Allen, Tammy, Castellanos Reynosa, Maria, Giacomin, Paul, Karunaweera, Nadira D., Kupz, Andreas, Carlos LoL, Juan, Sharma, Dileep, Sikder, Suchandan, Tedla, Bemnet, van Eijk, Liza, Vojisavljevic, Danica, Zhao, Guangzu, and Pai, Saparna (2024) Next-Generation Vaccines for Tropical Infectious Diseases. International Journal of Infectious Diseases, 143. 107014.

Strugnell, Richard A., Newton, Hayley J., and Kupz, Andreas (2024) Survival strategies of intracellular bacterial pathogens. In: Tang, Yi-Wei, Hindiyeh, Musa, Liu, Dongyou, Sails, Andrew, Spearman, Paul, and Zhang, Jingren, (eds.) Molecular Medical Microbiology. Elsevier, London, United Kingdom, pp. 457-488.

McCulloch, Timothy R., Rossi, Gustavo R., Miranda-Hernandez, Socorro, Valencia-Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J., Krause, Andrew, Zacchi, Lucia F., Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J., and Souza-Fonseca-Guimaraes, Fernando (2024) The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology and Cell Biology, 102 (8). pp. 721-733.

Valencia-Hernandez, Ana Maria, Zhao, Guangzu, Miranda-Hernandez, Socorro, Segura-Cerda, Cristian Alfredo, Pedroza-Roldan, Cesar, Seifert, Julia, Aceves-Sanchez, Michel de Jesus, Burciaga-Flores, Mirna, Gutierrez-Ortega, Abel, del Pozo-Ramos, Lidia Maria, Flores-Valdez, Mario Alberto, and Kupz, Andreas (2024) A second-generation recombinant BCG strain combines protection against murine tuberculosis with an enhanced safety profile in immunocompromised hosts. Vaccine, 42. 126291.

Enjeti, Aditya, Sathkumara, Harindra Darshana, and Kupz, Andreas (2023) Impact of the gut-lung axis on tuberculosis susceptibility and progression. Frontiers in Microbiology, 14. 1209932. pp. 1-8.

Puri, Munish, Miranda-Hernandez, Socorro, Subbian, Selvakumar, and Kupz, Andreas (2023) Repurposing mucosal delivery devices for live attenuated tuberculosis vaccines. Frontiers in Immunology, 14. 1159084.

Pazoki, Hossein, Mirjalali, Hamed, Niyyati, Maryam, Seyed Tabaei, Seyed Javad, Mosaffa, Nariman, Shahrokh, Shabnam, Asadzadeh Ahdaei, Hamid, Kupz, Andreas, and Zali, Mohammad Reza (2023) Toxoplasma gondii profilin induces NLRP3 activation and IL-1β production/secretion in THP-1 cells. Microbial Pathogenesis, 180. 106120.

Wang, Nancy, Scott, Timothy A., Kupz, Andreas, Shreenivas, Meghanashree M., Peres, Newton G., Hocking, Dianna M., Yang, Chenying, Jebeli, Leila, Beattie, Lynette, Groom, Joanna R., Pierce, Thomas P., Wakim, Linda M., Bedoui, Sammy, and Strugnell, Richard A. (2023) Vaccine-induced inflammation and inflammatory monocytes promote CD4+ T cell-dependent immunity against murine salmonellosis. PLoS Pathogens, 19 (9). e1011666.

Karunathilaka, Amali, Halstrom, Samuel, Price, Patricia, Holt, Michael, Lutzky, Viviana P., Doolan, Denise L., Kupz, Andreas, Bell, Scott C., Thomson, Rachel M., Miles, John J., and Ratnatunga, Champa N. (2022) CD161 expression defines new human γδ T cell subsets. Immunity & Ageing, 19. 11.

Ratnatunga, Champa N., Tungatt, Katie, Proietti, Carla, Halstrom, Sam, Holt, Michael R., Lutzky, Viviana P., Price, Patricia, Doolan, Denise L., Bell, Scott C., Field, Matt A., Kupz, Andreas, Thomson, Rachel M., and Miles, John J. (2022) Characterizing and correcting immune dysfunction in non-tuberculous mycobacterial disease. Frontiers in Immunology, 13. 1047781.

