeryte, Edita, Ryan, Rachael Y.M., Byatt, Brendan J., Peck, Yoshimi, Yeshi, Karma, Daly, Norelle L., Zhao, Guangzu, Crayn, Darren, Loukas, Alex, Pyne, Stephen G., Ruscher, Roland, and Wangchuk, Phurpa (2022) Anti-inflammatory properties of novel galloyl glucosides isolated from the Australian tropical plant Uromyrtus metrosideros. Chemico-Biological Interactions, 368. 110124.

Mekonnen, Gebeyaw G., Tedla, Bemnet A., Pearson, Mark S., Becker, Luke, Field, Matt, Amoah, Abena S., van Dam, Govert, Corstjens, Paul L.A.M., Mduluza, Takafira, Mutapi, Francisca, Loukas, Alex, and Sotillo, Javier (2022) Characterisation of tetraspanins from Schistosoma haematobium and evaluation of their potential as novel diagnostic markers. PLoS Neglected Tropical Diseases, 16 (1). e0010151.

Shalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Toth, Istvan, and Skwarczynski, Mariusz (2022) Development of a peptide vaccine against hookworm infection: Immunogenicity, efficacy, and immune correlates of protection. Journal of Allergy and Clinical Immunology, 150 (1). 157-169.e10.

Yeshi, Karma, Ruscher, Roland, Loukas, Alex, and Wangchuk, Phurpa (2022) Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics. Frontiers in Parasitology, 1. 984152.

Chaiyadet, Sujittra, Tangkawattana, Sirikachorn, Smout, Michael J., Ittiprasert, Wannaporn, Mann, Victoria H., Deenonpoe, Raksawan, Arunsan, Patpicha, Loukas, Alex, Brindley, Paul J., and Laha, Thewarach (2022) Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini. PLoS Pathogens, 18 (9). e1010839.

Kamath, Sandip D., Liu, Tiange, Giacomin, Paul, Loukas, Alex, Navarro, Severine, and Lopata, Andreas L. (2022) Mollusk allergy: Not simply cross-reactivity with crustacean allergens. Allergy, 77 (10). pp. 3127-3130.

Langdon, Kane, Buitrago, Geraldine, Pickering, Darren, Giacomin, Paul, Loukas, Alex, and Haleagrahara, Nagaraja (2022) Na-AIP-1 secreted by human hookworms suppresses collagen-induced arthritis. Inflammopharmacology, 30 (2). pp. 527-535.

Schmidt, Casey A., Cooke, Ira, Wilson, David T., Miller, David J., Peigneur, Steve, Tytgat, Jan, Field, Matthew, Takjoo, Rozita, Smout, Michael J., Loukas, Alex, and Daly, Norelle L. (2022) Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity. Journal of Natural Products, 85 (7). pp. 1789-1798.

Loukas, Alex, Croese, John, Rees, Megan A., and McCarthy, James S. (2022) Not All Worms Were Created Equal. Frontiers in Immunology, 13. 877707.

Ryan, Stephanie M., Ruscher, Roland, Johnston, Wayne A., Pickering, Darren A., Kennedy, Malcolm W., Smith, Brian O., Jones, Linda, Buitrago, Geraldine, Field, Matt A., Esterman, Adrian J., McHugh, Connor P., Browne, Daniel J., Cooper, Martha M., Ryan, Rachael Y.M., Doolan, Denise L., Engwerda, Christian R., Miles, Kim, Mitreva, Makedonka, Croese, John, Rahman, Tony, Alexandrov, Kirill, Giacomin, Paul R., and Loukas, Alex (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119 (36). e2202795119.

Cobos, Claudia, Bansal, Paramjit S., Wilson, David T., Jones, Linda, Zhao, Guangzu, Field, Matthew A., Eichenberger, Ramon M., Pickering, Darren A., Ryan, Rachael Y.M., Ratnatunga, Champa N., Miles, John J., Ruscher, Roland, Giacomin, Paul R., Navarro, Severine, Loukas, Alex, and Daly, Norelle L. (2022) Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells. Frontiers in Medicine, 9. 934852.

De Sousa, Karina P., Potriquet, Jeremy, Mulvenna, Jason, Sotillo-Gallego, Javier, Groves, Penny L., Loukas, Alex, Apte, Simon H., and Doolan, Denise L. (2022) Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection. International Journal for Parasitology, 52 (1). pp. 35-45.

Chaiyadet, Sujittra, Sotillo, Javier, Krueajampa, Watchara, Thongsen, Sophita, Smout, Michael, Brindley, Paul J., Laha, Thewarach, and Loukas, Alex (2022) Silencing of Opisthorchis viverrini Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles. Frontiers in Cellular and Infection Microbiology, 12. 827521.

Quinzo, M.J., Perteguer, M.J., Brindley, P.J., Loukas, A., and Sotillo, J. (2022) Transgenesis in parasitic helminths: a brief history and prospects for the future. Parasites and Vectors, 15 (1). 110.

Chapman, Paul R., Llewellyn, Stacey, Jennings, Helen, Becker, Luke, Giacomin, Paul, McDougall, Rodney, Robson, Jennifer, Loukas, Alex, and McCarthy, James (2022) The production of Necator americanus larvae for use in experimental human infection. Parasites & Vectors, 15. 242.

Loukas, Alex, Maizels, Rick M., and Hotez, Peter J. (2021) The yin and yang of human soil-transmitted helminth infections. International Journal for Parasitology, 51 (13-14). pp. 1243-1253.

Brindley, Paul J., Bachini, Melinda, Ilyas, Sumera I., Khan, Shahid A., Loukas, Alex, Sirica, Alphonse E., Teh, Bin Tean, Wongkham, Sopit, and Gores, Gregory J. (2021) Cholangiocarcinoma. Nature Reviews Disease Primers, 7. 65. pp. 1-17.

Chapman, Paul R., Giacomin, Paul, Loukas, Alex, and McCarthy, James S. (2021) Experimental human hookworm infection: a narrative historical review. PLoS Neglected Tropical Diseases, 15 (12). e0009908.

Khudhair, Zainab, Alhallaf, Rafid, Eichenberger, Ramon M., Whan, Jen, Kupz, Andreas, Field, Matt, Krause, Lutz, Wilson, David T., Daly, Norelle L., Giacomin, Paul, Sotillo, Javier, and Loukas, Alex (2021) Gastrointestinal helminth infection improves insulin sensitivity, decreases systemic inflammation, and alters the composition of gut microbiota in distinct mouse models of Type 2 diabetes. Frontiers in Endocrinology, 11. 606530.

Mairiang, Eimorn, Laha, Thewarach, Kaewkes, Sasithorn, Loukas, Alex, Bethony, Jeffrey, Brindley, Paul j., and Sripa, Banchob (2021) Hepatobiliary morbidities detected by ultrasonography in Opisthorchis viverrini-infected patients before and after praziquantel treatment: a five-year follow up study. Acta Tropica, 217. 105853.

Wangchuk, Phurpa, Anderson, Dovile, Yeshi, Karma, and Loukas, Alex (2021) Identification of small molecules of the infective stage of human hookworm using LCMS-based metabolomics and lipidomics protocols. ACS Infectious Diseases, 7. pp. 3264-3276.

Ryan, Rachael Y.M., Seymour, Jamie, Loukas, Alex, Lopez, J. Alejandro, Ikonomopoulou, Maria P., and Miles, John J. (2021) Immunological responses to envenomation. Frontiers in Immunology, 12. 661082.

Pearson, Mark S., Tedla, Bemnet A., Becker, Luke, Nakajima, Rie, Jasinskas, Al, Mduluza, Takafira, Mutapi, Francisca, Oeuvray, Claude, Greco, Beatrice, Sotillo, Javier, Felgner, Philip L., and Loukas, Alex (2021) Immunomics-guided antigen discovery for praziquantel-induced vaccination in urogenital human schistosomiasis. Frontiers in Immunology, 12. 663041.

Pearson, Mark S., Tedla, Bemnet A., Mekonnen, Gebeyaw G., Proietti, Carla, Becker, Luke, Nakajima, Rie, Jasinskas, Al, Doolan, Denise L., Amoah, Abena S., Knopp, Stefanie, Rollinson, David, Ali, Said M., Kabole, Fatma, Hokke, Cornelis H., Adegnika, Akim A., Field, Matt A., van Dam, Govert, Corstjens, Paul L.A.M., Mduluza, Takafira, Mutapi, Francisca, Oeuvray, Claude, Greco, Beatrice, Chaiyadet, Sujittra, Laha, Thewarach, Cai, Pengfei, McManus, Donald P., Bottazzi, Maria Elena, Felgner, Philip L., Sotillo, Javier, and Loukas, Alex (2021) Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study. The Lancet Microbe, 2 (11). e617-e626.

Phumrattanaprapin, Wuttipong, Pearson, Mark, Pickering, Darren, Tedla, Bemnet, Smout, Michael, Chaiyadet, Sujittra, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2021) Monoclonal antibodies targeting an opisthorchis viverrini extracellular vesicle tetraspanin protect hamsters against challenge infection. Vaccines, 9 (7). 740.

Shalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Skwarczynski, Mariusz, and Toth, Istvan (2021) Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy. Vaccines, 9. 1034.

Phumrattanaprapin, Wuttipong, Chaiyadet, Sujittra, Brindley, Paul J., Pearson, Mark, Smout, Michael J., Loukas, Alex, and Laha, Thewarach (2021) Orally administered Bacillus spores expressing an extracellular vesicle-derived tetraspanin protect hamsters against challenge infection with carcinogenic human liver fluke. Journal of Infectious Diseases, 223 (8). pp. 1445-1455.

Montaño, Karen J., Loukas, Alex, and Sotillo, Javier (2021) Proteomic approaches to drive advances in helminth extracellular vesicle research. Molecular Immunology, 131. pp. 1-5.

Smallwood, Taylor B., Navarro, Severine, Cristofori-Armstrong, Ben, Watkins, Thomas S., Tungatt, Katie, Ryan, Rachael Y.M., Haigh, Oscar L., Lutzky, Viviana P., Mulvenna, Jason P., Rosengren, Karl Johan, Loukas, Alex, Miles, John J., and Clark, Richard J. (2021) Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo. Journal of Biological Chemistry, 297 (1). 100834.

Chapman, Paul R., Webster, Rebecca, Giacomin, Paul, Llewellyn, Stacey, Becker, Luke, Pearson, Mark, De Labastida Rivera, Fabian, O’Rourke, Peter, Engwerda, Christian R., Loukas, Alex, and McCarthy, James S. (2021) Vaccination of human participants with attenuated Necator americanus hookworm larvae and human challenge in Australia: a dose-finding study and randomised, placebo-controlled, phase 1 trial. Lancet Infectious Diseases, 21 (12). pp. 1725-1736.

Buitrago, Geraldine, Pickering, Darren, Ruscher, Roland, Cobos Caceres, Claudia, Jones, Linda, Cooper, Martha, Van Waardenberg, Ashley, Ryan, Stephanie, Miles, Kim, Field, Matthew, Dredge, Keith, Daly, Norelle L., Giacomin, Paul R., and Loukas, Alex (2021) A netrin domain-containing protein secreted by the human hookworm Necator americanus protects against CD4 T cell transfer colitis. Translational Research, 232. pp. 88-102.

Logan, Jayden, Pearson, Mark S., Manda, Srikanth S., Choi, Young-Jun, Field, Matthew, Eichenberger, Ramon M., Mulvenna, Jason, Nagaraj, Shivashankar H., Fujiwara, Ricardo T., Gazzinelli-Guimaraes, Pedro, Bueno, Lilian, Mati, Vitor, Bethony, Jeffrey M., Mitreva, Makedonka, Sotillo, Javier, and Loukas, Alex (2020) Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms. PLoS Neglected Tropical Diseases, 14 (5). e0008237.

Wangchuk, Phurpa, Lavers, Owen, Wishart, David, and Loukas, Alex (2020) Excretory/secretory metabolome of the zoonotic roundworm parasite Toxocara canis. Biomolecules, 10 (8). 1157.

Takjoo, Rozita, Wilson, David T., Bansal, Paramjit, Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2020) Folding of truncated granulin peptides. Biomolecules, 10 (8). 1152.

