Peck, Yoshimi, Pickering, Darren, Mobli, Mehdi, Liddell, Michael J., Wilson, David T, Ruscher, Roland, Ryan, Stephanie, Buitrago, Geraldine, McHugh, Connor, Love, Nicholas C., Pinlac, Theresa, Haertlein, Michael, Kron, Michael A., Loukas, Alex, and Daly, Norelle L. (2024) Solution structure of the N-terminal extension domain of a Schistosoma japonicum asparaginyl-tRNA synthetase. Journal of Biomolecular Structure and Dynamics. (In Press)

Takjoo, Rozita, Wilson, David T., Bansal, Paramjit S., Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2023) Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1. Exploration of Drug Science, 1. pp. 172-179.

Giribaldi, Julien, Chemin, Jean, Tuifua, Marie, Deuis, Jennifer R., Mary, Rosanna, Vetter, Irina, Wilson, David T, Daly, Norelle L., Schroeder, Christina I., Bourinet, Emmanuel, and Dutertre, Sébastien (2023) Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV1.7 and hCaV3 voltage-gated channels. FEBS Journal, 290 (14). pp. 3688-3702.

Dongol, Yashad, Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C., and Lewis, Richard J. (2023) Structure-function and rational design of a spider toxin Ssp1a at human voltage-gated sodium channel subtypes. Frontiers in Pharmacology, 14. 1277143.

Ritmejeryte, Edita, Ryan, Rachael Y.M., Byatt, Brendan J., Peck, Yoshimi, Yeshi, Karma, Daly, Norelle L., Zhao, Guangzu, Crayn, Darren, Loukas, Alex, Pyne, Stephen G., Ruscher, Roland, and Wangchuk, Phurpa (2022) Anti-inflammatory properties of novel galloyl glucosides isolated from the Australian tropical plant Uromyrtus metrosideros. Chemico-Biological Interactions, 368. 110124.

Faraji, Naser, Arab, Seyed Shahriar, Doustmohammadi, Alireza, Daly, Norelle L., and Khosroushahi, Ahmad Yari (2022) ApInAPDB: a database of apoptosis-inducing anticancer peptides. Scientific Reports, 12. 21341.

Schmidt, Casey A., Cooke, Ira, Wilson, David T., Miller, David J., Peigneur, Steve, Tytgat, Jan, Field, Matthew, Takjoo, Rozita, Smout, Michael J., Loukas, Alex, and Daly, Norelle L. (2022) Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity. Journal of Natural Products, 85 (7). pp. 1789-1798.

Cobos, Claudia, Bansal, Paramjit S., Wilson, David T., Jones, Linda, Zhao, Guangzu, Field, Matthew A., Eichenberger, Ramon M., Pickering, Darren A., Ryan, Rachael Y.M., Ratnatunga, Champa N., Miles, John J., Ruscher, Roland, Giacomin, Paul R., Navarro, Severine, Loukas, Alex, and Daly, Norelle L. (2022) Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells. Frontiers in Medicine, 9. 934852.

Malik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L., and Craik, David J. (2021) Development of novel frog-skin peptide scaffolds with selectivity towards melanocortin receptor subtypes. Peptide Science, 113 (4). e24209.

Khudhair, Zainab, Alhallaf, Rafid, Eichenberger, Ramon M., Whan, Jen, Kupz, Andreas, Field, Matt, Krause, Lutz, Wilson, David T., Daly, Norelle L., Giacomin, Paul, Sotillo, Javier, and Loukas, Alex (2021) Gastrointestinal helminth infection improves insulin sensitivity, decreases systemic inflammation, and alters the composition of gut microbiota in distinct mouse models of Type 2 diabetes. Frontiers in Endocrinology, 11. 606530.

Sharp, Michael F., Taki, Aya C., Ruethers, Thimo, Stephen, Juan N., Daly, Norelle L., Lopata, Andreas L., and Kamath, Sandip D. (2021) IgE and IgG4 epitopes revealed on the major fish allergen Lat c 1. Molecular Immunology, 131. pp. 155-163.

Daly, Norelle L., and Wilson, David T. (2021) Plant derived cyclic peptides. Biochemical Society Transactions, 49 (3). pp. 1279-1285.

Giribaldi, Julien, Haufe, Yves, Evans, Edward R.J., Wilson, David T., Daly, Norelle L., Enjalbal, Christine, Nicke, Annette, and Dutertre, Sébastien (2021) Synthesis, structural and pharmacological characterizations of CIC, a novel α-conotoxin with an extended n-terminal tail. Marine Drugs, 19 (3). 141.

Dongol, Yashad, Choi, Phil M., Wilson, David T., Daly, Norelle L., Cardoso, Fernanda C., and Lewis, Richard J. (2021) Voltage-Gated Sodium Channel Modulation by a New Spider Toxin Ssp1a Isolated From an Australian Theraphosid. Frontiers in Pharmacology, 12. 795455.

