Helminth coinfection and COVID-19: an alternate hypothesis

Hays, Russell, Pierce, Doris, Giacomin, Paul, Loukas, Alex, Bourke, Peter, and McDermott, Robyn (2020) Helminth coinfection and COVID-19: an alternate hypothesis. PLoS Neglected Tropical Diseases, 14 (8). e0008628.

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Abstract

[Extract] In their recently published commentary, Bradbury and colleagues [1] drew attention to the possible negative interactions between helminth infection and COVID-19 severity in helminth-endemic regions. Helminth infections are known to be powerful modulators of the human immune response, and numerous studies now highlight the effects this may have on human infectious, inflammatory, and metabolic diseases. We believe, however, that any interaction between pre-existing helminth infection and the subsequent severity of COVID-19 need not necessarily be a negative one, and theoretical and empirical evidence suggests that helminths may indeed have a mitigating effect.

Item ID: 64372
Item Type: Article (Commentary)
ISSN: 1935-2735
Copyright Information: © 2020 Hays et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Date Deposited: 16 Sep 2020 07:41
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320211 Infectious diseases @ 50%
42 HEALTH SCIENCES > 4202 Epidemiology > 420299 Epidemiology not elsewhere classified @ 50%
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