Ryan, Stephanie M., Eichenberger, Ramon M., Ruscher, Roland, Giacomin, Paul R., and Loukas, Alex (2020) Harnessing helminth-driven immunoregulation in the search for novel therapeutic modalities. PLoS Pathogens, 16 (5). e1008508.

Hays, Russell, Pierce, Doris, Giacomin, Paul, Loukas, Alex, Bourke, Peter, and McDermott, Robyn (2020) Helminth coinfection and COVID-19: an alternate hypothesis. PLoS Neglected Tropical Diseases, 14 (8). e0008628.

Hoffmann, Karl F., Hokke, Cornelis H., Loukas, Alex, and Buck, Amy H. (2020) Helminth extracellular vesicles: great balls of wonder. International Journal for Parasitology, 50 (9). pp. 621-622.

Bouchery, Tiffany, Moyat, Mati, Sotillo, Javier, Silverstein, Solomon, Volpe, Beatrice, Coakley, Gillian, Tsourouktsoglou, Theodora-Dorita, Becker, Luke, Shah, Kathleen, Kulagin, Manuel, Guiet, Romain, Camberis, Mali, Schmidt, Alfonso, Seitz, Arne, Giacomin, Paul, Le Gros, Graham, Papayannopoulos, Venizelos, Loukas, Alex, and Harris, Nicola L. (2020) Hookworms evade host immunity by secreting a deoxyribonuclease to degrade neutrophil extracellular traps. Cell Host & Microbe, 27 (2). 277-289.e6.

Mbanefo, Evaristus C., Agbo, Chinwike Terry, Zhao, Yuanlong, Lamanna, Olivia K., Thai, Kim H., Karinshak, Shannon E., Khan, Mohammad Afzal, Fu, Chi-Ling, Odegaard, Justin I., Saltikova, Irina V., Smout, Michael J., Pennington, Luke F., Nicolls, Mark R., Jardetzky, Theodore S., Loukas, Alex, Brindley, Paul J., Falcone, Franco H., and Hsieh, Michael H. (2020) IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis. Infectious Agents and Cancer, 15. 63.

Schmidt, Casey A., Wilson, David T., Cooke, Ira, Potriquet, Jeremy, Tungatt, Katie, Muruganandah, Visai, Boote, Chloe, Kuek, Felicity, Miles, John J., Kupz, Andreas, Ryan, Stephanie, Loukas, Alex, Bansal, Paramjit S., Takjoo, Rozita, Miller, David J., Peigneur, Steve, Tytgat, Jan, and Daly, Norelle (2020) Identification and characterization of a peptide from the stony coral Heliofungia actiniformis. Journal of Natural Products, 83 (11). pp. 3454-3463.

Bartlett, Stacey, Eichenberger, Ramon M., Nevagi, Reshma J., Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Dai, Yang, Loukas, Alex, Toth, Istvan, and Skwarczynski, Mariusz (2020) Lipopeptide-based oral vaccine against hookworm infection. Journal of Infectious Diseases, 221 (6). pp. 934-942.

Arunsan, Patpicha, Chaidee, Apisit, Cochran, Christina J., Mann, Victoria H., Tanno, Toshihiko, Kumkhaek, Chutima, Smout, Michael J., Karinshak, Shannon E., Rodpai, Rutchanee, Sotillo, Javier, Loukas, Alex, Laha, Thewarach, Brindley, Paul J., and Ittiprasert, Wannaporn (2020) Liver fluke granulin promote extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma. Neoplasia, 22 (5). pp. 203-216.

Yeshi, Karma, Creek, Darren J., Anderson, Dovile, Ritmejerytė, Edita, Becker, Luke, Loukas, Alex, and Wangchuk, Phurpa (2020) Metabolomes and lipidomes of the infective stages of the gastrointestinal nematodes, Nippostrongylus brasiliensis and Trichuris muris. Metabolites, 10 (11). 446.

Ng, Susanna S., Rivera, Fabian De Labastida, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C.M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., de Oca, Marcela Montes, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona, Edwards, Chelsea L., Haque, Ashraful, Dougall, William C., Singh, Om Prakash, Baxter, Alan G., Teng, Michele W.L., Loukas, Alex, Daly, Norelle L., Cloonan, Nicole, Degli-esposti, Mariapia, Uzonna, Jude, Heath, William R., Bald, Tobias, Tey, Siok-Keen, Nakamura, Kyohei, Hill, Geoffrey R., Kumar, Rajiv, Sundar, Shyam, Smyth, Mark J, and Engwerda, Christian R. (2020) The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology, 21. pp. 1205-1217.

Thi Phung, Luyen, Chaiyadet, Sujittra, Hongsrichan, Nuttanan, Sotillo, Javier, Dinh Thi Dieu, Hang, Quang Tran, Canh, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2020) Partial protection with a chimeric tetraspanin-leucine aminopeptidase subunit vaccine against Opisthorchis viverrini infection in hamsters. Acta Tropica, 204. 105355.

Kifle, Desalegn Woldeyohannes, Pearson, Mark S., Becker, Luke, Pickering, Darren, Loukas, Alex, and Sotillo, Javier (2020) Proteomic analysis of two populations of Schistosoma mansoni-derived extracellular vesicles: 15k pellet and 120k pellet vesicles. Molecular and Biochemical Parasitology, 236. 111264.

Croese, John, Miller, Gregory C., Marquart, Louise, Llewellyn, Stacey, Gupta, Rohit, Becker, Luke, Clouston, Andrew D., Welch, Christine, Sidorenko, Julia, Wallace, Leanne, Visscher, Peter M., Remedios, Matthew L., McCarthy, James S., O'Rourke, Peter, Radford-Smith, Graham, Loukas, Alex, Norrie, Mark, Masson, John W., Gearry, Richard B., Rahman, Tony, and Giacomin, Paul (2020) Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in Celiac disease. Clinical and Translational Gastroenterology, 11. e00274.

Suwannatrai, Kulwadee, Suwannatrai, Apiporn Thinkhamrop, Loukas, Alex, and Sotillo, Javier (2020) Recent advances on the immunobiology of Bithynia spp. hosts of Opisthorchis viverrini. Developmental and Comparative Immunology, 102. 103460.

Yeshi, Karma, Ruscher, Roland, Hunter, Luke, Daly, Norelle, Loukas, Alex, and Wangchuk, Phurpa (2020) Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products. Journal of Clinical Medicine, 9 (5). 1273.

Mekonnen, Gebeyaw G., Tedla, Bemnet A., Pickering, Darren, Becker, Luke, Wang, Lei, Zhan, Bin, Bottazzi, Maria Elena, Loukas, Alex, Sotillo, Javier, and Pearson, Mark S. (2020) Schistosoma haematobium extracellular vesicle proteins confer protection in a heterologous model of schistosomiasis. Vaccines, 8 (3). 416.

Kifle, Desalegn Woldeyohannes, Chaiyadet, Sujittra, Waardenberg, Ashley J., Wise, Ingrid, Cooper, Martha, Becker, Luke, Doolan, Denise L., Laha, Thewarach, Sotillo, Javier, Pearson, Mark S., and Loukas, Alex (2020) Uptake of Schistosoma mansoni extracellular vesicles by human endothelial and monocytic cell lines and impact on vascular endothelial cell gene expression. International Journal for Parasitology, 50 (9). pp. 685-696.

Tedla, Bemnet, Pickering, Darren, Becker, Luke, Loukas, Alex, and Pearson, Mark S. (2020) Vaccination with Schistosoma mansoni cholinesterases reduces the parasite burden and egg viability in a mouse model of Schistosomiasis. Vaccines, 8 (2). 162.

Tedla, Bemnet A., Sotillo, Javier, Pickering, Darren, Eichenberger, Ramon M., Ryan, Stephanie, Becker, Luke, Loukas, Alex, and Pearson, Mark S. (2019) Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signaling and drug detoxification and are essential for parasite survival. PLoS Pathogens, 15 (12). e1008213.

Wangchuk, Phurpa, Constantinoiu, Constantin, Eichenberger, Ramon M., Field, Matt, and Loukas, Alex (2019) Characterization of tapeworm metabolites and their reported biological activities. Molecules, 24 (8). 1480.

Langdon, Kane, Phie, James, Thapa, Chetan B., Biros, Erik, Loukas, Alex, and Haleagrahara, Nagaraja (2019) Helminth-based therapies for rheumatoid arthritis: a systematic review and meta-analysis. International Immunopharmacology, 66. pp. 366-372.

Wangchuk, Phurpa, Shepherd, Catherine, Constantinoiu, Constantin, Ryan, Rachael Y.M., Kouremenos, Konstantinos A., Becker, Luke, Jones, Linda, Buitrago, Geraldine, Giacomin, Paul, Wilson, David, Daly, Norelle, Mcconville, Malcolm J., Miles, John J., and Loukas, Alex (2019) Hookworm-derived metabolites suppress pathology in a mouse model of colitis and inhibit secretion of key inflammatory cytokines in primary human leukocytes. Infection and Immunity, 87 (4). e00851-18.

Sotillo, Javier, Pearson, Mark S., Becker, Luke, Mekonnen, Gebeyaw G., Amoah, Abena S., Van Dam, Govert, Corstjens, Paul L.A.M., Murray, Janice, Mduluza, Takafira, Mutapi, Francisca, and Loukas, Alex (2019) In-depth proteomic characterization of Schistosoma haematobium: towards the development of new tools for elimination. PLoS Neglected Tropical Diseases, 13 (5). e0007362.

Chenery, Alistair L., Alhallaf, Rafid, Agha, Zainab, Ajendra, Jesuthas, Parkinson, James E., Cooper, Martha M., Chan, Brian H. K., Eichenberger, Ramon M., Dent, Lindsay A., Robertson, Avril A. B., Kupz, Andreas, Brough, David, Loukas, Alex, Sutherland, Tara E., Allen, Judith E., and Giacomin, Paul R. (2019) Inflammasome-independent role for NLRP3 in controlling innate antihelminth immunity and tissue repair in the lung. Journal of Immunology, 203 (10). 1900640. pp. 2724-2734.

Wangchuk, Phurpa, Kouremenos, Konstantinos, Eichenberger, Ramon M., Pearson, Mark, Susianto, Atik, Wishart, David S., McConville, Malcolm J., and Loukas, Alex (2019) Metabolomic profling of the excretory–secretory products of hookworm and whipworm. Metabolomics, 15. 101.

Hoogerwerf, Marie-Astrid, Coffeng, Luc E., Brienen, Eric A. T., Janse, Jacqueline J., Langenberg, Marijke C. C., Kruize, Yvonne C. M., Gootjes, Chelsea, Manurung, Mikhael D., Dekker, Mark, Becker, Luke, Erkens, Marianne A.A., van der Beek, Martha T., Ganesh, Munisha S., Feijt, Carola, Winkel, Beatrice M. F., Westra, Inge M., Meij, Pauline, Loukas, Alex, Visser, Leo G., de Vlas, Sake J., Yazdanbakhsh, Maria, van Lieshout, Lisette, and Roestenberg, Meta (2019) New insights into the kinetics and variability of egg excretion in controlled human hookworm infections. Journal of Infectious Diseases, 220 (6). pp. 1044-1048.

Arunsan, Patpicha, Ittiprasert, Wannaporn, Smout, Michael J., Cochran, Christina J., Mann, Victoria H., Chaiyadet, Sujittra, Karinshak, Shannon E., Sripa, Banchob, Young, Neil David, Sotillo, Javier, Loukas, Alex, Brindley, Paul J., and Laha, Thewarach (2019) Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity. eLife, 8. e41463.

Phung, Luyen Thi, Chaiyadet, Sujittra, Hongsrichan, Nuttanan, Sotillo, Javier, Dieu, Hang Dinh Thi, Tran, Canh Quang, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2019) Recombinant Opisthorchis viverrini tetraspanin expressed in Pichia pastoris as a potential vaccine candidate for opisthorchiasis. Parasitology Research, 118. pp. 3419-3427.

Pierce, Doris, Merone, Lea, Lewis, Chris, Rahman, Tony, Croese, John, Loukas, Alex, McDonald, Malcolm, Giacomin, Paul, and McDermott, Robyn (2019) Safety and tolerability of experimental hookworm infection in humans with metabolic disease: study protocol for a phase 1b randomised controlled clinical trial. BMC Endocrine Disorders, 19. 136.