Buitrago, Geraldine, Pickering, Darren, Ruscher, Roland, Cobos Caceres, Claudia, Jones, Linda, Cooper, Martha, Van Waardenberg, Ashley, Ryan, Stephanie, Miles, Kim, Field, Matthew, Dredge, Keith, Daly, Norelle L., Giacomin, Paul R., and Loukas, Alex (2021) A netrin domain-containing protein secreted by the human hookworm Necator americanus protects against CD4 T cell transfer colitis. Translational Research, 232. pp. 88-102.

Giribaldi, Julien, Haufe, Yves, Evans, Evans R.J., Amar, Muriel, Durner, Anna, Schmidt, Casey, Faucherre, Adèle, Moha Ou Maati, Hamid, Enjalbal, Christine, Molgó, Jordi, Servent, Denis, Wilson, David T., Daly, Norelle L., and Nicke, Annette (2020) Backbone cyclization turns a venom peptide into a stable and equipotent ligand at both muscle and neuronal nicotinic receptors. Journal of Medicinal Chemistry, 63 (21). pp. 12682-12692.

Wilson, David, Bansal, Paramjit S., Carter, David A., Vetter, Irina, Nicke, Annette, Dutertre, Sébastien, and Daly, Norelle (2020) Characterisation of a novel A-superfamily conotoxin. Biomedicines, 8 (5). 128.

Takjoo, Rozita, Wilson, David T., Bansal, Paramjit, Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2020) Folding of truncated granulin peptides. Biomolecules, 10 (8). 1152.

Schmidt, Casey A., Wilson, David T., Cooke, Ira, Potriquet, Jeremy, Tungatt, Katie, Muruganandah, Visai, Boote, Chloe, Kuek, Felicity, Miles, John J., Kupz, Andreas, Ryan, Stephanie, Loukas, Alex, Bansal, Paramjit S., Takjoo, Rozita, Miller, David J., Peigneur, Steve, Tytgat, Jan, and Daly, Norelle (2020) Identification and characterization of a peptide from the stony coral Heliofungia actiniformis. Journal of Natural Products, 83 (11). pp. 3454-3463.

Ng, Susanna S., Rivera, Fabian De Labastida, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C.M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., de Oca, Marcela Montes, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona, Edwards, Chelsea L., Haque, Ashraful, Dougall, William C., Singh, Om Prakash, Baxter, Alan G., Teng, Michele W.L., Loukas, Alex, Daly, Norelle L., Cloonan, Nicole, Degli-esposti, Mariapia, Uzonna, Jude, Heath, William R., Bald, Tobias, Tey, Siok-Keen, Nakamura, Kyohei, Hill, Geoffrey R., Kumar, Rajiv, Sundar, Shyam, Smyth, Mark J, and Engwerda, Christian R. (2020) The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology, 21. pp. 1205-1217.

Yeshi, Karma, Ruscher, Roland, Hunter, Luke, Daly, Norelle, Loukas, Alex, and Wangchuk, Phurpa (2020) Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products. Journal of Clinical Medicine, 9 (5). 1273.

Evans, Edward R.J., McIntyre, Lachlan, Northfield, Tobin, Daly, Norelle L., and Wilson, David T. (2020) Small molecules in the venom of the scorpion Hormurus waigiensis. Biomedicines, 8 (8). 259.

Giribaldi, Julien, Ragnarsson, Lotten, Pujante, Tom, Enjalbal, Christine, Wilson, David, Daly, Norelle L., Lewis, Richard J., and Dutertre, Sebastien (2020) Synthesis, pharmacological and structural characterization of novel conopressins from Conus miliaris. Marine Drugs, 18 (3). 150.

Fingerhut, Legana C. H. W., Miller, David J., Strugnell, Jan M., Daly, Norelle L., and Cooke, Ira R. (2020) ampir: an R package for fast genome-wide prediction of antimicrobial peptides. Bioinformatics, 36 (21). btaa653.

Dastpeyman, Mohadeseh, Giacomin, Paul, Wilson, David, Nolan, Matthew J., Bansal, Paramjit S., and Daly, Norelle L. (2019) A C-terminal fragment of chlorotoxin retains bioactivity and inhibits cell migration. Frontiers in Pharmacology, 10. 250.

Schmidt, Casey A., Daly, Norelle L., and Wilson, David T. (2019) Coral venom toxins. Frontiers in Ecology and Evolution, 7. 320.

