Publications by: Mark S. Pearson

Also publishes as (M.S. Pearson, M. Pearson, Mark Pearson)

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Number of items: 40.

Wangchuk, Phurpa, Pearson, Mark S., Giacomin, Paul R., Becker, Luke, Sotillo, Javier, Pickering, Darren, Smout, Michael J., and Loukas, Alex (2016) Compounds derived from the Bhutanese daisy, Ajania nubigena, demonstrate dual anthelmintic activity against Schistosoma mansoni and Trichuris muris. PLOS Neglected Tropical Diseases, 10 (8). pp. 1-18.

Susilawati, T.N., Jex, A.R., Cantacessi, C., Pearson, M., Navarro, S., Susianto, A., Loukas, A.C., and McBride, W.J.H. (2016) Deep sequencing approach for investigating infectious agents causing fever. European Journal of Clinical Microbiology and Infectious Diseases, 35 (7). pp. 1137-1149.

Driguez, Patrick, Li, Yuesheng, Gaze, Soraya, Pearson, Mark S., Nakajima, Rie, Trieu, Angela, Doolan, Denise L., Felgner, Philip L., Hou, Xunya, Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey, Loukas, Alex, and McManus, Donald (2016) Antibody signatures reflect different disease pathologies in patients with schistosomiasis due to Schistosoma japonicum. Journal of Infectious Diseases, 213 (1). pp. 122-130.

Sotillo, Javier, Pearson, Mark, Potriquet, Jeremy, Becker, Luke, Pickering, Darren, Mulvenna, Jason, and Loukas, Alex (2016) Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates. International Journal for Parasitology, 46 (1). pp. 1-5.

Wangchuk, Phurpa, Giacomin, Paul R., Pearson, Mark S., Smout, Michael J., and Loukas, Alex (2016) Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms. Scientific Reports, 6. pp. 1-10.

Driguez, Patrick, McWilliam, Hamish E.G., Gaze, Soraya, Piedrafita, David, Pearson, Mark S., Nakajima, Rie, Duke, Mary, Trieu, Angela, Doolan, Denise L., Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey N., Felgner, Philip L., Loukas, Alex, Meeusen, Els, and McManus, Donald P. (2016) Specific humoral response of hosts with variable schistosomiasis susceptibility. Immunology and Cell Biology, 94. pp. 52-65.

Sotillo, Javier, Pearson, Mark, Becker, Luke, Mulvenna, Jason, and Loukas, Alex (2015) A quantitative proteomic analysis of the tegumental proteins from Schistosoma mansoni schistosomula reveals novel potential therapeutic targets. International Journal for Parasitology, 45 (8). pp. 505-516.

Pearson, Mark S., Becker, Luke, Driguez, Patrick, Young, Neil D., Gaze Jangola, Soraya, Mendes, Tiago, Li, Xiao-Hong, Doolan, Denise L., Midzi, Nicholas, Mduluza, Takafira, McManus, Donald P., Wilson, R. Alan, Bethony, Jeffrey M., Nausch, Norman, Mutapi, Francisca, Felgner, Philip L., and Loukas, Alex (2015) Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Frontiers in Immunology, 6. pp. 1-13.

Pearson, Mark S., Jariwala, Amar R., Abbenante, Giovanni, Plieskatt, Jordan, Wilson, David, Bottazzi, Maria Elena, Hotez, Peter J., Keegan, Brian, Bethony, Jeffrey M., and Loukas, Alex (2015) New tools for NTD vaccines: a case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Human Vaccines & Immunotherapeutics, 11 (5). pp. 1251-1257.

Fuaad, Abdullah A.H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzho, Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan, and UNSPECIFIED (2015) Lipopeptide nanoparticles: development of vaccines against hookworm parasite. ChemMedChem, 10 (10). pp. 1647-1654.

Ahmad Fuaad, Abdullah A.H., Roubille, Romain, Pearson, Mark S., Pickering, Darren A., Loukas, Alex C., Skwarczynski, Mariusz, and Toth, Istvan (2015) The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni. Bioorganic & Medicinal Chemistry, 23. pp. 1307-1312.

Gaze, Soraya, Driguez, Patrick, Pearson, Mark S., Mendes, Tiago, Doolan, Denise L., Trieu, Angela, McManus, Donald P., Gobert, Geoffrey N., Periago, Maria Victoria, Correa Oliveira, Rodrigo, Cardoso, Fernanda C., Oliveira, Guilherme, Nakajima, Rie, Jasinskas, Al, Hung, Chris, Liang, Li, Pablo, Jozelyn, Bethony, Jeffrey M., Felgner, Philip L., and Loukas, Alex (2014) An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathogens, 10 (3). pp. 1-16.

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J., and Mulvenna, Jason (2014) Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10). pp. 7151-7163.