Sotillo, Javier, Pearson, Mark S., and Loukas, Alex (2019) Trematode genomics and proteomics. In: Toledo, Rafael, and Fried, Bernard, (eds.) Digenetic Trematodes. Advances in Experimental Medicine and Biology, 1154 . Springer, Cham, Switzerland, pp. 411-436.

Chaiyadet, Sujittra, Sotillo, Javier, Krueajampa, Watchara, Thongsen, Sophita, Brindley, Paul J., Sripa, Banchob, Loukas, Alex, and Laha, Thewarach (2019) Vaccination of hamsters with Opisthorchis viverrini extracellular vesicles and vesicle-derived recombinant tetraspanins induces antibodies that block vesicle uptake by cholangiocytes and reduce parasite burden after challenge infection. PLoS Neglected Tropical Diseases, 13 (5). e0007450.

Eichenberger, Ramon M., Hasanuzzaman, Talukder, Field, Matt A., Wangchuk, Phurpa, Giacomin, Paul, Loukas, Alex, and Sotillo, Javier (2018) Characterization of Trichuris muris secreted proteins and extracellular vesicles provides new insights into host–parasite communication. Journal of Extracellular Vesicles, 7 (1). 1428004.

Wangchuk, Phurpa, Apte, Simon H., Smout, Michael J., Groves, Penny L., Loukas, Alex, and Doolan, Denise L. (2018) Defined small molecules produced by Himalayan medicinal plants display immunomodulatory properties. International Journal of Molecular Sciences, 19 (11). 3490.

Yan, Hong-Bin, Smout, Michael J., Ju, Chuan, Folley, Anne E., Skinner, Danielle E., Mann, Victoria H., Loukas, Alex, Hu, Wei, Brindley, Paul J., and Rinaldi, Gabriel (2018) Developmental sensitivity in Schistosoma mansoni to puromycin to establish drug selection of transgenic schistosomes. Antimicrobial Agents and Chemotherapy, 62 (8). e02568-17.

Cobos, Claudia, Bansal, Paramjit S., Jones, Linda, Wangchuk, Phurpa, Wilson, David, Loukas, Alex, and Daly, Norelle L. (2018) Engineering of an anti-inflammatory peptide based on the disulfide-rich linaclotide scaffold. Biomedicines, 6 (4). 97.

Mekonnen, Gebeyaw Getnet, Pearson, Mark, Loukas, Alex, and Sotillo, Javier (2018) Extracellular vesicles from parasitic helminths and their potential utility as vaccines. Expert Review of Vaccines, 17 (3). pp. 197-205.

Wendt, George R., Collins, Julie N.R., Pei, Jimin, Pearson, Mark S., Bennett, Hayley M., Loukas, Alex, Berriman, Matthew, Grishin, Nick V., and Collins III, James J. (2018) Flatworm-specific transcriptional regulators promote the specification of tegumental progenitors in Schistosoma mansoni. eLife, 7. e33221.

Dastpeyman, Mohadeseh, Smout, Michael J., Wilson, David, Loukas, Alex, and Daly, Norelle L. (2018) Folding of granulin domains. Peptide Science, 110 (3). e24062.

Haugen, Brandon, Karinshak, Shannon E., Mann, Victoria H., Popratiloff, Anastas, Loukas, Alex, Brindley, Paul J., and Smout, Michael J. (2018) Granulin secreted by the food-borne liver fluke Opisthorchis viverrini promotes angiogenesis in human endothelial cells. Frontiers in Medicine, 5. 30.

Logan, Jayden, Navarro, Severine, Loukas, Alex, and Giacomin, Paul (2018) Helminth-induced regulatory T cells and suppression of allergic responses. Current Opinion in Immunology, 54. pp. 1-6.

Eichenberger, Ramon M., Ryan, Stephanie, Jones, Linda, Buitrago, Geraldine, Polster, Ramona, Montes de Oca, Marcela, Zuvelek, Jennifer, Giacomin, Paul R., Dent, Lindsay A., Engwerda, Christian R., Field, Matthew A., Sotillo, Javier, and Loukas, Alex (2018) Hookworm secreted extracellular vesicles interact with host cells and prevent inducible colitis in mice. Frontiers in Immunology, 9.

Eichenberger, Ramon M., Sotillo, Javier, and Loukas, Alex (2018) Immunobiology of parasitic worm extracellular vesicles. Immunology and Cell Biology, 96 (7). pp. 704-713.

Alhallaf, Rafid, Agha, Zainab, Miller, Catherine M., Robertson, Avril A.B., Sotillo-Gallego, Javier, Croese, John, Cooper, Matthew A., Masters, Seth L., Kupz, Andreas, Smith, Nicholas C., Loukas, Alex, and Giacomin, Paul R. (2018) The NLRP3 inflammasome suppresses protective immunity to gastrointestinal helminth infection. Cell Reports, 23 (4). pp. 1085-1098.

Shepherd, Catherine, Wangchuk, Phurpa, and Loukas, Alex (2018) Of dogs and hookworms: man's best friend and his parasites as a model for translational biomedical research. Parasites & Vectors, 11. 59.

Suttiprapa, Sutas, Sotillo, Javier, Smout, Michael, Suyapoh, Watcharapol, Chaiyadet, Sujittra, Tripathi, Timir, Laha, Thewarach, and Loukas, Alex (2018) Opisthorchis viverrini proteome and host-parasite interactions. In: UNSPECIFIED, (ed.) Advances in Parasitology. Advances in Parasitology, 102 . Elsevier, London, UK, pp. 45-72.

Sundaraneedi, Madhu, Eichenberger, Ramon M., Al-Hallaf, Rafid, Yang, Dai, Sotillo, Javier, Rajan, Siji, Wangchuk, Phurpa, Giacomin, Paul R., Keene, F. Richard, Loukas, Alex, Collins, J. Grant, and Pearson, Mark S. (2018) Polypyridylruthenium(II) complexes exert in vitro and in vivo nematocidal activity and show significant inhibition of parasite acetylcholinesterases. International Journal for Parasitology: Drugs and Drugs Resistance, 8 (1). pp. 1-7.

Weeks, Janis C., Roberts, William M., Leasure, Caitlyn, Suzuki, Brian M., Robinson, Kristin J., Currey, Heather, Wangchuk, Phurpa, Eichenberger, Ramon M., Saxton, Aleen D., Bird, Thomas D., Kraemer, Brian C., Loukas, Alex, Hawdon, John M., Caffrey, Conor R., and Liachko, Nicole F. (2018) Sertraline, paroxetine, and chlorpromazine are rapidly acting anthelmintic drugs capable of clinical repurposing. Scientific Reports, 8.

Dastpeyman, Mohadeseh, Bansal, Paramjit S., Wilson, David, Sotillo, Javier, Brindley, Paul J., Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2018) Structural variants of a liver fluke derived granulin peptide potently stimulate wound healing. Journal of Medicinal Chemistry, 61 (19). pp. 8746-8753.

Phumrattanaprapin, Wuttipong, Chaiyadet, Sujittra, Loukas, Alex, Brindley, Paul J., Sotillo, Javier, and Laha, Thewarach (2018) Surface display on Bacillus subtilis spores and vaccine potential of a Tetraspanin fromm caniogenic liver fluke Opisthorchis viverrini. Southeast Asian Journal of Tropical Medicine and Public Health, 49 (6). pp. 933-948.

Wangchuk, Phurpa, and Loukas, Alex (2018) Techniques and technologies for the biodiscovery of novel small molecule drug lead compounds from natural products. In: Mandal, Subhash C., Mandal, Vivekananda, and Konishi, Tetsuya, (eds.) Natural Products and Drug Discovery: An Integrated Approach. Elsevier, Amsterdam, Netherlands, pp. 435-465.

Shepherd, Catherine, Giacomin, Paul, Navarro, Severine, Miller, Catherine M., Loukas, Alex, and Wangchuk, Phurpa (2018) A medicinal plant compound, capnoidine, prevents the onset of inflammation in a mouse model of colitis. Journal of Ethnopharmacology, 211. pp. 17-28.

Bouchery, Tiffany, Filbey, Kara, Shepherd, Amy, Chandler, Jodie, Patel, Deepa, Schmidt, Alfonso, Camberis, Mali, Peignier, Adeline, Smith, Adam A.T., Johnston, Karen, Painter, Gavin, Pearson, Mark, Giacomin, Paul, Loukas, Alex, Bottazzi, Maria-Elena, Hotez, Peter, and LeGros, Graham (2018) A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathogens, 14 (3).

Sundaraneedi, Madhu K., Tedla, Bemnet A., Eichenberger, Ramon M., Becker, Luke, Pickering, Darren, Smout, Michael J., Rajan, Siji, Wangchuk, Phurpa, Keene, F. Richard, Loukas, Alex, Collins, J. Grant, and Pearson, Mark S. (2017) Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases. PLoS Neglected Tropical Diseases, 11 (12). e0006134.

Deenonpoe, Raksawan, Mairiang, Eimorn, Mairiang, Pisaln, Pairojkul, Chawalit, Chamgramol, Yaovalux, Rinaldi, Gabriel, Loukas, Alex, Brindley, Paul J., and Sripa, Banchob (2017) Elevated prevalence of Helicobacter species and virulence factors in opisthorchiasis and associated hepatobiliary disease. Scientific Reports, 7. 42744.

Sotillo, Javier, Ferreira, Ivana, Potriquet, Jeremy, Laha, Thewarach, Navarro, Severine, Loukas, Alex, and Mulvenna, Jason (2017) Changes in protein expression after treatment with Ancylostoma caninum excretory/secretory products in a mouse model of colitis. Scientific Reports, 7. 41883.

Jin, Ai-Hua, Dekan, Zoltan, Smout, Michale J., Wilson, David, Dutertre, Sebastien, Vetter, Irina, Lewis, Richard J., Loukas, Alex, Daly, Norelle L., and Alewood, Paul F. (2017) Conotoxin Phi-MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie International Edition, 56 (47). pp. 14973-14976.

Bansal, Paramjit S., Smout, Michael J., Wilson, David, Cobos Caceres, Claudia, Dastpeyman, Mohadeseh, Sotillo, Javier, Seifert, Julia, Brindley, Paul J., Loukas, Alex, and Daly, Norelle L. (2017) Development of a potent wound healing agent based on the liver fluke granulin structural fold. Journal of Medicinal Chemistry, 60 (10). pp. 4258-4266.

Sotillo, Javier, Toledo, Rafael, Mulvenna, Jason, and Loukas, Alex (2017) Exploiting helminth-host interactomes through Big Data. Trends in Parasitology, 33 (11). pp. 875-888.

Kifle, Desalegn Woldeyohannes, Sotillo, Javier, Pearson, Mark S., and Loukas, Alex (2017) Extracellular vesicles as a target for the development of anti-helminth vaccines. Emerging Topics in Life Sciences, 1 (6). pp. 659-665.

Smallwood, Taylor B., Giacomin, Paul R., Loukas, Alex, Mulvenna, Jason P., Clark, Richard J., and Miles, John J. (2017) Helminth immunomodulation in autoimmune disease. Frontiers in Immunology, 8. 453.

Brindley, Paul J., and Loukas, Alex (2017) Helminth infection-induced malignancy. PLoS Pathogens, 13 (7). e1006393.

Chaiyadet, Sujittra, Smout, Michael, Laha, Thewarach, Sripa, Banchob, Loukas, Alex, and Sotillo, Javier (2017) Proteomic characterization of the internalization of Opisthorchis viverrini excretory/secretory products in human cells. Parasitology International, 66 (4). pp. 494-502.

Sotillo, Javier, Doolan, Denise, and Loukas, Alex (2017) Recent advances in proteomic applications for schistosomiasis research: potential clinical impact. Expert Review of Proteomics, 14 (2). pp. 171-183.

Morante, Taylor, Shepherd, Catherine, Constantinoiu, Constantin, Loukas, Alex, and Sotillo, Javier (2017) Revisiting the Ancylostoma caninum secretome provides new information on hookworm-host interactions. Proteomics, 17 (23-24). 1700176.