Nisa, Annuurun, Kipper, Franciele C., Panigrahy, Dipak, Tiwari, Sangeeta, Kupz, Andreas, and Subbian, Selvakumar (2022) Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection. American Journal of Physiology: cell physiology, 323 (5). C1444-C1474.

Muruganandah, Visai, and Kupz, Andreas (2022) Immune responses to bacterial lung infections and their implications for vaccination. International Immunology, 34 (5). pp. 231-248.

Flores-Valdez, Mario Alberto, Kupz, Andreas, and Subbian, Selvakumar (2022) Recent Developments in Mycobacteria-Based Live Attenuated Vaccine Candidates for Tuberculosis. Biomedicines, 10 (11). 2749.

Peres, Newton G., Wang, Nancy, Whitney, Paul, Engel, Sven, Shreenivas, Meghanashree M., Comerford, Ian, Hocking, Dianna M., Erazo, Anna B., Forster, Irmgard, Kupz, Andreas, Gebhardt, Thomas, McColl, Shaun R., McSorley, Stephen J., Bedoui, Sammy, and Strugnell, Richard A. (2021) CD4+ T cell immunity to Salmonella is transient in the circulation. PLoS Pathogens, 17 (10). e1010004.

Smith, Nicholas C., Goulart, Cibelly, Hayward, Jenni A., Kupz, Andreas, Miller, Catherine M., and van Dooren, Giel C. (2021) Control of human toxoplasmosis. International Journal for Parasitology, 51 (2-3). pp. 95-121.

Husain, Aliabbas A., Kupz, Andreas, and Kashyap, Rajpal S. (2021) Controlling the drug-resistant tuberculosis epidemic in India: challenges and implications. Epidemiology and Health, 43. e2021022.

Heijmenberg, Isis, Husain, Aliabbas, Sathkumara Mudiyanse, Harindra D., Muruganandah, Visai, Seifert, Julia, Miranda-Hernandez, Socorro, Kashyap, Rajpal Singh, Field, Matt A., Krishnamoorthy, Gopinath, and Kupz, Andreas (2021) ESX-5-targeted export of ESAT-6 in BCG combines enhanced immunogenicity & efficacy against murine tuberculosis with low virulence and reduced persistence. Vaccine, 39 (50). pp. 7265-7276.

Khudhair, Zainab, Alhallaf, Rafid, Eichenberger, Ramon M., Whan, Jen, Kupz, Andreas, Field, Matt, Krause, Lutz, Wilson, David T., Daly, Norelle L., Giacomin, Paul, Sotillo, Javier, and Loukas, Alex (2021) Gastrointestinal helminth infection improves insulin sensitivity, decreases systemic inflammation, and alters the composition of gut microbiota in distinct mouse models of Type 2 diabetes. Frontiers in Endocrinology, 11. 606530.

Ruscher, Roland, and Kupz, Andreas (2021) Home-o-static slowficiency. Science, 371 (6524). p. 23.

Kupz, Andreas (2021) Live attenuated vaccines for tuberculosis. The Biochemist, 43 (4).

Adegboye, Oyelola, Field, Matt A., Kupz, Andreas, Pai, Saparna, Sharma, Dileep, Smout, Michael J., Wangchuk, Phurpa, Wong, Yide, and Loiseau, Claire (2021) Natural-product-based solutions for tropical infectious diseases. Clinical Microbiology Reviews, 34 (4). e00348-20.

Kupz, Andreas (2021) Tuberculosis kills as many people each year as COVID-19. It’s time we found a better vaccine. The Conversation, 15 January 2021.

Sathkumara, Harindra D., Eaton, Janet L., Field, Matt A., Govan, Brenda L., Ketheesan, Natkunam, and Kupz, Andreas (2021) A murine model of tuberculosis/type 2 diabetes comorbidity for investigating the microbiome, metabolome and associated immune parameters. Animal Models and Experimental Medicine, 4 (2). pp. 181-188.

Sathkumara, Harindra D., Hansen, Karyina, Miranda-Hernandez, Socorro, Govan, Brenda, Rush, Catherine M., Henning, Lars, Ketheesan, Natkunam, and Kupz, Andreas (2020) Disparate effects of metformin on Mycobacterium tuberculosis infection in diabetic and nondiabetic mice. Antimicrobial Agents and Chemotherapy, 65 (1). e01422-20.

