Poole, Jessica, Hartley-Tassell, Lauren E., Day, Christopher J., Stanisic, Danielle I., Groves, Penny L., Chakravarty, Sumana, Lee Sim, B. Kim, Hoffman, Stephen L., Tiralongo, Joe, Bovin, Nicolai, Doolan, Denise L., and Jennings, Michael P. (2021) Identification of the glycan binding profile of human and rodent Plasmodium sporozoites. ACS Infectious Diseases, 7 (8). pp. 2383-2389.

Raja, Amber I., Cai, Yeping, Reiman, Jennifer M., Groves, Penny, Chakravarty, Sumana, McPhun, Virginia, Doolan, Denise L., Cockburn, Ian, Hoffman, Stephen L., Stanisic, Danielle I., and Good, Michael F. (2016) Chemically attenuated blood-stage Plasmodium yoelii parasites induce long-lived and strain-transcending protection. Infection and Immunity, 84 (8). pp. 2274-2288.

Hickey, Bradley W., Lumsden, Joanne M., Reyes, Sharina, Sedegah, Martha, Hollingdale, Michael R., Freilich, Daniel A., Luke, Thomas C., Charoenvit, Yupin, Goh, Lucy M., Berzins, Mara P., Bebris, Lolita, Sacci Jr., John B., De La Vega, Patricia, Wang, Ruobing, Ganeshan, Harini, Abot, Esteban N., Carucci, Daniel J., Doolan, Denise L., Brice, Gary T., Kumar, Anita, Aguiar, Joao, Nutman, Thomas B., Leitman, Susan F., Hoffman, Stephen L., Epstein, Judith E., and Richie, Thomas L. (2016) Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity. Malaria Journal, 15 (377). pp. 1-18.

Richie, Thomas L., Charoenvit, Yupin, Wang, Ruobing, Epstein, Judith E., Hedstrom, Richard C., Kumar, Sanjai, Luke, Thomas C., Freilich, Daniel A., Aguiar, Joao C., Sacci, Jr., John B., Sedegah, Martha, Nosek, Jr., Ronald A., De La Vega, Patricia, Berzins, Mara P., Majam, Victoria F., Abot, Esteban N., Ganeshan, Harini, Richie, Nancy O., Banania, Jo Glenna, Baraceros, Maria Fe B., Geter, Tanya, Mere, Robin, Bebris, Lolita, Limbach, Keith, Hickey, Bradley W., Lanar, David E., Ng, Jennifer, Shi, Meng, Hobart, Peter M., Norman, Jon A., Soisson, Lorraine A., Hollingdale, Michael R., Rogers, William O., Doolan, Denise L., and Hoffman, Stephen L. (2012) Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA. Human Vaccines & Immunotherapeutics, 8 (11). pp. 1564-1584.

Dobaño, Carlota, Sedegah, Martha, Rogers, William O., Kumar, Sanjai, Zheng, Hong, Hoffman, Stephen L., and Doolan, Denise L. (2009) Plasmodium: mammalian codon optimization of malaria plasmid DNA vaccines enhances antibody responses but not T cell responses nor protective immunity. Experimental Parasitology, 122 (2). pp. 112-123.

Dobaño, C., McTague, A., Sette, A., Hoffman, S.L., Rogers, W.O., and Doolan, D.L. (2007) Mutating the anchor residues associated with MHC binding inhibits and deviates CD8+ T cell mediated protective immunity against malaria. Molecular Immunology, 44 (9). pp. 2235-2248.

Doolan, Denise L., Southwood, Scott, Freilich, Daniel A., Sidney, John, Graber, Norma L., Shatney, Lori, Bebris, Lolita, Florens, Laurence, Dobano, Carlota, Witney, Adam A., Appella, Ettore, Hoffman, Stephen L., Yates, John R., Carucci, Daniel J., and Sette, Alessandro (2003) Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proceedings of the National Academy of Sciences of the United States of America, 100 (17). pp. 9952-9957.

Doolan, D.L., Aguiar, J.C., Weiss, W.R., Sette, A., Felgner, P.L., Regis, D.P., Quinones-Casas, P., Yates, J.R., Blair, P.L., Richie, T.L., Hoffman, S.L., and Carucci, D.J. (2003) Utilization of genomic sequence information to develop malaria vaccines. Journal of Experimental Biology, 206. pp. 3789-3802.

Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., Majam, Victoria F., Belmonte, Arnel, Lu, Minh, Belmonte, Maria, Carucci, Daniel J., and Hoffman, Stephen L. (2002) Persistence of protective immunity to malaria induced by DNA priming and poxvirus boosting: characterization of effector and memory CD8⁺-T-cell populations. Infection and Immunity, 70 (7). pp. 3493-3499.

Witney, Adam A., Doolan, Denise L., Anthony, Robert M., Weiss, Walter R., Hoffman, Stephen L., and Carucci, Daniel J. (2001) Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Molecular and Biochemical Parasitology, 118 (2). pp. 233-245.

Brice, Gary T., Graber, Norma L., Hoffman, Stephen L., and Doolan, Denise L. (2001) Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells. Journal of Immunological Methods, 257 (1-2). pp. 55-69.

Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon, and Hoffman, Stephen L. (2001) Induction of CD4⁺ T cell-dependent CD8⁺ type 1 responses in humans by a malaria DNA vaccine. Proceedings of the National Academy of Sciences of the United States of America, 98 (19). pp. 10817-10822.