Lima, Luciane Mota, Cardoso, Luciana Santos, Santos, Silvane Braga, Oliveira, Ricardo Riccio, Oliveira, Sergio Costa, Goes, Alfredo Miranda, Loukas, Alex, and Araujo, Maria (2017) Schistosoma antigens downregulate CXCL9 production by PBMC of HTLV-1-infected individuals. Acta Tropica, 167. pp. 157-162.

Ferreira, Ivana B., Pickering, Darren A., Troy, Sally, Croese, John, Loukas, Alex, and Navarro, Severine (2017) Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis. Clinical & Translational Immunology, 6. e157.

Chaiyadet, Sujittra, Krueajampa, Watchara, Hipkaeo, Wiphawi, Plosan, Yada, Piratae, Supawadee, Sotillo, Javier, Smout, Michael, Sripa, Banchob, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2017) Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes. Scientific Reports, 7. 14342.

Sundaraneedi, Madhu K., Ammit, Alaina, Tedla, Bemnet A., Pearson, Mark S., Loukas, Alex, Keene, F. Richard, and Collins, J. Grant (2017) Tetranuclear polypyridylruthenium(II) complexes as inhibitors and down-regulators of phosphatase enzymes. ChemistrySelect, 2 (33). pp. 10668-10672.

Wilson, David, Boyle, Glen M., McIntyre, Lachlan, Nolan, Matthew J., Parsons, Peter G., Smith, Jennifer J., Tribolet, Leon, Loukas, Alex, Liddell, Michael J., Rash, Lachlan D., and Daly, Norelle L. (2017) The aromatic head group of spider toxin polyamines influences toxicity to cancer cells. Toxins, 9 (11). 9110346. pp. 1-13.

Cobos Caceres, Claudia, Bansal, Paramjit S., Navarro, Severine, Wilson, David, Don, Laurianne, Giacomin, Paul, Loukas, Alex, and Daly, Norelle L. (2017) An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease. Journal of Biological Chemistry, 292 (24). pp. 10288-10294.

Wangchuk, Phurpa, Pearson, Mark S., Giacomin, Paul R., Becker, Luke, Sotillo, Javier, Pickering, Darren, Smout, Michael J., and Loukas, Alex (2016) Compounds derived from the Bhutanese daisy, Ajania nubigena, demonstrate dual anthelmintic activity against Schistosoma mansoni and Trichuris muris. PLOS Neglected Tropical Diseases, 10 (8). e0004908. pp. 1-18.

Susilawati, T.N., Jex, A.R., Cantacessi, C., Pearson, M., Navarro, S., Susianto, A., Loukas, A.C., and McBride, W.J.H. (2016) Deep sequencing approach for investigating infectious agents causing fever. European Journal of Clinical Microbiology and Infectious Diseases, 35 (7). pp. 1137-1149.

Papatpremsiri, A., Junpue, P., Loukas, A., Brindley, P.J., Bethony, J.M., Sripa, B., and Laha, T. (2016) Immunization and challenge shown by hamsters infected with Opisthorchis viverrini following exposure to gamma-irradiated metacercariae of this carcinogenic liver fluke. Journal of Helminthology, 90 (1). pp. 39-47.

Driguez, Patrick, Li, Yuesheng, Gaze, Soraya, Pearson, Mark S., Nakajima, Rie, Trieu, Angela, Doolan, Denise L., Felgner, Philip L., Hou, Xunya, Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey, Loukas, Alex, and McManus, Donald (2016) Antibody signatures reflect different disease pathologies in patients with schistosomiasis due to Schistosoma japonicum. Journal of Infectious Diseases, 213 (1). pp. 122-130.

Giacomin, Paul, Zakrzewski, Martha, Jenkins, Timothy P., Su, Xiaopei, Al-Hallaf, Rafid, Croese, John, De Vries, Stefan, Grant, Andrew, Mitreva, Makedonka, Krause, Lutz, Loukas, Alex, and Cantacessi, Cinzia (2016) Changes in duodenal tissue-associated microbiota following hookworm infection and consecutive gluten challenges in humans with coeliac disease. Scientific Reports, 6. 36797. pp. 1-10.

Loukas, Alex, and Giacomin, Paul (2016) Developments in the design of anti-helminth vaccines. In: Gause, William C., and Artis, David, (eds.) The Th2 Type Immune Response in Health and Disease: from host defense and allergy to metabolic homeostasis and beyond. Springer, New York, NY, USA, pp. 97-114.

Suwannatrai, Kulwadee, Suwannatrai, Apiporn, Tabsripair, Pairat, Welbat, Jariya Umka, Tangkawattana, Sirikachorn, Cantacessi, Cinzia, Mulvenna, Jason, Tesana, Smarn, Loukas, Alex, and Sotillo, Javier (2016) Differential protein expression in the hemolymph of Bithynia siamensis goniomphalos infected with Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 10 (11). e0005104.

Sotillo, Javier, Pearson, Mark, Potriquet, Jeremy, Becker, Luke, Pickering, Darren, Mulvenna, Jason, and Loukas, Alex (2016) Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates. International Journal for Parasitology, 46 (1). pp. 1-5.

Giacomin, Paul, Agha, Zainab, and Loukas, Alex (2016) Helminths and intestinal flora team up to improve gut health. Trends in Parasitology, 32 (9). pp. 664-666.

Navarro, Severine, Pickering, Darren A., Ferreira, Ivana B., Jones, Linda, Ryan, Stephanie, Troy, Sally, Leech, Andrew , Hotez, Peter J., Zhan, Bin, Laha, Thewarach, Prentice, Roger, Sparwasser, Tim, Croese, John, Engwerda, Christian R., Upham, John W., Julia, Valerie, Giacomin, Paul R., and Loukas, Alex (2016) Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine, 8 (362). 362ra143.

Wangchuk, Phurpa, Giacomin, Paul R., Pearson, Mark S., Smout, Michael J., and Loukas, Alex (2016) Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms. Scientific Reports, 6. 32101. pp. 1-10.

Tebeje, Biniam Mathewos, Harvie, Marina, You, Hong, Loukas, Alex, and McManus, Donald P. (2016) Schistosomiasis vaccines: where do we stand? Parasites & Vectors, 9. 528. pp. 1-15.

Driguez, Patrick, McWilliam, Hamish E.G., Gaze, Soraya, Piedrafita, David, Pearson, Mark S., Nakajima, Rie, Duke, Mary, Trieu, Angela, Doolan, Denise L., Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey N., Felgner, Philip L., Loukas, Alex, Meeusen, Els, and McManus, Donald P. (2016) Specific humoral response of hosts with variable schistosomiasis susceptibility. Immunology and Cell Biology, 94. pp. 52-65.

de Assis, Rafael Ramiro, Ludolf, Fernanda, Nakajima, Rie, Jasinskas, Al, Oliveira, Guilherme C., Felgner, Philip, Gaze Jangola, Soraya T., Loukas, Alex, LoVerde, Philip T., Bethony, Jeffrey M., Correa-Oliveira, Rodrigo, and Calzavara-Silva, Carlos E. (2016) A next-generation proteome array for Schistosoma mansoni. International Journal for Parasitology, 46 (7). pp. 411-415.

Rinaldi, Gabriel, Loukas, Alex, Brindley, Paul J., Irelan, Jeff T., and Smout, Michael J. (2015) Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM). International Journal for Parasitology: Drugs and Drugs Resistance, 5 (3). pp. 141-148.

Zaiss, Mario M., Rapin, Alexis, Lebon, Luc, Dubey, Lalit Kumar, Mosconi, Ilaria, Sarter, Kerstin, Piersigilli, Alessandra, Menin, Laure, Walker, Alan W., Rougemont, Jacques, Paerewijck, Oonagh, Geldhof, Peter, McCoy, Kathleen D., Macpherson, Andrew J., Croese, John, Giacomin, Paul R., Loukas, Alex, Junt, Tobias, Marsland, Benjamin J., and Harris, Nicola L. (2015) The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation. Immunity, 43 (5). pp. 998-1010.

Worasith, Chanika, Kamamia, Christine, Yakovleva, Anna, Duenngai, Kunyarat, Wangboon, Chompunoot, Sithithaworn, Jiraporn, Watwiengkam, Nattaya, Namwat, Nisana, Techasen, Anchalee, Loilome, Watcharin, Yongvanit, Puangrat, Loukas, Alex, Sithithaworn, Paiboon, and Bethony, Jeffrey M. (2015) Advances in the diagnosis of human Opisthorchiasis: development of Opisthorchis viverrini antigen detection in urine. PLoS Neglected Tropical Diseases, 9 (10). e0004157. pp. 1-18.

Smout, Michael J., Sotillo, Javier, Laha, Thewarach, Papatpremsiri, Atiroch, Rinaldi, Gabriel, Pimenta, Rafael N., Chan, Lai Yue, Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Giacomin, Paul R., Moran, Corey S., Golledge, Jonathan, Daly, Norelle, Sripa, Banchob, Mulvenna, Jason P., Brindley, Paul J., and Loukas, Alex (2015) Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia. PLoS Pathogens, 11 (10). e100520. pp. 1-20.

Chaiyadet, Sujittra, Smout, Michael, Johnson, Michael, Whitchurch, Cynthia, Turnbull, Lynne, Kaewkes, Sasithorn, Sotillo, Javier, Loukas, Alex, and Sripa, Banchob (2015) Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production. International Journal for Parasitology, 45 (12). pp. 773-781.

Giacomin, Paul, Zakrzewski, Martha, Croese, John, Su, Xiaopei, Sotillo, Javier, McCann, Leisa, Navarro, Severine, Mitreva, Makedonka, Krause, Lutz, Loukas, Alex, and Cantacessi, Cinzia (2015) Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects. Scientific Reports, 5. 13797. pp. 1-8.

Wangchuk, Phurpa, Navarro, Severine, Shepherd, Catherine, Keller, Paul A., Pyne, Stephen G., and Loukas, Alex (2015) Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis. Scientific Reports, 5. 12845. pp. 1-10.

Giacomin, Paul, Croese, John, Krause, Lutz, Loukas, Alex, and Cantacessi, Cinzia (2015) Suppression of inflammation by helminths: a role for the gut microbiota. Philosophical Transactions of the Royal Society B: Biological Sciences, 370 (1675). 20140296. pp. 1-6.

Sotillo, Javier, Pearson, Mark, Becker, Luke, Mulvenna, Jason, and Loukas, Alex (2015) A quantitative proteomic analysis of the tegumental proteins from Schistosoma mansoni schistosomula reveals novel potential therapeutic targets. International Journal for Parasitology, 45 (8). pp. 505-516.

Shepherd, C., Navarro, S., Wangchuk, P., Wilson, D., Daly, N.L., and Loukas, A. (2015) Identifying the immunomodulatory components of helminths. Parasite Immunology, 37 (6). pp. 293-303.

Pearson, Mark S., Becker, Luke, Driguez, Patrick, Young, Neil D., Gaze Jangola, Soraya, Mendes, Tiago, Li, Xiao-Hong, Doolan, Denise L., Midzi, Nicholas, Mduluza, Takafira, McManus, Donald P., Wilson, R. Alan, Bethony, Jeffrey M., Nausch, Norman, Mutapi, Francisca, Felgner, Philip L., and Loukas, Alex (2015) Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Frontiers in Immunology, 6. 213. pp. 1-13.

Pearson, Mark S., Jariwala, Amar R., Abbenante, Giovanni, Plieskatt, Jordan, Wilson, David, Bottazzi, Maria Elena, Hotez, Peter J., Keegan, Brian, Bethony, Jeffrey M., and Loukas, Alex (2015) New tools for NTD vaccines: a case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Human Vaccines & Immunotherapeutics, 11 (5). pp. 1251-1257.

Prasopdee, Sattrachai, Tesana, Smarn, Cantacessi, Cinzia, Laha, Thewarach, Mulvenna, Jason, Grams, Rudi, Loukas, Alex, and Sotillo, Javier (2015) Data set from the proteomic analysis of Bithynia siamensis goniomphalos snails upon infection with the carcinogenic liver fluke Opisthorchis viverrini. Data in Brief, 2. pp. 16-20.