Schmidt, Casey A., Wilson, David T., Cooke, Ira, Potriquet, Jeremy, Tungatt, Katie, Muruganandah, Visai, Boote, Chloe, Kuek, Felicity, Miles, John J., Kupz, Andreas, Ryan, Stephanie, Loukas, Alex, Bansal, Paramjit S., Takjoo, Rozita, Miller, David J., Peigneur, Steve, Tytgat, Jan, and Daly, Norelle (2020) Identification and characterization of a peptide from the stony coral Heliofungia actiniformis. Journal of Natural Products, 83 (11). pp. 3454-3463.

Alim, Mohammad Abdul, Kupz, Andreas, Sikder, Suchandan, Rush, Catherine, Govan, Brenda, and Ketheesan, Natkunam (2020) Increased susceptibility to Mycobacterium tuberculosis infection in a diet-induced murine model of type 2 diabetes. Microbes and Infection, 22 (8). pp. 303-311.

Sathkumara, Harindra D., Muruganandah, Visai, Cooper, Martha M., Field, Matt A., Alim, Md Abdul, Brosch, Roland, Ketheesan, Natkunam, Govan, Brenda, Rush, Catherine M., Henning, Lars, and Kupz, Andreas (2020) Mucosal delivery of ESX-1–expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes. National Academy of Sciences. Proceedings, 117 (34). pp. 20848-20859.

Kupz, Andreas, Pai, Saparna, Giacomin, Paul R., Whan, Jennifer A., Walker, Robert A., Hammoudi, Pierre-Mehdi, Smith, Nicholas C., and Miller, Catherine M. (2020) Treatment of mice with S4B6 IL‑2 complex prevents lethal toxoplasmosis via IL‑12‑ and IL‑18‑dependent interferon‑gamma production by non‑CD4 immune cells. Scientific Reports, 10. 13115.

Pai, Saparna, Muruganandah, Visai, and Kupz, Andreas (2020) What lies beneath the airway mucosal barrier? Throwing the spotlight on antigen-presenting cell function in the lower respiratory tract. Clinical & Translational Immunology, 9 (e1158).

Ratnatunga, Champa N., Lutzky, Viviana P., Kupz, Andreas, Doolan, Denise L., Reid, David W., Field, Matthew, Bell, Scott C., Thomson, Rachel M., and Miles, John J. (2020) The rise of non-tuberculosis mycobacterial lung disease. Frontiers in Immunology, 11. 303.

Muruganandah, Visai, Sathkumara, Harindra D., Pai, Saparna, Rush, Catherine M., Brosch, Roland, Waardenberg, Ashley J., and Kupz, Andreas (2020) A systematic approach to simultaneously evaluate safety, immunogenicity, and efficacy of novel tuberculosis vaccination strategies. Science Advances, 6 (10).

Sathkumara, Harindra D., Pai, Saparna, de Jesús Aceves-Sánchez, Michel, Ketheesan, Natkunam, Flores-Valdez, Mario Alberto, and Kupz, Andreas (2019) BCG vaccination prevents reactivation of latent lymphatic murine tuberculosis independently of CD4+ T cells. Frontiers in Immunology, 10. 532.

Alim, Md Abdul, Sikder, Suchandan, Sathkumara Mudiyanselage, Harindra, Kupz, Andreas, Rush, Catherine M., Govan, Brenda L., and Ketheesan, Natkunam (2019) Dysregulation of key cytokines may contribute to increased susceptibility of diabetic mice to Mycobacterium bovis BCG infection. Tuberculosis, 115. pp. 113-120.

Chenery, Alistair L., Alhallaf, Rafid, Agha, Zainab, Ajendra, Jesuthas, Parkinson, James E., Cooper, Martha M., Chan, Brian H. K., Eichenberger, Ramon M., Dent, Lindsay A., Robertson, Avril A. B., Kupz, Andreas, Brough, David, Loukas, Alex, Sutherland, Tara E., Allen, Judith E., and Giacomin, Paul R. (2019) Inflammasome-independent role for NLRP3 in controlling innate antihelminth immunity and tissue repair in the lung. Journal of Immunology, 203 (10). 1900640. pp. 2724-2734.