Kline, Kevin, McCarthy, James S., Pearson, Mark, Loukas, Alex, and Hotez, Peter J. (2013) Neglected tropical diseases of oceania: review of their prevalence, distribution, and opportunities for control. PLoS Neglected Tropical Disease, 7 (1). pp. 1-9.

Pearson, Mark S., Pickering, Darren, Ranjit, Najju, and Loukas, Alex (2013) Hookworm MEP-1 metalloproteases. In: Rawlings, Neil D., and Salvesen, Guy, (eds.) Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes, 1 . Elsevier, Amsterdam, The Netherlands, pp. 647-649.

Dougall, Annette M., Pearson, Mark S., and Loukas, Alex (2013) Na-APR-1 (aka necepsin-2). In: Rawlings, Neil D., and Salvesen, Guy, (eds.) Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes, 1 . Elsevier, Amsterdam, The Netherlands, pp. 113-118.

Pearson, Mark S., Tribolet, Leon, Cantacessi, Cinzia, Periago, Maria Victoria, Adela Valerio, Maria, Jariwala, Amar R., Hotez, Peter, Diemert, David, Loukas, Alex, and Bethony, Jeffrey (2012) Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. Journal of Allergy and Clinical Immunology, 130 (1). pp. 13-21.

Loukas, A., Ranjit, N., Pickering, D.A., and Pearson, M.S. (2012) Blood-feeding human hookworm proteases. In: Dunn, Ben, (ed.) Proteinases as Drug Targets. Royal Society of Chemistry, Cambridge, UK, pp. 186-198.

Pearson, Mark S., Pickering, Darren A., McSorley, Henry J., Bethony, Jeffrey M., Tribolet, Leon, Dougall, Annette M., Hotez, Peter J., and Loukas, Alex (2012) Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Neglected Tropical Diseases, 6 (3). pp. 1-10.

Skwarczynski, Mariusz, Dougall, Annette M., Khoshnejad, Makan, Chandrudu, Saranya, Pearson, Mark, Loukas, Alex, and Toth, Istvan (2012) Peptide-based subunit vaccine against hookworm infection. PLoS One, 7 (10). pp. 1-7.

Loukas, Alex, Gaze, Soraya, Pearson, Mark, Doolan, Denise, Felgner, Philip, Diemert, David, McManus, Donald P., Driguez, Patrick, and Bethony, Jeffrey (2012) Schistosomiasis vaccines: new approaches to antigen discovery and promising new candidates. In: Caffrey, Conor R., (ed.) Parasitic Helminths: targets, screens, drugs and vaccines. Drug Discovery in Infectious Diseases . Wiley-Blackwell, Weinheim, Germany, pp. 421-433.

Hewitson, James P., Filbey, Kara J., Grainger, John R., Dowle, Adam A., Pearson, Mark, Murray, Janice, Harcus, Yvonne, and Maizels, Rick M. (2011) Heligmosomoides polygyrus elicits a dominant, non-protective antibody response directed against restricted glycan and peptide epitopes. Journal of Immunology, 187 (9). pp. 4764-4777.

Hotez, Peter J., Bethony, Jeffrey M., Diemert, David J., Pearson, Mark, and Loukas, Alex (2010) Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews Microbiology , 8 (11). pp. 814-826.

Amante, Fiona H., Haque, Ashraful, Stanley, Amanda C., de Labastida Rivera, Fabian, Randall, Louise M., Wilson, Yana A., Yeo , Gladys, Pieper, Christian, Crabb, Brendan S., de Koning-Ward, Tania F., Lundie, Rachel J., Good, Michael F., Pinzon-Charry, Alberto, Pearson, Mark S., Duke, Mary G., McManus, Donald P., Loukas, Alex, Hill, Geoff R., and Engwerda, Christian R. (2010) Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. Journal of Immunology, 185 (6). pp. 3632-3642.

Pearson, Mark S., Ranjit, Najju, and Loukas, Alex (2010) Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasites. Biological Chemistry, 391 (8). pp. 901-911.

Pearson, Mark S., Pickering, Darren A., Tribolet, Leon, Cooper, Leanne, Mulvenna, Jason, Oliveira, Luciana M., Bethony, Jeffrey M., Hotez, Peter J., and Loukas, Alex (2010) Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm Infection and schistosomiasis. Journal of Infectious Diseases, 201 (10). pp. 1561-1569.

Ruyssers, Nathalie E., De Winter, Benedicte Y., De Man, Joris G., Ruyssers, Natacha D., Van Gils, Ann J., Loukas, Alex, Pearson, Mark S., Weinstock, Joel V., Pelckmans, Paul A., and Moreels, Tom G. (2010) Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice. World Journal of Gastroenterology, 16 (6). pp. 703-712.