Hays, Russell, Esterman, Adrian, Giacomin, Paul, Loukas, Alex, and McDermott, Robyn (2015) Does Strongyloides stercoralis infection protect against type 2 diabetes in humans? Evidence from Australian Aboriginal adults. Diabetes Research and Clinical Practice, 107 (3). pp. 355-361.

Tribolet, Leon, Cantacessi, Cinzia, Pickering, Darren, Navarro, Severine, Doolan, Denise, Trieu, Angela, Fei, Huang, Chao, Yang, Hofmann, Andreas, Gasser, Robin, Giacomin, Paul, and Loukas, Alex (2015) Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling. Journal of Infectious Diseases, 211 (3). pp. 416-425.

Croese, John, Giacomin, Paul, Navarro, Severine, Clouston, Andrew, McCann, Leisa, Dougall, Annette, Ferreira, Ivana, Susianto, Atik, O'Rourke, Peter, Howlett, Mariko, McCarthy, James, Engwerda, Christian, Jones, Dianne, and Loukas, Alex (2015) Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease. Journal of Allergy and Clinical Immunology, 135 (2). pp. 508-516.

Stoll, Richard, Urban-Klein, Beata, Giacomin, Paul, Loukas, Alex, and Jablonski-Momeni, Anahita (2015) In vivo assessment of caries excavation with a fluorescence camera compared to direct bacteriological sampling and quantitative analysis using flow cytometry. Lasers in Medical Science, 30 (2). pp. 843-849.

Prasopdee, Sattrachai, Kulsantiwong, Jutharat, Piratae, Supawadee, Khampoosa, Panita, Thammasiri, Chalida, Suwannatrai, Apiporn, Laha, Thewarach, Grams, Rudi, Loukas, Alex, and Tesana, Smarn (2015) Temperature dependence of Opisthorchis viverrini infection in first intermediate host snail, Bithynia siamensis goniomphalos. Acta Tropica, 141 (A). pp. 112-117.

Chaiyadet, Sujittra, Sotillo, Javier, Smout, Michael, Cantacessi, Cinzia, Jones, Malcolm K., Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Potriquet, Jeremy, Laohaviroj, Marut, Mulvenna, Jason, Brindley, Paul J., Bethony, Jeffrey M., Laha, Thewarach, Sripa, Banchob, and Loukas, Alex (2015) Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype. Journal of Infectious Diseases, 212 (10). pp. 1636-1645.

Fuaad, Abdullah A.H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzho, Loukas, Alex C., Skwarczynski, Mariusz, and Toth, Istvan (2015) Lipopeptide nanoparticles: development of vaccines against hookworm parasite. ChemMedChem, 10 (10). pp. 1647-1654.

Driguez, Patrick, Doolan, Denise L., Molina, Douglas M., Loukas, Alex, Trieu, Angela, Felgner, Phil L., and McManus, Donald P. (2015) Protein microarrays for parasite antigen discovery. In: Peacock, Christopher, (ed.) Parasite Genomics Protocols. Methods in Molecular Biology (1201). Springer, New York, NY, USA, pp. 221-233.

Prasopdee, Sattrachai, Tesana, Smarn, Cantacessi, Cinzia, Laha, Thewarach, Mulvenna, Jason, Grams, Rudi, Loukas, Alex, and Sotillo, Javier (2015) Proteomic profile of Bithynia siamensis goniomphalos snails upon infection with the carcinogenic liver fluke Opisthorchis viverrini. Journal of Proteomics, 113. pp. 281-291.

Papatpremsiri, Atiroch, Smout, Michael J., Loukas, Alex, Brindley, Paul J., Sripa, Banchob, and Laha, Thewarach (2015) Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells. Experimental Parasitology, 148. pp. 17-23.

Deenonpoe, Raksawan, Chomvarin, Chariya, Pairojkul, Chawalit, Chamgramol, Yaowalux, Loukas, Alex, Brindley, Paul J., and Sripa, Banchob (2015) The carcinogenic liver fluke Opisthorchis viverrini is a reservoir for species of Helicobacter. Asian Pacific Journal of Cancer Prevention, 16 (5). pp. 1751-1758.

Ahmad Fuaad, Abdullah A.H., Roubille, Romain, Pearson, Mark S., Pickering, Darren A., Loukas, Alex C., Skwarczynski, Mariusz, and Toth, Istvan (2015) The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni. Bioorganic & Medicinal Chemistry, 23. pp. 1307-1312.

Sotillo, Javier, Sanchez-Flores, Alejandro, Cantacessi, Cinzia, Harcus, Yvonne, Pickering, Darren, Bouchery, Tiffany, Camberis, Mali, Tang, Shiau-Choot, Giacomin, Paul, Mulvenna, Jason, Mitreva, Makedonka, Berriman, Matthew, LeGros, Graham, Maizels, Rick M., and Loukas, Alex (2014) Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis. Molecular and Cellular Proteomics, 13 (10). pp. 2736-2751.

Zeraik, Ana E., Galkin, Vitold E., Rinaldi, Gabriel, Garratt, Richard C., Smout, Michael J., Loukas, Alex, Mann, Victoria H., Araujo, Ana P.U., DeMarco, Ricardo, and Brindley, Paul J. (2014) Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins. International Journal for Parasitology, 44 (8). pp. 523-531.

Pinheiro, C.S., Ribeiro, A.P.D., Cardoso, F.C., Martins, V.P., Figueiredo, B.C.P., Assis, N.R.G., Morais, S.B., Caliari, M.V., Loukas, A., and Oliveira, S.C. (2014) A multivalent chimeric vaccine composed of Schistosoma mansoni SmTSP-2 and Sm29 was able to induce protection against infection in mice. Parasite Immunology, 36 (7). pp. 303-312.

Mason, Lyndel, Tribolet, Leon, Simon, Anne, von Gnielinski, Natascha, Nienaber, Lisa, Taylor, Paul, Willis, Charlene, Jones, Malcolm K., Sternberg, Paul W., Gasser, Robin B., Loukas, Alex, and Hofmann, Andreas (2014) Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2. International Journal of Biochemistry and Cell Biology , 50. pp. 146-155.

Gaze, Soraya, Driguez, Patrick, Pearson, Mark S., Mendes, Tiago, Doolan, Denise L., Trieu, Angela, McManus, Donald P., Gobert, Geoffrey N., Periago, Maria Victoria, Correa Oliveira, Rodrigo, Cardoso, Fernanda C., Oliveira, Guilherme, Nakajima, Rie, Jasinskas, Al, Hung, Chris, Liang, Li, Pablo, Jozelyn, Bethony, Jeffrey M., Felgner, Philip L., and Loukas, Alex (2014) An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathogens, 10 (3). e1004033. pp. 1-16.

Chaousis, Stephanie, Smout, Michael, Wilson, David, Loukas, Alex, Mulvenna, Jason, and Seymour, Jamie (2014) Rapid short term and gradual permanent cardiotoxic effects of vertebrate toxins from Chironex fleckeri (Australian box jellyfish) venom. Toxicon, 80. pp. 17-26.

Tang, Yat T., Gao, Xin, Rosa, Bruce A., Abubucker, Sahar, Hallsworth-Pepin, Kymberlie, Martin, John, Tyagi, Rahul, Heizer, Esley, Zhang, Xu, Bhonagiri-Palsikar, Veena, Minx, Patrick, Warren, Wesley C., Wang, Qi, Zhan, Bin, Hotez, Peter J., Sternberg, Paul W., Dougall, Annette, Gaze, Soraya Torres, Mulvenna, Jason, Sotillo, Javier, Ranganathan, Shoba, Rabelo, Elida M., Wilson, Richard K., Felgner, Philip L., Bethony, Jeffrey, Hawdon, John M., Gasser, Robin B., Loukas, Alex, and Mitreva, Makedonka (2014) Genome of the human hookworm Necator americanus. Nature Genetics, 46 (3). pp. 261-271.

Prasopdee, Sattrachai, Sotillo, Javier, Tesana, Smarn, Laha, Thewarach, Kulsantiwong, Jutharat, Nolan, Matthew J., Loukas, Alex, and Cantacessi, Cinzia (2014) RNA-seq reveals infection-induced gene expression changes in the snail intermediate host of the carcinogenic liver fluke, Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 8 (3). e2765. pp. 1-9.

Cantacessi, Cinzia, Giacomin, Paul, Croese, John, Zakrzewski, Martha, Sotillo, Javier, McCann, Leisa, Nolan, Matthew J., Mitreva, Makedonka, Krause, Lutz, and Loukas, Alex (2014) Impact of experimental hookworm infection on the human gut microbiota. Journal of Infectious Diseases, 210 (9). pp. 1431-1434.

Dougall, Annette M., Skwarczynski, Mariusz, Khoshnejad, Makan, Chandrudu, Saranya, Daly, Norelle L., Toth, Istvan, and Loukas, Alex (2014) Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine. Human Vaccines & Immunotherapeutics, 10 (2). pp. 399-409.

Phung, Luyen Thi, Loukas, Alex, Brindley, Paul J., Sripa, Banchob, and Laha, Thewarach (2014) Retrotransposon OV-RTE-1 from the carcinogenic liver fluke Opisthorchis viverrini: potential target for DNA-based diagnosis. Infection, Genetics and Evolution, 21. pp. 443-451.

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J., and Mulvenna, Jason (2014) Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10). pp. 7151-7163.

Thanasuwan, Sirikanda, Piratae, Supawadee, Brindley, Paul J., Loukas, Alex, Kaewkes, Sasithorn, and Laha, Thewarach (2014) Suppression of aquaporin, a mediator of water channel control in the carcinogenic liver fluke, Opisthorchis viverrini. Parasites & Vectors, 7 (1). 224. pp. 1-11.

Cantacessi, Cinzia, Seddon, Jennifer M., Miller, Terrence L., Leow, Chiuan Yee, Thomas, Laëtitia, Mason, Lyndel, Willis, Charlene, Walker, Giselle, Loukas, Alex, Gasser, Robin B., Jones, Malcolm K., and Hofmann, Andreas (2013) A genome-wide analysis of annexins from parasitic organisms and their vectors. Scientific Reports, 3. 2893. pp. 1-8.

Cantacessi, Cinzia, Prasopdee, Sattrachai, Sotillo, Javier, Mulvenna, Jason, Tesana, Smarn, and Loukas, Alex (2013) Coming out of the shell: building the molecular infrastructure for research on parasite-harbouring snails. PLoS Neglected Tropical Diseases, 7 (9). e2284. pp. 1-4.

Schwarz, Erich M., Korhonen, Pasi K., Campbell, Bronwyn E., Young, Neil D., Jex, Aaron R., Jabbar, Abdul, Hall, Ross S., Mondal, Alinda, Howe, Adina C., Pell, Jason, Hofmann, Andreas, Boag, Peter R., Zhu, Xing-Quan, Gregory, T. Ryan, Loukas, Alex, Williams, Brian A., Antoshechkin, Igor, Brown, C. Titus, Sternberg, Paul W., and Gasser, Robin B. (2013) The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus. Genome Biology, 14 (8). R89. pp. 1-18.

Ferreira, Ivana, Smyth, Danielle, Gaze, Soraya, Aziz, Ammar, Giacomin, Paul, Ruyssers, Nathalie, Artis, David, Laha, Thewarach, Navarro, Severine, Loukas, Alex, and McSorley, Henry J. (2013) Hookworm excretory/secretory products induce interleukin-4 (IL-4)+ IL-10+ CD4+ T cell responses and suppress pathology in a mouse model of colitis. Infection and Immunity, 81 (6). pp. 2104-2111.

Lima, Luciane Mota, Santos, Silvane Braga, Oliveira, Ricardo Riccio, Cardoso, Luciana Santos, Oliveira, Sergio Costa, Goes, Alfredo Miranda, Loukas, Alex, Carvalho, Edgar M., and Araujo, Maria Ilma (2013) Schistosoma antigens downmodulate the in vitro inflammatory response in individuals infected with human T cell lymphotropic virus type 1. Neuroimmunomodulation, 20 (4). pp. 233-238.

Croese, John, Gaze, Soraya T., and Loukas, Alex (2013) Changed gluten immunity in celiac disease by Necator americanus provides new insights into autoimmunity. International Journal for Parasitology, 43 (3-4). pp. 275-282.