Hu, Mingjing, Eviston, David, Hsu, Peter, Mariño, Eliana, Chidgey, Ann, Santner-Nanan, Brigitte, Wong, Kahlia, Richards, James L., Yap, Yu Anne, Collier, Fiona, Quinton, Ann, Joung, Steven, Peek, Michael, Benzie, Ron, Macia, Laurence, Wilson, David, Ponsonby, Ann-Louise, Tang, Mimi L. K., O'Hely, Martin, Daly, Norelle L., Mackay, Charles R., Dahlstrom, Jane E., The BIS Investigator Group, Vuillermin, Peter, and Nanan, Ralph (2019) Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia. Nature Communications, 10. 3031.

Wangchuk, Phurpa, Shepherd, Catherine, Constantinoiu, Constantin, Ryan, Rachael Y.M., Kouremenos, Konstantinos A., Becker, Luke, Jones, Linda, Buitrago, Geraldine, Giacomin, Paul, Wilson, David, Daly, Norelle, Mcconville, Malcolm J., Miles, John J., and Loukas, Alex (2019) Hookworm-derived metabolites suppress pathology in a mouse model of colitis and inhibit secretion of key inflammatory cytokines in primary human leukocytes. Infection and Immunity, 87 (4). e00851-18.

Evans, Edward R.J., Northfield, Tobin D., Daly, Norelle L., and Wilson, David T. (2019) Venom costs and optimization in scorpions. Frontiers in Ecology and Evolution, 7. 196.

Wilson, David, and Daly, Norelle L. (2018) Approaches to delineate disulfide connectivities in pharmaceutical peptides. In: Webb, Graham A., (ed.) Modern Magnetic Resonance. Springer International Publishing, Gewerbestrasse, Cham, Switzerland, pp. 2021-2034.

Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Fuaad, Abdullah Ahmad, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T., and Craik, David J. (2018) Development of novel melanocortin receptor agonists based on the cyclic peptide framework of sunflower trypsin inhibitor-1. Journal of Medicinal Chemistry, 61 (8). pp. 3674-3684.

Cobos, Claudia, Bansal, Paramjit S., Jones, Linda, Wangchuk, Phurpa, Wilson, David, Loukas, Alex, and Daly, Norelle L. (2018) Engineering of an anti-inflammatory peptide based on the disulfide-rich linaclotide scaffold. Biomedicines, 6 (4). 97.

Dastpeyman, Mohadeseh, Smout, Michael J., Wilson, David, Loukas, Alex, and Daly, Norelle L. (2018) Folding of granulin domains. Peptide Science, 110 (3). e24062.

Wilson, David, and Daly, Norelle L. (2018) Nuclear magnetic resonance seq (NMRseq): a new approach to peptide sequence tags. Toxins, 10 (11). 437. pp. 1-10.

Andreosso, Athena, Bansal, Paramjit S., Smout, Michael J., Wilson, David, Seymour, Jamie E., and Daly, Norelle L. (2018) Structural characterisation of predicted helical regions in the Chironex fleckeri CfTX-1 toxin. Marine Drugs, 16 (6). 201. pp. 1-12.

Daly, Norelle L., and Wilson, David (2018) Structural diversity of arthropod venom toxins. Toxicon, 152. pp. 46-56.

Dastpeyman, Mohadeseh, Bansal, Paramjit S., Wilson, David, Sotillo, Javier, Brindley, Paul J., Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2018) Structural variants of a liver fluke derived granulin peptide potently stimulate wound healing. Journal of Medicinal Chemistry, 61 (19). pp. 8746-8753.

Zhang, Hang, Nielsen, Alexander L., Boesgaard, Michael W., Harpsøe, Kasper, Daly, Norelle L., Xiong, Xiao-Feng, Underwood, Christina R., Haugaard-Kedström, Linda M., Bräuner-Osborne, Hans, Gloriam, David E., and Strømgaard, Kristian (2018) Structure-activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359. European Journal of Medicinal Chemistry, 156. pp. 847-860.

Giribaldi, Julien, Wilson, David, Nicke, Annette, El Hamdaoui, Yamina, Laconde, Guillaume, Faucherre, Adèle, Maati, Hamid Moha Ou, Daly, Norelle L., Enjalbal, Christine, and Dutertre, Sébastien (2018) Synthesis, structure and biological activity of CIA and CIB, two α-conotoxins from the predation-evoked venom of Conus catus. Toxins, 10 (6). 222. pp. 1-12.

Jin, Ai-Hua, Dekan, Zoltan, Smout, Michale J., Wilson, David, Dutertre, Sebastien, Vetter, Irina, Lewis, Richard J., Loukas, Alex, Daly, Norelle L., and Alewood, Paul F. (2017) Conotoxin Phi-MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie International Edition, 56 (47). pp. 14973-14976.

