Helminths and intestinal flora team up to improve gut health

Giacomin, Paul, Agha, Zainab, and Loukas, Alex (2016) Helminths and intestinal flora team up to improve gut health. Trends in Parasitology, 32 (9). pp. 664-666.

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Abstract

Inflammatory bowel diseases (IBD) are associated with impaired intestinal barrier function, chronic inflammation, and microbial dysbiosis. In a recent publication in Science, Ramanan et al. used murine and human studies to demonstrate that infections with gastrointestinal helminths can protect against IBD by provoking immune responses that alter the balance of commensal and pathogenic bacteria in the intestine.

Item ID: 44969
Item Type: Article (Short Note)
ISSN: 1471-5007
Keywords: helminth; microbiota; hygiene hypothesis; inflammatory bowel disease
Funders: National Health and Medical Research Council (NHMRC), Queensland Government Department of Science, Information Technology and Innovation (DSITI)
Date Deposited: 11 Aug 2016 02:28
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920105 Digestive System Disorders @ 100%
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