Navarro, Severine, Ferreira, Ivana, and Loukas, Alex (2013) The hookworm pharmacopoeia for inflammatory diseases. International Journal for Parasitology, 43 (3-4). pp. 225-231.

Kline, Kevin, McCarthy, James S., Pearson, Mark, Loukas, Alex, and Hotez, Peter J. (2013) Neglected tropical diseases of oceania: review of their prevalence, distribution, and opportunities for control. PLoS Neglected Tropical Disease, 7 (1). e1755. pp. 1-9.

Loukas, Alex, and Good, Michael F. (2013) Back to the future for antiparasite vaccines? Expert Review of Vaccines, 12 (1). pp. 1-4.

Pearson, Mark S., Pickering, Darren, Ranjit, Najju, and Loukas, Alex (2013) Hookworm MEP-1 metalloproteases. In: Rawlings, Neil D., and Salvesen, Guy, (eds.) Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes, 1 . Elsevier, Amsterdam, The Netherlands, pp. 647-649.

Dougall, Annette M., Pearson, Mark S., and Loukas, Alex (2013) Na-APR-1 (aka necepsin-2). In: Rawlings, Neil D., and Salvesen, Guy, (eds.) Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes, 1 . Elsevier, Amsterdam, The Netherlands, pp. 113-118.

Cantacessi, Cinzia, Hofmann, Andreas, Pickering, Darren, Navarro, Severine, Mitreva, Makedonka, and Loukas, Alex (2013) TIMPs of parasitic helminths: a large-scale analysis of high-throughput sequence datasets. Parasites & Vectors, 6 (1). 156. pp. 1-11.

Hotez, Peter J., Diemert, David, Bacon, Kristina M., Beaumier, Coreen, Bethony, Jeffrey M., Bottazzi, Maria Elena, Brooker, Simon, Couto, Artur Roberto, da Silva Freire, Marcos, Homma, Akira, Lee, Bruce Y., Loukas, Alex, Loblack, Marva, Morel , Carlos Medicis, Oliveira, Rodrigo Correa, and Russell, Philip K. (2013) The human hookworm vaccine. Vaccine, 31 (Supplement 2). B227-B232.

Gaze, Soraya, McSorley, Henry J., Daveson, James, Jones, Di, Bethony, Jeffrey M., Oliveira, Luciana M., Speare, Richard, McCarthy, James S., Engwerda, Christian R., Croese, John, and Loukas, Alex (2012) Characterising the mucosal and systemic immune responses to experimental human hookworm infection. PLoS Pathogens, 8 (2). e1002520. pp. 1-11.

Cantacessi, Cinzia, Mulvenna, Jason, Young, Neil D., Kasny, Martin, Horak, Petr, Aziz, Ammar, Hofmann, Andreas, Loukas, Alex, and Gasser, Robin B. (2012) A deep exploration of the transcriptome and "excretory/secretory" proteome of adult Fascioloides magna. Molecular and Cellular Proteomics, 11 (11). pp. 1340-1353.

Barbosa Bafica, Aline Michelle, Santos Cardoso, Luciana, Oliveira, Sergio Costa, Loukas, Alex, Goes, Alfredo, Oliveira, Ricardo Riccio, Carvalho, Edgar M., and Araujo, Maria Ilma (2012) Changes in T-cell and monocyte phenotypes in vitro by Schistosoma mansoni antigens in cutaneous leishmaniasis patients. Journal of Parasitology Research, 2012. 520308. pp. 1-10.

Pearson, Mark S., Tribolet, Leon, Cantacessi, Cinzia, Periago, Maria Victoria, Adela Valerio, Maria, Jariwala, Amar R., Hotez, Peter, Diemert, David, Loukas, Alex, and Bethony, Jeffrey (2012) Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. Journal of Allergy and Clinical Immunology, 130 (1). pp. 13-21.

Osman, Asiah, Wang, Conan K., Winter, Anja, Loukas, Alex, Tribolet, Leon, Gasser, Robin B., and Hofmann, Andreas (2012) Hookworm SCP/TAPS protein structure: a key to understanding host–parasite interactions and developing new interventions. Biotechnology Advances, 30 (3). pp. 652-657.

Mairiang, Eimorn, Laha, Thewarach, Bethony, Jeffrey M., Thinkhamrop, Bandit, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Tesana, Smarn, Loukas, Alex, Brindley, Paul J., and Sripa, Banchob (2012) Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand. Parasitology International, 61 (1). pp. 208-211.

Mulvenna, Jason, Yonglitthipagon, Ponlapat, Sripa, Banchob, Brindley, Paul J., Loukas, Alex, and Bethony, Jeffrey M. (2012) Banking on the future: biobanking for "omics" approaches to biomarker discovery for Opisthorchis-induced cholangiocarcinoma in Thailand. Parasitology International, 61 (1). pp. 173-177.

Loukas, A., Ranjit, N., Pickering, D.A., and Pearson, M.S. (2012) Blood-feeding human hookworm proteases. In: Dunn, Ben, (ed.) Proteinases as Drug Targets. Royal Society of Chemistry, Cambridge, UK, pp. 186-198.

Senawong, Gulsiri, Laha, Thewarach, Loukas, Alex, Brindley, Paul J., and Sripa, Banchob (2012) Cloning, expression, and characterization of a novel Opisthorchis viverrini calcium-binding EF-hand protein. Parasitology International, 61 (1). pp. 94-100.

Sripa, Banchob, Thinkhamrop, Bandit, Mairiang, Eimorn, Laha, Thewarach, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Periago, Maria Victoria, Bhudhisawasdi, Vajarabhongsa, Yonglitthipagon, Ponlapat, Mulvenna, Jason, Brindley, Paul J., Loukas, Alex, and Bethony, Jeffrey M. (2012) Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 6 (5). e1654. pp. 1-9.

Pearson, Mark S., Pickering, Darren A., McSorley, Henry J., Bethony, Jeffrey M., Tribolet, Leon, Dougall, Annette M., Hotez, Peter J., and Loukas, Alex (2012) Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Neglected Tropical Diseases, 6 (3). e1564. pp. 1-10.

Sripa, Jittiyawadee, Brindley, Paul J., Sripa, Banchob, Loukas, Alex, Kaewkes, Sasithorn, and Laha, Thewarach (2012) Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis. Parasitology International, 61 (1). pp. 191-195.

Diemert, David J., Pinto, Antonio G., Freire, Janaina, Jariwala, Amar, Santiago, Helton, Hamilton, Robert G., Periago, Maria Victoria, Loukas, Alex, Tribolet, Leon, Mulvenna, Jason, Correa-Oliveira, Rodrigo, Hotez, Peter J., and Bethony, Jeffrey M. (2012) Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. Journal of Allergy and Clinical Immunology, 130 (1). pp. 169-176.

Cantacessi, Cinzia, Hofmann, Andreas, Young, Neil D., Broder, Ursula, Hall, Ross S., Loukas, Alex, and Gasser, Robin B. (2012) Insights into SCP/TAPS proteins of liver flukes based on large-scale bioinformatic analyses of sequence datasets. PLoS ONE, 7 (2). e31164. pp. 1-8.

Piratae, Supawadee, Tesana, Smarn, Jones, Malcolm K., Brindley, Paul J., Loukas, Alex, Lovas, Erica, Eursitthichai, Veerachai, Sripa, Banchob, Thanasuwan, Sirikanda, and Laha, Thewarach (2012) Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 6 (12). e1939. pp. 1-10.

Suttiprapa, Sutas, Matchimakul, Pitchaya, Loukas, Alex, Laha, Thewarach, Wongkham, Sopit, Kaewkes, Sasithorn, Brindley, Paul J., and Sripa, Banchob (2012) Molecular expression and enzymatic characterization of thioredoxin from the carcinogenic human liver fluke Opisthorchis viverrini. Parasitology International, 61 (1). pp. 101-106.

Skwarczynski, Mariusz, Dougall, Annette M., Khoshnejad, Makan, Chandrudu, Saranya, Pearson, Mark, Loukas, Alex, and Toth, Istvan (2012) Peptide-based subunit vaccine against hookworm infection. PLoS One, 7 (10). e46870. pp. 1-7.

Yonglitthipagon, Ponlapat, Pairojkul, Chawalit, Chamgramol, Yaovalux, Loukas, Alex, Mulvenna, Jason, Bethony, Jeffrey, Bhudhisawasdi, Vajarabhongsa, and Sripa, Banchob (2012) Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin binding phosphoprotein 50 in cholangiocarcinoma. Human Pathology, 43 (10). pp. 1719-1730.

Wang, Conan K., Broder, Ursula, Weeratunga, Saroja K., Gasser, Robin B., Loukas, Alex, and Hofmann, Andreas (2012) SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments. Bioinformatics, 28 (7). pp. 1026-1027.

Loukas, Alex, Gaze, Soraya, Pearson, Mark, Doolan, Denise, Felgner, Philip, Diemert, David, McManus, Donald P., Driguez, Patrick, and Bethony, Jeffrey (2012) Schistosomiasis vaccines: new approaches to antigen discovery and promising new candidates. In: Caffrey, Conor R., (ed.) Parasitic Helminths: targets, screens, drugs and vaccines. Drug Discovery in Infectious Diseases . Wiley-Blackwell, Weinheim, Germany, pp. 421-433.

Brinkman, Diane L., Aziz, Ammar, Loukas, Alex, Potriquet, Seymour, Jamie, and Mulvenna, Jason (2012) Venom proteome of the box jellyfish Chironex fleckeri. PLoS ONE, 7 (12). e47866. pp. 1-9.

Young, Neil D., Jex, Aaron R., Lo, Bo, Liu, Shiping, Yang, Linfeng, Xiong, Zijun, Li, Yingrui, Cantacessi, Cinzia, Hall, Ross S., Xu, Xun, Chen, Fangyuan, Wu, Xuan, Zerlotini, Adhemar, Oliveira, Guilherme, Hofmann, Andreas, Zhang, Guojie, Fang, Xiaodong, Kang, Yi, Campbell, Bronwyn E., Loukas, Alex, Ranganathan, Shoba, Rollinson, David, Rinaldi, Gabriel, Brindley, Paul J., Yang, Huanming, Wang, Jun, Wang, Jian, and Gasser, Robin B. (2012) Whole-genome sequence of Schistosoma haematobium. Nature Genetics, 44 (2). pp. 221-225.

Sripa, Banchob, Brindley, Paul J., Mulvenna, Jason, Laha, Thewarach, Smout, Michael J., Mairiang, Eimorn, Bethony, Jeffrey M., and Loukas, Alex (2012) The tumorigenic liver fluke Opisthorchis viverrini - multiple pathways to cancer. Trends in Parasitology, 28 (10). pp. 395-407.

Swain, Martin T., Larkin, Denis M., Caffrey, Conor R., Davies, Stephen J., Loukas, Alex, Skelly, Patrick J., and Hoffmann, Karl (2011) Schistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery. Trends in Parasitology, 27 (12). pp. 555-564.

Barbosa Bafica, Aline Michelle, Santos Cardoso, Luciana, Oliveria, Sergio Costa, Loukas, Alex, Varela, Giuseppe Tittoni, Oliveria, Ricardo Riccio, Bacellar, Olivia, Carvalho, Edgar Marcelino, and Araujo, Maria Ilma (2011) Schistosoma mansoni antigens alter the cytokine response in vitro during cutaneous leishmaniasis. Memorias do Instituto Oswaldo Cruz , 106 (7). pp. 856-863.

Rinaldi, Gabriel, Okatcha, Tunika I., Popratiloff, Anastas, Ayuk, Mary A., Suttiprapa, Sutas, Mann, Victoria H., Liang, Yung-san, Lewis, Fred A., Loukas, Alex, and Brindley, Paul J. (2011) Genetic manipulation of Schistosoma haematobium, the neglected schistosome. PLoS Neglected Tropical Disease, 5 (10). e1348. pp. 1-10.

Willis, Charlene, Wang, Conan K., Osman, Asiah, Simon, Anne, Pickering, Darren, Mulvenna, Jason, Riboldi-Tunicliffe, Alan, Jones, Malcolm K., Loukas, Alex, and Hoffman, Andreas (2011) Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm. PLoS ONE, 6 (10). e25369. pp. 1-10.