Bansal, Paramjit S., Smout, Michael J., Wilson, David, Cobos Caceres, Claudia, Dastpeyman, Mohadeseh, Sotillo, Javier, Seifert, Julia, Brindley, Paul J., Loukas, Alex, and Daly, Norelle L. (2017) Development of a potent wound healing agent based on the liver fluke granulin structural fold. Journal of Medicinal Chemistry, 60 (10). pp. 4258-4266.

Omaga, Carla, Carpio, Louie D., Imperial, Julita S., Daly, Norelle L., Gajewiak, Joanna, Flores, Malem S., Espino, Samuel S., Christensen, Sean, Filchakova, Olena M., López-Vera, Estuardo, Raghuraman, Shrinivasan, Olivera, Baldomero M., and Concepcion, Gisela P. (2017) Structure and biological activity of a turripeptide from Unedogemmula bisaya venom. Biochemistry, 56 (45). pp. 6051-6060.

Wilson, David, Boyle, Glen M., McIntyre, Lachlan, Nolan, Matthew J., Parsons, Peter G., Smith, Jennifer J., Tribolet, Leon, Loukas, Alex, Liddell, Michael J., Rash, Lachlan D., and Daly, Norelle L. (2017) The aromatic head group of spider toxin polyamines influences toxicity to cancer cells. Toxins, 9 (11). 9110346. pp. 1-13.

Cobos Caceres, Claudia, Bansal, Paramjit S., Navarro, Severine, Wilson, David, Don, Laurianne, Giacomin, Paul, Loukas, Alex, and Daly, Norelle L. (2017) An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease. Journal of Biological Chemistry, 292 (24). pp. 10288-10294.

Zhang, Yi, Schulten, Klaus, Gruebele, Martin, Bansal, Paramjit S., Wilson, David T., and Daly, Norelle L. (2016) Disulfide bridges: bringing together frustrated structure in a bioactive peptide. Biophysical Journal, 110 (8). pp. 1744-1752.

Chan, Lai Yue, Craik, David J., and Daly, Norelle L. (2016) Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy. Scientific Reports, 6. 35347. pp. 1-13.

Daly, Norelle L., Gunasekera, Sunithi, Clark, Richard J., Lin, Feng, Wade, John D., Anderson, Marilyn A., and Craik, David J. (2016) The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured. Biopolymers, 106 (6). pp. 825-833.

Harris, Karen S., Durek, Thomas, Kaas, Quentin, Poth, Aaron G., Gilding, Edward K., Conlan, Brendon F., Saska, Ivana, Daly, Norelle, Van Der Weerden, Nicole L., Craik, David J., and Anderson, Marilyn A, (2015) Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase. Nature Communications, 6. 10199.

Smout, Michael J., Sotillo, Javier, Laha, Thewarach, Papatpremsiri, Atiroch, Rinaldi, Gabriel, Pimenta, Rafael N., Chan, Lai Yue, Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Giacomin, Paul R., Moran, Corey S., Golledge, Jonathan, Daly, Norelle, Sripa, Banchob, Mulvenna, Jason P., Brindley, Paul J., and Loukas, Alex (2015) Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia. PLoS Pathogens, 11 (10). e100520. pp. 1-20.

Huang, Yen-hua, Henriques, Sónia T., Wang, Conan K., Thorstholm, Louise, Daly, Norelle L., Kaas, Quentin, and Craik, David J. (2015) Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Scientific Reports, 5. 12974.

Shepherd, C., Navarro, S., Wangchuk, P., Wilson, D., Daly, N.L., and Loukas, A. (2015) Identifying the immunomodulatory components of helminths. Parasite Immunology, 37 (6). pp. 293-303.

Reeks, Timothy, Jones, Alun, Brust, Andreas, Sridharan, Sindhuja, Corcilius, Leo, Wilkinson, Brendan L., Thaysen-Andersen, Morten, Payne, Richard J., Kini, R. Manjunatha, Daly, Norelle L., and Alewood, Paul F. (2015) A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus. Angewandte Chemie International Edition, 54 (16). pp. 4828-4831.

Malik, U., Silva, O.N, Fensterseifer, I.C.M., Chan, L.Y., Clark, R.J., Franco, O. L. , Daly, N.L., and Craik, D.J. (2015) In vivo efficacy of anuran trypsin inhibitory peptides against Staphylococcal skin infection and the impact of peptide cyclization. Antimicrobial Agents and Chemotherapy, 59 (4). pp. 2113-2121.

Mueller, Alexander, Starobova, Hana, Inserra, Marco C., Jin, Ai-Hua, Deuis, Jennifer R., Dutertre, Sébastien, Lewis, Richard J., Alewood, Paul F., Daly, Norelle L., and Vetter, Irina (2015) α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology, 94 (2). pp. 155-163.

Chan, Lai Yue, Craik, David J., and Daly, Norelle L. (2015) Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration. Bioscience Reports, 35. e00270. pp. 1-12.