Pearson, Mark S., Bethony, Jeffrey M., Pickering, Darren A., de Oliveira, Luciana M., Jariwala, Amar, Santiago, Helton, Miles, Aaron P., Zhan, Bin, Jiang, Desheng, Ranjit, Najju, Mulvenna, Jason, Tribolet, Leon, Plieskatt, Jordan, Smith, Tracey, Bottazzi, Maria Elena, Jones, Kathryn, Keegan, Brian, Hotez, Peter J., and Loukas, Alex (2009) An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB Journal, 23 (9). pp. 3009-3017.

Ruyssers, Nathalie E., De Winter, Benedicte Y., De Man, Joris G., Loukas, Alex, Pearson, Mark, Weinstock, Joel V., Van den Bossche, Rita M., Martinet, Wim, Pelckmans, Paul A., and Moreels, Tom G. (2009) Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice. Inflammatory Bowel Diseases, 15 (4). pp. 491-500.

Ranjit, Najju, Zhan, Bin, Hamilton, Brett, Stenzel, Deborah, Lowther, Jonathan, Pearson, Mark, Gorman, Jeffrey, Hotez, Peter, and Loukas, Alex (2009) Proteolytic degradation of hemoglobin in the intestine of the human hookworm necator Americanus. Journal of Infectious Diseases, 199 (6). pp. 904-912.

Suttiprapa, Sutas, Mulvenna, Jason, Huong, Ngo Thi, Pearson, Mark S., Brindley, Paul J., Laha, Thewarach, Wongkham, Sopit, Sripa, Banchob, and Loukas, Alex (2009) Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: functional expression, immunolocalization and subsite specificity. International Journal of Biochemistry & Cell Biology, 41 (5). pp. 1148-1156.

Laha, Thewarach, Sripa, Jittiyawadee, Sripa, Banchob, Pearson, Mark, Tribolet, Leon, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Brindley, Paul J., and Loukas, Alex (2008) Asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and its potential for serodiagnosis. International journal of infectious diseases, 12 (6). e49-e59.

Pearson, M.S, McManus, D.P., Smyth, D.J., Jones, M.K., Sykes, A.M., and Loukas, A. (2007) Cloning and characterization of an orphan seven transmembrane receptor from Schistosoma mansoni. Parasitology, 134 (14). pp. 2001-2008.

Loukas, Alex, Tran, Mai, and Pearson, Mark S. (2007) Schistosome membrane proteins as vaccines. International Journal for Parasitology, 37 (3-4). pp. 257-263.

Tran, Mai H., Pearson, Mark S., Bethony, Jeffrey M., Smyth, Danielle J., Jones, Malcolm K., Duke, Mary, Don, Tegan A., McManus, Donald P., Correa-Oliveira, Rodrigo, and Loukas, Alex (2006) Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nature Medicine, 12 (7). pp. 835-840.

Rosenzvit, Mara C., Zhang, Wenbao, Motazedian, Hossein, Smyth, Danielle, Pearson, Mark, Loukas, Alex, Jones, Malcolm K., and McManus, Donald P. (2006) Identification of membrane-bound and secreted proteins from Echinococcus granulosus by signal sequence trap. International Journal for Parasitology, 36 (1). pp. 123-130.

Pearson, Mark S., McManus, Donald P., Smyth, Danielle J., Lewis, Fred A., and Loukas, Alex (2005) In vitro and in silico analysis of signal peptides from the human blood fluke, Schistosoma mansoni. FEMS Immunology and Medical Microbiology, 45 (2). pp. 201-11.

Le, T.H., Pearson, M.S., Blair, D., Dai, N., Zhang, L.H., and McManus, D.P. (2002) Complete mitochondrial genomes confirm the distinctiveness of the horse-dog and sheep-dog strains of Echinococcus granulosus. Parasitology, 124 (1). pp. 97-112.

Pearson, Mark, Le, Thanh Hoa, Zhang, Li Hua, Blair, David, Dai, Thi Hang Nga, and McManus, Donald Peter (2002) Molecular taxonomy and strain analysis in Echinococcus. In: Craig, Philip, and Pawlowski, Zbigniew, (eds.) Cestode Zoonoses: echinococcosis and cysticercosis: an emergent and global problem. NATO Science Series I: life and behavioural sciences, 341 . IOS Press, Posnan, Poland, pp. 205-219.

McManus, Donald P., Zhang, Lihua, Castrodale, Louisa J., Le, Thanh Hoa, Pearson, Mark, and Blair, David (2002) Short report: molecular genetic characterization of an unusually severe case of hydatid disease in Alaska caused by the cervid strain of Echinococcus granulosus. American Journal of Tropical Medicine & Hygiene, 67 (3). pp. 296-298.

This list was generated on Sun Oct 22 18:06:57 2017 AEST.