Smout, Michael J., Mulvenna, Jason P., Jones, Malcolm K., and Loukas, Alex (2011) Expression, refolding and purification of Ov-GRN-1, a granulin-like growth factor from the carcinogenic liver fluke, that causes proliferation of mammalian host cells. Protein Expression and Purification, 79 (2). pp. 263-270.

Sripa, Jittiyawadee, Pinlaor, Porntip, Brindley, Paul J., Sripa, Banchob, Kaewkes, Sasithorn, Robinson, Mark W., Young , Neil D., Gasser, Robin B., Loukas, Alex, and Laha, Thewarach (2011) RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini. Parasitology International, 60 (3). pp. 283-288.

Loukas, Alex, Gaze, Soraya, Mulvenna, Jason, Gasser, Robin, Brindley, Paul, Doolan, Denise, Bethony, Jeffrey, Jones, Malcolm, Gobert, Geoffrey, Drigues, Patrick, McManus, Donald, and Hotez, Peter (2011) Vaccinomics for the major blood feeding helminths of humans. OMICS: a Journal of Integrative Biology, 15 (11). pp. 567-577.

Sripa, Banchob, Bethony, Jeffrey, Sithithaworn, Paiboon, Kaewkes, Sasithorn, Mairiang, Eimorn, Loukas, Alex, Mulvenna, Jason, Laha, Thewarach, Hotez, Peter, and Brindley, Paul (2011) Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Tropica, 120 (Supp 1). S158-S168.

McSorley, Henry, Gaze, Soraya, Davidson, James, Jones, Dianne, Anderson, Robert P., Coulston, Andrew, Ruyssers, Nathalie, Speare, Richard, McCarthy, James, Engwerda, Christian R, Croese, John, and Loukas, Alex (2011) Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection. PLoS ONE, 6 (9). e24092. pp. 1-7.

Aziz, Ammar, Zhang, Wenbao, Li, Jun, Loukas, Alex, McManus, Donald, and Mulvenna, Jason (2011) Proteomic characterisation of Echinococcus granulosus hydatid cyst fluid from sheep, cattle and humans. Journal of Proteomics, 74 (9). pp. 1560-1572.

Daveson, A. James, Jones, Dianne M., Gaze Jangola, Soraya, McSorley, Henry, Clouston, Andrew, Pascoe, Andrew, Cooke, Sharon, Speare, Richard, Mcdonald, Graeme A., Anderson, Robert, McCarthy, James S., Loukas, Alex, and Croese, John (2011) Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial. PLoS ONE, 6 (3). e17366. pp. 1-9.

Campbell, Bronwyn E., Boag, Peter R., Hofmann, Andreas, Cantacessi, Cinzia, Wang, Conan K., Taylor, Paul, Hu, Min, Sindhu, Zia-ud-Din, Loukas, Alex, Sternberg, Paul W., and Gasser, Robin B. (2011) Atypical (RIO) protein kinases from Haemonchus contortus — Promise as new targets for nematocidal drugs. Biotechnology Advances, 29 (3). pp. 338-350.

Bethony, Jeffrey M., Cole, Rhea N., Guo, Xiaoti, Kamhawi, Shaden, Lightowlers, Marshall W., Loukas, Alex, Petri, William, Reed, Steven, Valenzuela, Jesus G., and Hotez, Peter J. (2011) Vaccines to combat the neglected tropical diseases. Immunological Reviews, 239 (1). pp. 237-270.

Smout, Michael J., Sripa, Banchob, Laha, Thewarach, Mulvenna, Jason, Gasser, Robin B. , Young, Neil D., Bethony, Jeffrey M., Brindley, Paul J., and Loukas, Alex (2011) Infection with the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular BioSystems, 7 (5). pp. 1367-1375.

Glanfield, Amber, McManus, Donald P., Smyth, Danielle J., Lovas, Erica M., Loukas, Alex, Gobert, Geoffrey N., and Jones, Malcolm K. (2010) A cytochrome b561 with ferric reductase activity from the parasitic blood fluke, Schistosoma japonicum. PLoS Neglected Tropical Diseases, 4 (11). e884. pp. 1-11.

Smout, Michael J., Kotze, Andrew C., McCarthy, James S., and Loukas, Alex (2010) A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility. PLoS Neglected Tropical Disease, 4 (11). e885. pp. 1-10.

Hotez, Peter J., Bethony, Jeffrey M., Diemert, David J., Pearson, Mark, and Loukas, Alex (2010) Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews Microbiology , 8 (11). pp. 814-826.

Young, Neil D., Jex, Aaron R., Cantacessi, Cinzia, Campbell, Bronwyn E., Laha, Thewarach, Sohn, Woon-Mok, Sripa, Banchob , Loukas, Alex, Brindley, Paul J., and Gasser, Robin B. (2010) Progress on the transcriptomics of carcinogenic liver flukes of humans - unique biological and biotechnological prospects. Biotechnology Advances, 28 (6). pp. 859-870.

Amante, Fiona H., Haque, Ashraful, Stanley, Amanda C., de Labastida Rivera, Fabian, Randall, Louise M., Wilson, Yana A., Yeo , Gladys, Pieper, Christian, Crabb, Brendan S., de Koning-Ward, Tania F., Lundie, Rachel J., Good, Michael F., Pinzon-Charry, Alberto, Pearson, Mark S., Duke, Mary G., McManus, Donald P., Loukas, Alex, Hill, Geoff R., and Engwerda, Christian R. (2010) Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. Journal of Immunology, 185 (6). pp. 3632-3642.

Loukas, Alex, Spithill, Terry, and Cowman, Alan (2010) Editorial: ICOPA down under. International Journal for Parasitology, 40 (10). p. 1107.

Pearson, Mark S., Ranjit, Najju, and Loukas, Alex (2010) Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasites. Biological Chemistry, 391 (8). pp. 901-911.

McSorley, H.J., and Loukas, A. (2010) The immunology of human hookworm infections. Parasite Immunology, 32 (8). pp. 549-559.

Young, Neil D., Campbell, Bronwyn E., Hall, Ross S., Jex, Aaron R., Cantacessi, Cinzia , Laha, Thewarach, Sohn, Woon-Mok , Sripa, Banchob , Loukas, Alex, Brindley, Paul J., and Gasser, Robin B. (2010) Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 4 (6). e719. pp. 1-14.

Pearson, Mark S., Pickering, Darren A., Tribolet, Leon, Cooper, Leanne, Mulvenna, Jason, Oliveira, Luciana M., Bethony, Jeffrey M., Hotez, Peter J., and Loukas, Alex (2010) Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm Infection and schistosomiasis. Journal of Infectious Diseases, 201 (10). pp. 1561-1569.

Cantacessi, Cinzia , Mitreva, Makedonka , Jex, Aaron R., Young, Neil D., Campbell, Bronwyn E., Hall, Ross S., Doyle, Maria A., Ralph, Stuart A., Rabelo, Elida M., Ranganathan, Shoba , Sternberg, Paul W., Loukas, Alex, and Gasser, Robin B. (2010) Massively parallel sequencing and analysis of the Necator americanus transcriptome. PLoS Neglected Tropical Diseases, 4 (5). e684. pp. 1-11.

Cantacessi, Cinzia, Campbell, Bronwyn E., Young, Neil D., Jex, Aaron R., Hall, Ross S., Presidente, Paul J.A., Zawadzki, Jodi L., Zhong, Weiwei, Aleman-Meza, Boanerges, Loukas, Alex, Sternberg, Paul W., and Gasser, Robin B. (2010) Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortus. BMC Genomics, 11. 266. pp. 1-14.

Tran, Mai H., Freitas, Tori C., Cooper, Leanne, Gaze, Soraya, Gatton, Michelle L., Jones, Malcolm K., Lovas, Erica, Pearce, Edward J., and Loukas, Alex (2010) Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover. PLoS Pathogens, 6 (4). e1000840. pp. 1-10.

Mulvenna, Jason, Moertel, Luke, Jones, Malcolm K., Nawaratna, Sujeevi, Lovas, Erica M., Gobert, Geoffrey N., Colgrave, Michelle, Jones, Alun, Loukas, Alex, and McManus, Donald P. (2010) Exposed proteins of the Schistosoma japonicum tegument. International Journal for Parasitology, 40 (5). pp. 543-554.

Zhan, Bin, Perally, Samirah, Brophy, Peter M., Xue, Jian, Goud, Gaddam, Liu, Sen, Deumic, Vehid, de Oliveira, Luciana M., Bethony, Jeffrey, Bottazzi, Maria Elena, Jiang, Desheng, Gillespie, Portia, Xiao, Shu-hua, Gupta, Richi, Loukas, Alex, Ranjit, Najju, Lustigman, Sara, Oksov, Yelena, and Hotez, Peter (2010) Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infection and Immunity, 78 (4). pp. 1552-1563.

Mulvenna, Jason, Sripa, Banchob, Brindley, Paul J., Gorman, Jeffrey, Jones, Malcolm K., Colgrave, Michelle L., Jones, Alun, Nawaratna, Sujeevi, Laha, Thewarach, Suttiprapa, Sutas, Smout, Michael J., and Loukas, Alex (2010) The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini. Proteomics, 10 (5). pp. 1063-1078.

Ruyssers, Nathalie E., De Winter, Benedicte Y., De Man, Joris G., Ruyssers, Natacha D., Van Gils, Ann J., Loukas, Alex, Pearson, Mark S., Weinstock, Joel V., Pelckmans, Paul A., and Moreels, Tom G. (2010) Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice. World Journal of Gastroenterology, 16 (6). pp. 703-712.

Gobert, Geoffrey N., Tran, Mai H., Moertel, Luke, Mulvenna, Jason, Jones, Malcolm K., McManus, Donald P., and Loukas, Alex (2010) Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. PLoS Neglected Tropical Disease, 4 (2). e600. pp. 1-13.

Driguez, Patrick, Doolan, Denise L., Loukas, Alex, Felgner, Philip L., and McManus, Donald P. (2010) Schistosomiasis vaccine discovery using immunomics. Parasites & Vectors, 3 (1). 4. pp. 1-5.

Sripa, Banchob, Mairiang, Eimorn, Thinkhamrop, Bandit, Laha, Thewarach, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Tessana, Smarn, Loukas, Alex, Brindley, Paul J., and Bethony, Jeffrey M. (2009) Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6. Hepatology, 50 (4). pp. 1273-1281.

Smout, Michael J., Laha, Thewarach, Mulvenna, Jason, Sripa, Banchob, Suttiprapa, Sutas, Jones, Alun, Brindley, Paul J., and Loukas, Alex (2009) A granulin-like growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, promotes proliferation of host cells. PLoS Pathogens, 5 (10). e1000611. pp. 1-16.

Pearson, Mark S., Bethony, Jeffrey M., Pickering, Darren A., de Oliveira, Luciana M., Jariwala, Amar, Santiago, Helton, Miles, Aaron P., Zhan, Bin, Jiang, Desheng, Ranjit, Najju, Mulvenna, Jason, Tribolet, Leon, Plieskatt, Jordan, Smith, Tracey, Bottazzi, Maria Elena, Jones, Kathryn, Keegan, Brian, Hotez, Peter J., and Loukas, Alex (2009) An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB Journal, 23 (9). pp. 3009-3017.

Pinheiro, C.S., Staub, O., Mulvenna, J., Loukas, A., Jones, M.K., and Rabelo, E.M. (2009) Characterization and binding affinities of SmLANP: a new Schistosoma mansoni member of the ANP32 family of regulatory proteins. Molecular and Biochemical Parasitology, 165 (2). pp. 95-102.

Ruyssers, Nathalie E., De Winter, Benedicte Y., De Man, Joris G., Loukas, Alex, Pearson, Mark, Weinstock, Joel V., Van den Bossche, Rita M., Martinet, Wim, Pelckmans, Paul A., and Moreels, Tom G. (2009) Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice. Inflammatory Bowel Diseases, 15 (4). pp. 491-500.