Haugaard-Kedström, Linda M. , Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A.D., Rinderknecht, Ernst , Wade, John D., Craik, David J., and Rosengren, K. Johan (2015) Solution structure, aggregation behavior, and flexibility of human relaxin‑2. ACS Chemical Biology, 10 (3). pp. 891-900.

Daly, Norelle L., and Rosengren, K. Johan (2015) Structural studies of cyclotides. Advances in Botanical Research, 76. pp. 155-186.

Akcan, Muharrem, Clark, Richard J., Daly, Norelle L., Conibear, Anne C., de Faoite, Andrew, Heghinian, Mari D., Sahil, Talwar, Adams, David J., Marí, Frank, and Craik, David J. (2015) Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins. Biopolymers, 104 (6). pp. 682-692.

Vink, Simone, Daly, Norelle, Steen, Natalie, Craik, David J., and Alewood, Paul F. (2014) Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90. pp. 308-317.

Berecki, G., Daly, N.L., Huang, Y.H., Vink, S., Craik, D.J., Alewood, P.F., and Adams, D.J. (2014) Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. British Journal of Pharmacology, 171 (13). pp. 3313-3327.

Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric, and Nitabach, Michael N. (2014) A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Current Biology, 24 (5). pp. 473-483.

Schroeder, Christina I., Swedberg, Joakim E., Withka, Jane M., Rosengren, K. Johan, Akcan, Muharrem, Clayton, Daniel J., Daly, Norelle L., Cheneval, Olivier, Borzilleri, Kris A., Griffor, Matt, Stock, Ingrid, Colless, Barbara, Walsh, Phillip, Sunderland, Philip, Reyes, Allan, Dullea, Robert, Ammirati, Mark, Liu, Shenping, McClure, Kim F., Tu, Meihua, Bhattacharya, Samit K., Liras, Spiros, Price, David A., and Craik, David J. (2014) Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chemistry & Biology, 21 (2). pp. 284-294.

Lay, Fung T., Poon, Simon, McKenna, James A., Connelly, Angela A., Barbeta, Barbara L., McGinness, Bruce S., Fox, Jennifer L., Daly, Norelle, Craik, David J., Heath, Robyn L., and Anderson, Marilyn A. (2014) The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions. BMC Plant Biology, 14. 41. pp. 1-13.

Daly, Norelle L., Seymour, Jamie, and Wilson, David (2014) Exploring the therapeutic potential of jellyfish venom. Future Medicinal Chemistry, 6 (15). pp. 1715-1724.

Dougall, Annette M., Skwarczynski, Mariusz, Khoshnejad, Makan, Chandrudu, Saranya, Daly, Norelle L., Toth, Istvan, and Loukas, Alex (2014) Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine. Human Vaccines & Immunotherapeutics, 10 (2). pp. 399-409.

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J., and Mulvenna, Jason (2014) Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10). pp. 7151-7163.

Koehbach, Johannes, O'Brien, Margaret, Muttenthaler, Markus, Miazzo, Marion, Akcan, Muharrem, Elliott, Alysha G., Daly, Norelle L., Harvey, Peta J., Arrowsmith, Sarah, Gunasekera, Sunithi, Smith, Terry J., Wray, Susan, Göransson, Ulf, Dawson, Philip E., Craik, David J., Freissmuth, Michael, and Gruber, Christian W. (2013) Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proceedings of the National Academy of Sciences of the United States of America, 110 (52). pp. 21183-21188.

Daly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begoña, Martin, Jennifer L., and Craik, David J. (2013) Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50). pp. 36141-36148.

He, Wen-Jun, Chan, Lai Yue, Clark, Richard J., Tang, Jun, Zeng, Guang-Zhi, Franco, Octavio L., Cantacessi, Cinzia, Craik, David J., Daly, Norelle L., and Tan, Ning-Hua (2013) Novel inhibitor cystine knot peptides from Momordica charantia. PLoS ONE, 8 (10). e75334. pp. 1-11.

Brust, Andreas, Wang, Ching-I.A., Daly, Norelle L., Kennerly, Joe, Sadeghi, Mahsa, Christie, Macdonald J., Lewis, Richard J., Mobli, Mehdi, and Alewood, Paul F. (2013) Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie International Edition, 52 (46). pp. 12020-12023.

Hardy, Margaret C., Daly, Norelle L., Mobli, Mehdi, Morales, Rodrigo A.V., and King, Glenn F. (2013) Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula. PLoS ONE, 8 (9). e73136. pp. 1-12.

Malagón, David, Botterill, Bonnie, Gray, Darren J., Lovas, Erica, Duke, Mary, Gray, Christian, Kopp, Steven R., Knott, Lyn M., McManus, Donald P., Daly, Norelle L., Mulvenna, Jason, Craik, David J., and Jones, Malcolm K. (2013) Anthelminthic activity of the cyclotides (kalata B1 and B2) against schistosome parasites. Peptide Science, 100 (5). pp. 461-470.

Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J., and Craik, David J. (2013) The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions. Peptide Science, 100 (5). pp. 453-460.

Quimbar, Pedro, Malik, Uru, Sommerhoff, Christian P., Kaas, Quentin, Chan, Lai Y., Huang, Yen-Hua, Grundhuber, Maresa, Dunse, Kerry, Craik, David J., Anderson, Marilyn A., and Daly, Norelle L. (2013) High-affinity cyclic peptide matriptase inhibitors. Journal of Biological Chemistry, 288 (19). pp. 13885-13896.

Conibear, Anne C., Rosengren, K. Johan, Daly, Norelle, Henriques, Sonia Troeira, and Craik, David J. (2013) The cyclic cystine ladder in θ-defensins is important for structure and stability, but not antibacterial activity. Journal of Biological Chemistry, 288 (15). pp. 10830-10840.

Chan, Lai Yue, Zhang, Veronica M., Huang, Yen-hua, Waters, Norman C., Bansal, Paramjit S., Craik, David J., and Daly, Norelle L. (2013) Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity. ChemBioChem, 14 (5). pp. 617-624.

Chan, Lai Yue, He, Wenjun, Tan, Ninghua, Zeng, Guangzhi, Craik, David J., and Daly, Norelle L. (2013) A new family of cystine knot peptides from the seeds of Momordica cochinchinensis. Peptides, 39. pp. 29-35.

Hashempour, Hossein, Koehbach, Johannes, Daly, Norelle L., Ghassempour, Alireza, and Gruber, Christian W. (2013) Characterizing circular peptides in mixtures: sequence fragment assembly of cyclotides from a violet plant by MALDI-TOF/TOF mass spectrometry. Amino Acids, 44 (2). pp. 581-595.

Inserra, Marco C., Kompella, Shiva N., Vetter, Irina, Brust, Andreas, Daly, Norelle L., Cuny, Hartmut, Craik, David J., Alewood, Paul F., Adams, David J., and Lewis, Richard J. (2013) Isolation and characterization of alpha-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology, 86 (6). pp. 791-799.

Eliasen, Rasmus, Daly, Norelle L., Wulff, Birgitte S., Adnresen, Thomas L., Conde-Frieboes, Kilian W., and Craik, David J. (2012) Design, synthesis, structural and functional characterization of novel melanocortin agonists based on the cyclotide kalata B1. Journal of Biological Chemistry, 287 (48). pp. 40493-40501.

Andersson, Håkan S., Figueredo, Sharel M., Haugaard-Kedström, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, André J., and Rosengren, K. Johan (2012) The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4). pp. 1471-1483.

Henrqiues, Sónia Troeira, Huang, Yen-Hua, Castanho, Miguel A.R.B., Bagatolli, Luis A., Sonza, Secondo, Tachedjian, Gilda, Daly, Norelle L., and Craik, David J. (2012) Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions. Journal of Biological Chemistry, 287 (40). pp. 33629-33643.

Hall, Kristopher, Lee, Tzong-Hsien, Daly, Norelle L., Craik, David J., and Aguilar, Marie-Isabel (2012) Gly6 of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes. Biochimica et Biophysica Acta. Biomembranes, 1818 (9). pp. 2354-2361.

Daly, Norelle, Wilson, David, and Craik, David (2012) Cyclic peptides from plants and their promise in drug design. Australian Biochemist, 43 (2). pp. 7-9.

Mylne, Joshua S., Chan, Lai Yue, Chanson, Aurelie H., Daly, Norelle L., Schaefer, Hanno, Bailey, Timothy L., Nguyencong, Philip, Cascales, Laura, and Craik, David J. (2012) Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis. Plant cell, 24 (7). pp. 2765-2778.

Clark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L., and Craik, David J. (2012) Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 (4). pp. 446-455.

Franco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams, David J., and Marí, Frank (2012) RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology, 83 (3). pp. 419-426.

Conibear, Anne C., Daly, Norelle L., and Craik, David J. (2012) Quantification of small cyclic disulfide-rich peptides. Peptide Science, 98 (6). pp. 518-524.

Chan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Nathalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J., and Daly, Norelle L. (2011) Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds. Blood, 118 (25). pp. 6709-6717.

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin, and Craik, David J. (2011) Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38). pp. 4242-4253.

Sando, Lillian, Henriques, Sonia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel, and Craik, David J. (2011) A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. ChemBioChem, 12 (16). pp. 2456-2462.

Smith, Amanda B., Daly, Norelle L., and Craik, David J. (2011) Cyclotides: a patent review. Expert Opinion on Therapeutic Patents, 21 (11). pp. 1657-1672.