Doolan, Denise L., and Hoffman, Stephen L. (2001) DNA-based vaccines against malaria: status and promise of the Multi-Stage Malaria DNA Vaccine Operation. International Journal for Parasitology, 31 (8). pp. 753-762.

Gramzinski, Robert A., Doolan, Denise L., Sedegah, Martha, Davis, Heather L., Krieg, Arthur M., and Hoffman, Stephen L. (2001) Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infection and Immunity, 69 (3). pp. 1643-1649.

Hoffman, Stephen L., and Doolan, Denise L. (2000) Malaria vaccines-targeting infected hepatocytes. Nature Medicine, 6 (11). pp. 1218-1219.

Ravichandran, Manickam, Doolan, Denise L., Cox-Singh, Janet, Hoffman, Stephen L., and Singh, Balbir (2000) HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 22 (9). pp. 469-473.

Le, Thong P., Coonan, Kevin M., Hedstrom, Richard C., Charoenvit, Yupin, Sedegah, Martha, Epstein, Judith E., Kumar, Sanjai, Wang, Ruobing, Doolan, Denise L., Maguire, Jason D., Parker, Suezanne E., Hobart, Peter, Norman, Jon, and Hoffman, Stephen L. (2000) Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers. Vaccine, 18 (18). pp. 1893-1901.

Wang, Ruobing, Doolan, Denise L., Le, Thong P., Hedstrom, Richard C., Coonan, Kevin M., Charoenvit, Yupin, Jones, Trevor R., Hobart, Peter, Margalith, Michal, Ng, Jennifer, Weiss, Walter R., Sedegah, Martha, de Taisne, Charles, Norman, Jon A., and Hoffman, Stephen L. (1998) Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science, 282 (5388). pp. 476-480.

Doolan, Denise L., Hoffman, Stephen L., Southwood, Scott, Wentworth, Peggy A., Sidney, John, Chesnut, Robert W., Keogh, Elissa, Appella, Ettore, Nutman, Thomas B., Lal, Altaf A., Gordon, Daniel M., Oloo, Aggrey, and Sette, Alessandro (1997) Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles. Immunity, 7 (1). pp. 97-112.

Gramzinski, Robert A., Maris, Dorina C., Doolan, Denise, Charoenvit, Yupin, Obaldia, Nicanor, Rossan, Richard, Sedegah, Martha, Wang, Ruobing, Hobart, Peter, Margalith, Michal, and Hoffman, Stephen (1997) Malaria DNA vaccines in Aotus monkeys. Vaccine, 15 (8). pp. 913-915.

Hoffman, Stephen L., Doolan, Denise L., Sedegah, Martha, Aguiar, Joao C., Wang, Ruobing, Malik, Anita, Gramzinski, Robert A., Weiss, Walter R., Hobart, Peter, Norman, Jon A., Margalith, Michal, and Hedstrom, Richard C. (1997) Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use. Vaccine, 15 (8). pp. 842-845.

Hedstrom, Richard C., Doolan, Denise L., Wang, Ruobing, Gardner, Malcolm J., Kumar, Anita, Sedegah, Martha, Gramzinski, Robert A., Sacci, John B., Charoenvit, Yupin, Weiss, Walter R., Margalith, Michal, Norman, Jon A., Hobart, Peter, and Hoffman, Stephen L. (1997) The development of a multivalent DNA vaccine for malaria. Springer Seminars in Immunopathology, 19 (2). pp. 147-159.

Doolan, D.L., and Hoffman, S.L. (1997) Multi-gene vaccination against malaria: a multistage, multi-immune response approach. Parasitology Today, 13 (5). pp. 171-178.

Hoffman, Stephen L., Doolan, Denise L., Sedegah, Martha, Wang, Ruobing, Scheller, Libia F., Kumar, Anita, Weiss, Walter R., Le, Thong P., Klinman, Dennis M., Hobart, Peter, Norman, Jon, and Hedstrom, Richard C. (1997) Toward clinical trials of DNA vaccines against malaria. Immunology and Cell Biology, 75. pp. 376-381.

Gardner, Malcolm J., Doolan, Denise L., Hedstrom, Richard C., Wang, Ruobing, Sedegah, Martha, Gramzinski, Robert A., Aguiar, Joao C., Wang, Helen, Margalith, Michal, Hobart, Peter, and Hoffman, Stephen L. (1996) DNA vaccines against malaria: immunogenicity and protection in a rodent model. Journal of Pharmaceutical Sciences, 85 (12). pp. 1294-1300.

Doolan, Denise L., Sedegah, Martha, Hedstrom, Richard C., Hobart, Peter, Charoenvit, Yupin, and Hoffman, Stephen L. (1996) Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon γ-, and nitric oxide-dependent immunity. The Journal of Experimental Medicine, 183 (4). pp. 1739-1746.

Doolan, Denise L., Wizel, Benjamin, and Hoffman, Stephen L. (1996) Class I HLA-restricted cytotoxic T lymphocyte responses against malaria-elucidation on the basis of HLA peptide binding motifs. Immunologic Research, 15 (4). pp. 280-305.

Hoffman, S.L., Doolan, D.L., Sedegah, M., Gramzinski, R., Wang, H., Gowda, K., Hobart, P., Margalith, M., Norman, J., and Hedstrom, R. (1995) Nucleic acid malaria vaccines. Annals of the New York Academy of Sciences, 772. pp. 88-94.