Ranjit, Najju, Zhan, Bin, Hamilton, Brett, Stenzel, Deborah, Lowther, Jonathan, Pearson, Mark, Gorman, Jeffrey, Hotez, Peter, and Loukas, Alex (2009) Proteolytic degradation of hemoglobin in the intestine of the human hookworm necator Americanus. Journal of Infectious Diseases, 199 (6). pp. 904-912.

Pinlaor, Porntip, Kaewpitoon, Natthawut, Laha, Thewarach, Sripa, Banchob, Kaewkes, Sasithorn, Morales, Maria E., Mann, Victoria H., Parriott, Sandi K., Suttiprapa, Sutas, Robinson, Mark W., To, Joyce, Dalton, John P., Loukas, Alex, and Brindley, Paul J. (2009) Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini. PLoS Neglected Tropical Disease, 3 (3). e398. pp. 1-15.

Datu, Bennett J.D., Loukas, Alex, Cantacessi, Cinzia, O'Donoghue, Peter, and Gasser, Robin B. (2009) Investigation of the regulation of transcriptional changes in Ancylostoma caninum larvae following serum activation, with a focus on the insulin-like signalling pathway. Veterinary Parasitology, 159 (2). pp. 139-148.

Cantacessi, C., Loukas, A., Campbell, B.E., Mulvenna, J., Ong, E.K., Zhong, W., Sternberg, P.W., Otranto, D., and Gasser, R.B. (2009) Exploring transcriptional conservation between Ancylostoma caninum and Haemonchus contortus by oligonucleotide microarray and bioinformatic analyses. Molecular and Cellular Probes, 23 (1). pp. 1-9.

Mulvenna, Jason, Hamilton, Brett, Nagaraj, Shivashankar H., Smyth, Danielle, Loukas, Alex, and Gorman, Jeffrey J. (2009) Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum. Molecular and Cellular Proteomics, 8 (1). pp. 109-121.

Rabelo, Elida M., Hall, Ross S., Loukas, Alex, Cooper, Leanne, Hu, Min, Ranganathan, Shoba, and Gasser, Robin B. (2009) Improved insights into the transcriptomes of the human hookworm Necator americanus: fundamental and biotechnological implications. Biotechnology Advances, 27 (2). pp. 122-132.

Suttiprapa, Sutas, Mulvenna, Jason, Huong, Ngo Thi, Pearson, Mark S., Brindley, Paul J., Laha, Thewarach, Wongkham, Sopit, Sripa, Banchob, and Loukas, Alex (2009) Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: functional expression, immunolocalization and subsite specificity. International Journal of Biochemistry & Cell Biology, 41 (5). pp. 1148-1156.

Cantacessi, C., Campbell, B.E., Visser, A., Geldhof, P., Nolan, M.J., Nisbet, A.J., Matthews, J.B., Loukas, A., Hofmann, A., Otranto, D., Sternberg, P.W., and Gasser, R.B. (2009) A portrait of the "SCP/TAPS" proteins of eukaryotes: developing a framework for fundamental research and biotechnological outcomes. Biotechnology Advances, 27 (4). pp. 376-388.

Teixeira-Carvalho, Andréa, Fujiwara, Ricardo T., Stemmy, Erik J., Olive, Denise, Damsker, Jesse M., Loukas, Alex, Correa-Oliveira, Rodrigo, Constant, Stephanie L., and Bethony, Jeffrey M. (2008) Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Infection and Immunity, 76 (12). pp. 5810-5816.

Jones, Malcolm K., Bong, Sze How, Green, Kathryn M., Holmes, Philadelphia, Duke, Mary, Loukas, Alex, and McManus, Donald P. (2008) Correlative and dynamic imaging of the hatching biology of Schistosoma japonicum from eggs prepared by high pressure freezing. PLoS Neglected Tropical Diseases, 2 (11). e334. pp. 1-11.

Campbell, B.E., Nisbet, A.J., Mulvenna, J., Loukas, A., and Gasser, R.B. (2008) Molecular and phylogenetic characterization of cytochromes c from Haemonchus contortus and Trichostrongylus vitrinus (Nematoda: Trichostrongylida). Gene, 424 (1-2). pp. 121-129.

Suttiprapa, Sutas, Loukas, Alex, Laha, Thewarach, Wongkham, Sopit, Kaewkes, Sasithorn, Gaze, Soraya, Brindley, Paul J., and Banchob, Sripa (2008) Characterization of the antioxidant enzyme, thioredoxin peroxidase, from the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular and Biochemical Parasitology, 160 (2). pp. 116-122.

Hotez, Peter J., Bethony, Jeffrey M., Oliveira, Sergio, Brindley, Paul J., and Loukas, Alex (2008) Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines, 7 (6). pp. 745-752.

Ranjit, Najju, Zhan, Bin, Stenzel, Deborah J., Mulvenna, Jason, Fujiwara, Ricardo, Hotez, Peter, and Loukas, Alex (2008) A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Molecular and Biochemical Parasitology, 160 (2). pp. 90-99.

Jones, Malcolm K., Lustigman, Sara, and Loukas, Alex (2008) Tracking the odysseys of juvenile schistosomes to understand host interactions. PLoS Neglected Tropical Disease, 2 (7). e257. pp. 1-2.

Loukas, Alex, and Bethany, Jeffrey M. (2008) New drugs for an ancient parasite. Nature Medicine, 14 (4). pp. 365-367.

Kaewpitoon, Natthawut, Laha, Thewarach, Kaewkes, Sasithorn, Yongvanit, Puangrat, Brindley, Paul, Loukas, Alex, and Sripa, Banchob (2008) Characterization of cysteine proteases from the carcinogenic liver fluke, Opisthorchis viverrini. Parasitology Research, 102 (4). pp. 757-764.

Bethony, Jeffrey M., and Loukas, Alex (2008) The Schistosomiasis research agenda: what now? PLoS Neglected Tropical Disease, 2 (2). e207. pp. 1-2.

Datu, Bennett J.D., Gasser, Robin, Nagaraj, Shivashankar H., Ong, Eng K., O'Donoghue, Peter, McInnes, Russell, Ranganathan, Shoba, and Loukas, Alex (2008) Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larva. PLoS Neglected Tropical Diseases, 2 (1). e130. pp. 1-15.

Gasser, R.B., Cantacessi, C., and Loukas, A. (2008) DNA technological progress toward advanced diagnostic tools to support human hookworm control. Biotechnology Advances, 26 (1). pp. 35-45.

Campbell, Bronwyn E., Nagaraj, Shivashankar H., Hu, Min, Zhong, Weiwei, Sternberg, Paul W., Ong, Eng K., Loukas, Alex, Ranganathan, Shoba, Beveridge, Ian, McInnes, Russell L., Hutchinson, Gareth W., and Gasser, Robin B. (2008) Gender-enriched transcripts in Haemonchus contortus: predicted functions and genetic interactions based on comparative analyses with Caenorhabditis elegans. International Journal for Parasitology, 38 (1). pp. 65-83.

Xiao, Shuhua, Zhan, Bin, Xue, Jian, Goud, Gaddam Narsa, Loukas, Alex, Liu, Yueyuan, Williamson, Angela, Liu, Sen, Deumic, Vehid, and Hotez, Peter (2008) The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Experimental Parasitology, 118 (1). pp. 32-40.

Laha, Thewarach, Sripa, Jittiyawadee, Sripa, Banchob, Pearson, Mark, Tribolet, Leon, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Brindley, Paul J., and Loukas, Alex (2008) Asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and its potential for serodiagnosis. International journal of infectious diseases, 12 (6). e49-e59.

Bethony, Jeffrey M., Diemert, David J., Oliveira, Sergio Costa, and Loukas, Alex (2008) Can schistosomiasis really be consigned to history without a vaccine? Vaccine, 26 (27-28). pp. 3373-3376.

McManus, Donald P., and Loukas, Alex (2008) Current status of vaccines for schistosomiasis. Clinical Microbiology Reviews, 21 (1). pp. 225-242.

Huang, Cui-Qin, Gasser, Robin B., Cantacessi, Cinzia, Nisbet, Alaisdar J., Zhong, Weiwei, Sternberg, Paul W., Loukas, Alex, Mulvenna, Jason, Lin, Rui-Qing, Chen, Ning, and Zhu, Xing-Quan (2008) Genomic-bioinformatic analysis of transcripts enriched in the third-stage larva of the parasitic nematode Ascaris suum. PLoS Neglected Tropical Diseases, 2 (6). e246. pp. 1-12.

Don, Tegan A., Bethony, Jeffrey M., and Loukas, Alex (2008) Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections. International Journal of Infectious Diseases, 12 (6). e39-e47.

Ruyssers, Nathalie E., De Winter, Benedicte Y., De Man, Joris G., Loukas, Alex, Herman, Arnold G., Pelckmans, Paul A., and Moreels, Tom G. (2008) Worms and the treatment of inflammatory bowel disease: are molecules the answer? Journal of Immunology Research, 2008. 567314. pp. 1-7.

Pearson, M.S, McManus, D.P., Smyth, D.J., Jones, M.K., Sykes, A.M., and Loukas, A. (2007) Cloning and characterization of an orphan seven transmembrane receptor from Schistosoma mansoni. Parasitology, 134 (14). pp. 2001-2008.

Sripa, Banchob, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Mairiang, Eimorn, Laha, Thewarach, Smout, Michael, Pairojkul, Chawalit, Bhudhisawasdi, Vajaraphongsa, Tesana, Smarn, Thinkamrop, Bandit, Bethony, Jeffrey M., Loukas, Alex, and Brindley, Paul J. (2007) Liver fluke induces Cholangiocarcinoma. PLoS Medicine, 4 (7). 201. pp. 1148-1155.

Loukas, Alex, Tran, Mai, and Pearson, Mark S. (2007) Schistosome membrane proteins as vaccines. International Journal for Parasitology, 37 (3-4). pp. 257-263.

Laha, Thewarach, Pinlaor, Porntip, Mulvenna, Jason, Sripa, Banchob, Sripa, Manop, Smout, Michael J., Gasser, Robin B., Brindley, Paul J., and Loukas, Alex (2007) Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini. BMC Genomics, 8. 189. pp. 1-15.

Tran, Mai H., Pearson, Mark S., Bethony, Jeffrey M., Smyth, Danielle J., Jones, Malcolm K., Duke, Mary, Don, Tegan A., McManus, Donald P., Correa-Oliveira, Rodrigo, and Loukas, Alex (2006) Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nature Medicine, 12 (7). pp. 835-840.

Rosenzvit, Mara C., Zhang, Wenbao, Motazedian, Hossein, Smyth, Danielle, Pearson, Mark, Loukas, Alex, Jones, Malcolm K., and McManus, Donald P. (2006) Identification of membrane-bound and secreted proteins from Echinococcus granulosus by signal sequence trap. International Journal for Parasitology, 36 (1). pp. 123-130.

Bethony, Jeffrey, Loukas, Alex, Smout, Michael, Brooker, Simon, Mendez, Susana, Plieskatt, Jordan, Goud, Gaddam, Bottazzi, Maria Elena, Zhan, Bin, Wang, Yan, Williamson, Angela, Lustigman, Sara, Correa-Oliveira, Rodrigo, Xiao, Shuhua, and Hotez, Peter J. (2005) Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB Journal, 19 (12). pp. 1743-1745.

Pearson, Mark S., McManus, Donald P., Smyth, Danielle J., Lewis, Fred A., and Loukas, Alex (2005) In vitro and in silico analysis of signal peptides from the human blood fluke, Schistosoma mansoni. FEMS Immunology and Medical Microbiology, 45 (2). pp. 201-11.

Smyth, Danielle, McManus, Donald P., Smout, Michael J., Laha, Thewarach, Zhang, Wenbao, and Loukas, Alex (2003) Isolation of cDNAs encoding secreted and transmembrane proteins from Schistosoma mansoni by a signal sequence trap method. Infection and Immunity, 71 (5). pp. 2548-2554.

laha, Thewarch, Brindley, Paul J., Smout, Michael J., Verity, Christiana K., McManus, Donald P., and Loukas, Alex (2002) Reverse transcriptase activity and untranslated region sharing of a new RTE-like, non-long terminal repeat retrotransposon from the human blood fluke, Schistosoma japonicum. International Journal for Parasitology, 32 (9). pp. 1163-1174.