Liver fluke induces Cholangiocarcinoma

Sripa, Banchob, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Mairiang, Eimorn, Laha, Thewarach, Smout, Michael, Pairojkul, Chawalit, Bhudhisawasdi, Vajaraphongsa, Tesana, Smarn, Thinkamrop, Bandit, Bethony, Jeffrey M., Loukas, Alex, and Brindley, Paul J. (2007) Liver fluke induces Cholangiocarcinoma. PLoS Medicine, 4 (7). 201. pp. 1148-1155.

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Abstract

[Extract] Liver fluke infection caused by Opisthorchis viverrini, O. felineus, and Clonorchis sinensis is a major public health problem in East Asia and Eastern Europe. Currently, more than 600 million people are at risk of infection with these trematodes [1]. O. viverrini is endemic in Southeast Asian countries, including Thailand, Lao People's Democratic Republic, Vietnam, and Cambodia [2], and C. sinensis infection is common in rural areas of Korea and China. Opisthorchiasis has been extensively studied in Thailand, where an estimated 6 million people are infected with the liver fluke (calculated from overall 9.4% prevalence within the population in 2001) [3].

Item ID: 35059
Item Type: Article (Research - C1)
ISSN: 1549-1676
Keywords: cancer, liver fluke, thailand, cholangiocarcinoma
Additional Information:

© 2007 Sripa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Funders: National Institute of Allergy and Infectious Disease (NIAID), Sandler Family Foundation
Projects and Grants: NIAID 1UO1 AI065871
Date Deposited: 06 Nov 2014 01:06
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology @ 60%
11 MEDICAL AND HEALTH SCIENCES > 1112 Oncology and Carcinogenesis > 111201 Cancer Cell Biology @ 30%
11 MEDICAL AND HEALTH SCIENCES > 1112 Oncology and Carcinogenesis > 111202 Cancer Diagnosis @ 10%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920102 Cancer and Related Disorders @ 50%
92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920105 Digestive System Disorders @ 40%
97 EXPANDING KNOWLEDGE > 970111 Expanding Knowledge in the Medical and Health Sciences @ 10%
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