Mollusk allergy: Not simply cross-reactivity with crustacean allergens

Kamath, Sandip D., Liu, Tiange, Giacomin, Paul, Loukas, Alex, Navarro, Severine, and Lopata, Andreas L. (2022) Mollusk allergy: Not simply cross-reactivity with crustacean allergens. Allergy, 77 (10). pp. 3127-3130.

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[Extract] To the Editor,

Mollusk allergy is commonly thought of as clinical cross-reactivity after primary sensitization to shrimps, other crustaceans, or mites. Tropomyosin is the major allergen, with primary IgE sensitization in 70% of all shellfish allergies. A high frequency of IgE and basophil reactivity to several mollusk allergens is seen in crustacean and mite-sensitized patients. It is still unclear, however, whether mollusks are capable of producing primary allergic sensitization, or whether IgE reactivity is based solely on cross-reactive crustacean-specific antibodies.

Item ID: 76400
Item Type: Article (Commentary)
ISSN: 1398-9995
Keywords: allergy, crustacean, mollusk, shellfish, tropomyosin
Copyright Information: © 2022 The Authors. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Funders: National Health and Medical Research Council (NHMRC)
Projects and Grants: NHMRC GNT1124143
Date Deposited: 07 Mar 2023 01:51
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320401 Allergy @ 100%
SEO Codes: 20 HEALTH > 2001 Clinical health > 200104 Prevention of human diseases and conditions @ 100%
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