Sable, Suraj B., Velu, Vijayakumar, and Kupz, Andreas (2026) Editorial: Vaccines and molecular therapeutics for tuberculosis. Frontiers in Immunology, 17. 1809428.

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Abstract

[Extract] Tuberculosis (TB) vaccinology is at a critical juncture. While Bacille Calmette–Guérin (BCG) has been used as a vaccine for a century and offers strong protection against severe disseminated disease in infants, its effectiveness against adult pulmonary TB varies significantly. Currently, a growing pipeline of vaccines, including protein-adjuvant boosters, acellular mycobacterial products, nanoparticle- and nucleic acid platforms, has demonstrated robust immune responses, though the precise correlates of protection and indicators of immunity remain unclear. The collection of articles published in the Research Topic “Vaccines and Molecular Therapeutics for Tuberculosis” indicates that the field isn’t lacking new vaccine ideas; rather, it is still exploring how to induce protective immunity within lung microenvironments where Mycobacterium tuberculosis (Mtb) persists. T

Item ID:	91314
Item Type:	Article (Editorial)
ISSN:	1664-3224
Copyright Information:	© 2026 Sable, Velu and Kupz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Date Deposited:	29 Apr 2026 02:48
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320402 Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies) @ 100%
SEO Codes:	28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280103 Expanding knowledge in the biomedical and clinical sciences @ 100%
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