Cascales, Laura, Henriques, Sonia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L., and Craik, David J. (2011) Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides. Journal of Biological Chemistry, 286 (42). pp. 36932-36943.

Halai, Reena, Callaghan, Brid, Daly, Norelle, Clark, Richard J., Adams, David J., and Craik, David J. (2011) Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19). pp. 6984-6992.

Dekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J., and Alewood, Paul F. (2011) α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40). pp. 15866-15869.

He, Wenjun, Chan, Lai Yue, Zeng, Guangzhi, Daly, Norelle, Craik, David J., and Tan, Ninghua (2011) Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides, 32 (8). pp. 1719-1723.

de Araujo, Aline Dantas, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J., and Alewood, Paul F. (2011) Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie International Edition, 50 (29). pp. 6527-6529.

Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A.R.B., Daly, Norelle L., and Craik, David J. (2011) Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27). pp. 24231-24241.

Hashempour, Hossein, Ghassempour, Alireza, Daly, Norelle, Spengler, Bernhard, and Römpp, Andreas (2011) Analysis of cyclotides in Viola ignobilis by Nano liquid chromatography fourier transform mass spectrometry. Protein and Peptide Letters, 18 (7). pp. 747-752.

Poth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L., and Craik, David J. (2011) Discovery of an unusual biosynthetic origin for circular proteins in legumes. Proceedings of the National Academy of Sciences of the United States of America, 108 (25). pp. 10127-10132.

Daly, Norelle L., and Craik, David J. (2011) Bioactive cystine knot proteins. Current opinion in chemical biology, 15 (3). pp. 362-368.

Mylne, Joshua S., Colgrave, Michelle L., Daly, Norelle, Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun, and Craik, David J. (2011) Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5). pp. 257-259.

Poth, Aaron G., Colgrave, Michelle L., Philip, Reynold, Kerenga, Bomai, Daly, Norelle L., Anderson, Marilyn A., and Craik, David J. (2011) Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chemical Biology, 6 (4). pp. 345-355.

Daly, Norelle L., Rosengren, K. Johan, Henriques, Sónia Troeira, and Craik, David J. (2011) NMR and protein structure in drug design: application to cyclotides and conotoxins. European Biophysics Journal, 40 (4). pp. 359-370.

Daly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J., and Craik, David J. (2011) Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12). pp. 10233-102377.

Lovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J., and Daly, Norelle L. (2011) Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization. Antioxidants & Redox Signaling, 14 (1). pp. 87-95.

Akcan, Muharrem, Stroud, Mark R., Hansen, Stacey J., Clark, Richard J., Daly, Norelle L., Craik, David J., and Olson, James M. (2011) Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3). pp. 782-787.

Morales, Rodrigo A.V., Daly, Norelle L., Vetter, Irina, Mobli, Mehdi, Napier, Ian A., Craik, David J., Lewis, Richard J., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., and Durek, Thomas (2010) Chemical synthesis and structure of the prokineticin Bv8. ChemBioChem, 11 (13). pp. 1882-1888.

Luo, Sulan, Akondi, Kalyana Bharati, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Christensen, Sean, Dowell, Cheryl, Daly, Norelle, Craik, David, Wang, Ching-I., Lewis, Richard J., Alewood, Paul F., and McIntosh, J. Michael (2010) Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the α3β2 nicotinic receptor. Journal of Biological Chemistry, 285 (16). pp. 12355-12366.

Muttenthaler, Markus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J., and Alewood, Paul F. (2010) Solving the α-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society, 132 (10). pp. 3514-3522.

Craik, David J., Mylne, Joshua S., and Daly, Norelle L. (2010) Cyclotides: macrocyclic peptides with applications in drug design and agriculture. Cellular and Molecular Life Sciences, 67 (1). pp. 9-16.

Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J., and Tan, Ninghua (2010) Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides, 31. pp. 1434-1440.

Ireland, David C., Clark, Richard J., Daly, Norelle L., and Craik, David J. (2010) Isolation, sequencing, and structure−activity relationships of cyclotides. Journal of Natural Products, 73 (9). pp. 1610-1622.

Plan, Manual R., Rosengren, K. Johan, Sando, Lillian, Daly, Norelle L., and Craik, David J. (2010) Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis. Peptide Science, 94 (5). pp. 647-658.

Lattin, Jane E., Greenwood, Kathryn P., Daly, Norelle L., Kelly, Gregory, Zidar, David A., Clark, Richard J., Thomas, Walter G., Kellie, Stuart, Craik, David J., Hume, David A., and Sweet, Matthew J. (2009) Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3). pp. 340-347.

Daly, Norelle L., Rosengren, K. Johan, and Craik, David J. (2009) Discovery, structure and biological activities of cyclotides. Advanced Drug Delivery Reviews, 61 (11). pp. 918-930.