Bachem, Annabell, Makhlouf, Christina, Binger, Katrina J., de Souza, David P., Tull, Deidra, Hochheiser, Katharina, Whitney, Paul G., Fernandez-Ruiz, Daniel, Dähling, Sabrina, Kastenmüller, Wolfgang, Jönsson, Johanna, Gressier, Elise, Lew, Andrew M., Perdomo, Carolina, Kupz, Andreas, Figgett, William, Mackay, Fabienne, Oleshansky, Moshe, Russ, Brendan E., Parish, Ian A., Kallies, Axel, McConville, Malcolm J., Turner, Stephen J., Gebhardt, Thomas, and Bedoui, Sammy (2019) Microbiota-derived short-chain fatty acids promote the memory potential of antigen-activated CD8+ T cells. Immunity, 51. pp. 285-297.

Lutzky, Viviana P., Ratnatunga, Champa N., Smith, Daniel J., Kupz, Andreas, Doolan, Denise, Reid, David W., Thomson, Rachel M., Bell, Scott B., and Miles, John J. (2018) Anomalies in T cell function are associated with individuals at risk of Mycobacterium abscessus complex infection. Frontiers in Immunology, 9. 1319.

Alhallaf, Rafid, Agha, Zainab, Miller, Catherine M., Robertson, Avril A.B., Sotillo-Gallego, Javier, Croese, John, Cooper, Matthew A., Masters, Seth L., Kupz, Andreas, Smith, Nicholas C., Loukas, Alex, and Giacomin, Paul R. (2018) The NLRP3 inflammasome suppresses protective immunity to gastrointestinal helminth infection. Cell Reports, 23 (4). pp. 1085-1098.

Muruganandah, Visai, Sathkumara, Harindra D., Navarro, Severine, and Kupz, Andreas (2018) A systematic review: the role of resident memory T cells in infectious diseases and their relevance for vaccine development. Frontiers in Immunology, 9. 1574. pp. 1-21.

Beigier-Bompadre, Macarena, Montagna, Georgina N., Kuhl, Anja A., Lozza, Laura, Weiner, January, Küpz, Andreas, Vogelzang, Alexis, Mollenkopf, Hans-Joachim, Löwe, Delia, Bandermann, Silke, Dorhoi, Anca, Brinkmann, Volker, Matuschewski, Kai, and Kaufmann, Stefan H.E. (2017) Mycobacterium tuberculosis infection modulates adipose tissue biology. PLoS Pathogens, 13 (10). e1006676.

Perdomo, Carolina, Zedler, Ulrike, Kühl, Anja A., Lozza, Laura, Saikali, Philippe, Sander, Leif E., Vogelzang, Alexis, Kaufmann, Stefan H.E., and Kupz, Andreas (2016) Mucosal BCG vaccination induces protective lung-resident memory T cell populations against tuberculosis. mBio, 7 (6). e01686-16. pp. 1-11.

Bayer-Santos, Ethel, Durkin, Charlotte H., Rigano, Luciano A., Kupz, Andreas, Alix, Eric, Cerny, Ondrej, Jennings, Elliott, Liu, Mei, Ryan, Aindrias S., Lapaque, Nicolas, Kaufmann, Stefan H.E., and Holden, David W. (2016) The Salmonella effector SteD mediates MARCH8-dependent ubiquitination of MHC II molecules and inhibits T cell activation. Cell Host & Microbe, 20 (5). pp. 584-595.

Kupz, Andreas, Zedler, Ulrike, Stäber, Manuela, Perdomo, Carolina, Dorhoi, Anca, Brosch, Roland, and Kaufmann, Stefan H.E. (2016) ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo. Journal of Clinical Investigation, 126 (6). pp. 2109-2122.

Kupz, Andreas, Zedler, Ulrike, Stäber, Manuela, and Kaufmann, Stefan H.E. (2016) A mouse model of latent tuberculosis infection to study intervention strategies to prevent reactivation. PLoS ONE, 11 (7). e0158849. pp. 1-13.

Helmstetter, Caroline, Flossdorf, Michael, Peine, Michael, Kupz, Andreas, Zhu, Jinfang, Hegazy, Ahmed N., Duque-Correa, Maria A., Zhang, Qin, Vainshtein, Yevhen, Radbruch, Andreas, Kaufmann, Stefan H., Paul, William E., Hofer, Thomas, and Lohning, Max (2015) Individual T helper cells have a quantitative cytokine memory. Immunity, 42 (1). pp. 108-122.