Huang, Yen-Hua, Colgrave, Michelle L., Daly, Norelle, Keleshian, Asbed, Martinac, Boris, and Craik, David J. (2009) The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores. Journal of Biological Chemistry, 284 (31). pp. 20699-20707.

Haugaard-Jönsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Craik, David J., Wade, John D., and Rosengren, K. Johan (2009) Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework. Biochemical Journal, 419 (3). pp. 619-627.

Gunasekera, Sunithi, Daly, Norelle L., Clark, Richard J., and Craik, David J. (2009) Dissecting the oxidative folding of circular cystine knot miniproteins. Antioxidants & Redox Signaling, 11 (5). pp. 971-980.

Millard, Emma L., Nevin, Simon T., Loughnan, Marlon L., Nicke, Annette, Clark, Richard J., Alewood, Paul F., Lewis, Richard J., Adams, David J., Craik, David J., and Daly, Norelle L. (2009) Inhibition of neuronal nicotinic acetylcholine receptor subtypes by α-Conotoxin GID and analogues. Journal of Biological Chemistry, 284 (8). pp. 4944-4951.

Daly, Norelle L., and Craik, David J. (2009) Structural studies of conotoxins. IUBMB Life, 61 (2). pp. 144-150.

Chan, Lai Y., Wang, Conan K.L., Major, Jodie M., Greenwood, Kathryn P., Lewis, Richard J., Craik, David J., and Daly, Norelle L. (2009) Isolation and characterization of peptides from Momordica cochinchinensis seeds. Journal of Natural Products, 72 (8). pp. 1453-1458.

Gunasekera, Sunithi, Foley, Fiona M., Clark, Richard J., Sando, Lillian, Fabri, Louis J., Craik, David J., and Daly, Norelle L. (2008) Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides. Journal of Medicinal Chemistry, 51 (24). pp. 7697-7704.

Jin, Ai-Hua, Daly, Norelle L., Nevin, Simon T., Wang, Ching-I A., Dutertre, Sebastien, Lewis, Richard J., Adams, David J., Craik, David J., and Alewood, Paul F. (2008) Molecular engineering of conotoxins: the importance of loop size to α-conotoxin structure and function. Journal of Medicinal Chemistry, 51 (18). pp. 5575-5584.

Haugaard-Jönsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A.D., Wade, John D., Craik, David J., and Rosengren, K. Johan (2008) Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist. Journal of Biological Chemistry, 283 (95). pp. 23811-23818.

Imperial, Julita S., Chen, Ping, Sporning, Annett, Terlau, Heinrich, Daly, Norelle L., Craik, David J., Alewood, Paul F., and Olivera, Baldomero M. (2008) Tyrosine-rich conopeptides affect voltage-gated K+ channels. Journal of Biological Chemistry, 283 (34). pp. 23026-23032.

Hossain, Mohammed Akhter, Rosengren, K. Johan, Haugaard-Jönsson, Linda M., Zhang, Soude, Layfield, Sharon, Ferraro, Tania, Daly, Norelle L., Tregear, Geoffrey W., Wade, John D., and Bathgate, Ross A. D. (2008) The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors. Journal of Biological Chemistry, 283 (25). pp. 17287-17297.

Cemazar, Masa, Joshi, Ajinkya, Daly, Norelle L., Mark, Alan E., and Craik, David J. (2008) The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein. Structure, 16 (6). pp. 842-851.

Simonsen, Shane M., Sando, Lillian, Rosengren, K. Johan, Wang, Conan K., Colgrave, Michelle L., Daly, Norelle L., and Craik, David J. (2008) Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity. Journal of Biological Chemistry, 283 (15). pp. 9805-9813.

Dutertre, Sebastien, Croker, Daniel, Daly, Norelle L., Andersson, Asa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles, and Lewis, Richard J. (2008) Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides. Journal of Biological Chemistry, 283 (11). pp. 7100-7108.

Clark, Richard J., Daly, Norelle L., Halai, Reena, Nevin, Simon T., Adams, David J., and Craik, David J. (2008) The three-dimensional structure of the analgesic α-conotoxin, RgIA. FEBS Letters, 582 (5). pp. 597-602.

Daly, N., Ekberg, J.A., Thomas, L., Adams, D.J., Lewis, R.J., and Craik, D.J. (2004) Structures of muO-conotoxins from Conus marmoreus. Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. Journal of Biological Chemistry, 279 (24). pp. 25774-25782.

Rosengren, K. Johan, Wilson, David, Daly, Norelle L., Alewood, Paul F., and Craik, David J. (2002) Solution Structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche infensa sp. that contains a cystine-knot motif within its four disulfide bonds. Biochemistry, 41 (10). pp. 3294-3301.