Kupz, Andreas, Curtiss III, Roy, Bedoui, Sammy, and Strugnell, Richard A. (2014) In vivo IFN-γ secretion by NK cells in response to Salmonella Typhimurium requires NLRC4 inflammasomes. PLoS ONE, 9 (5). e97418. pp. 1-5.

Strugnell, Richard A., Scott, Timothy A., Wang, Nancy, Yang, Chenying, Peres, Newton, Bedoui, Sammy, and Kupz, Andreas (2014) Salmonella vaccines: lessons from the mouse model or bad teaching? Current Opinion in Microbiology, 17. pp. 99-105.

Kupz, Andreas, Bedoui, Sammy, and Strugnell, Richard A. (2014) Cellular requirements for systemic control of Salmonella enterica serovar Typhimurium infections in mice. Infection and Immunity, 82 (12). pp. 4997-5004.

Heimesaat, Markus M., Kupz, Andreas, Fischer, André, Nies, Dietrich H., Grass, Gregor, Göbel, Ulf B., and Bereswill, Stefan (2013) Colonization resistance against genetically modified Escherichia coli K12 (W3110) strains is abrogated following broad-spectrum antibiotic treatment and acute ileitis. European Journal of Microbiology and Immunology, 3 (3). pp. 222-228.

Kupz, Andreas, Fischer, André, Nies, Dietrich H., Grass, Gregor, Göbel, Ulf B., Bereswill, Stefan, and Heimesaat, Markus M. (2013) Impact of metal ion homeostasis of genetically modified Escherichia coli Nissle 1917 and K12 (W3110) strains on colonization properties in the murine intestinal tract. European Journal of Microbiology and Immunology, 3 (3). pp. 229-235.

Kupz, Andreas, Scott, Timothy A., Belz, Gabrielle T., Andrews, Daniel M., Greyer, Marie, Lew, Andrew M., Brooks, Andrew G., Smyth, Mark J., Curtiss, Roy, Bedoui, Sammy, and Strugnell, Richard A. (2013) Contribution of Thy1+ NK cells to protective IFN-γ production during Salmonella Typhimurium infections. Proceedings of the National Academy of Sciences of the United States of America, 110 (6). pp. 2252-2257.

Hennebry, Sarah C., Sait, Leanne C., Mantena, Raju, Humphery, Thomas J., Yang, Ji, Scott, Timothy, Kupz, Andreas, Richardson, Samantha J., and Strugnell, Richard A. (2012) Salmonella typhimurium's transthyretin-like protein is a host-specific factor important in fecal survival in chickens. PLoS ONE, 7 (12). e46675. pp. 1-11.

Kupz, Andreas, Guarda, Greta, Gebhardt, Thomas, Sander, Leif E., Short, Kirsty R., Diavatopoulos, Dimitri A., Wijburg, Odilia L.C., Cao, Hanwei, Waithman, Jason C., Chen, Weisan, Fernandez-Ruiz, Daniel, Whitney, Paul G., Heath, William R., Curtis, Roy, Tschopp, Jürg, Strugnell, Richard A., and Bedoui, Sammy (2012) NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells. Nature Immunology, 13 (2). pp. 162-169.

Bedoui, Sammy, Kupz, Andreas, Wijburg, Odilia L., Walduck, Anna K., Rescigno, Maria, and Strugnell, Richard A. (2010) Different bacterial pathogens, different strategies, yet the aim is the same: evasion of intestinal dendritic cell recognition. Journal of Immunology, 184 (5). pp. 2237-2242.

Greenhill, A.R., Shipton, W.A., Blaney, B.J., Brock, I.J., Kupz, A., and Warner, J.M. (2009) Spontaneous fermentation of traditional sago starch in Papua New Guinea. Food Microbiology, 26 (2). pp. 136-141.

Heimesaat, Markus M., Fischer, André, Siegmund, Britta, Kupz, Andreas, Niebergall, Julia, Fuchs, David, Jahn, Hannah-Katharina, Freudenberg, Marina, Loddenkemper, Christoph, Batra, Arvind, Lehr, Hans-Anton, Liesenfeld, Oliver, Blaut, Michael, Göbel, Ulf B., Schumann, Ralf R., and Bereswill, Stefan (2007) Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via toll-like receptors 2 and 4. PLoS ONE, 2 (7). e662. pp. 1-7.