Publications by:
Jeffrey M. Bethony
Also publishes as (Jeffrey Bethony, Jeff Bethony, J.M. Bethony)
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Mairiang, Eimorn, Laha, Thewarach, Kaewkes, Sasithorn, Loukas, Alex, Bethony, Jeffrey, Brindley, Paul j., and Sripa, Banchob (2021) Hepatobiliary morbidities detected by ultrasonography in Opisthorchis viverrini-infected patients before and after praziquantel treatment: a five-year follow up study. Acta Tropica, 217. 105853.
Coghill, Anna, Proietti, Carla, Liu, Zhiwei, Krause, Lutz, Bethony, Jeff, Prokunina-Olsson, Ludmila, Obajemu, Adeola, Nkrumah, Francis, Biggar, Robert J., Bhatia, Kishor, Hildesheim, Allan, Doolan, Denise L., and Mbulaiteye, Sam M. (2020) The association between the comprehensive Epstein-Barr Virus serologic profile and endemic Burkitt lymphoma. Cancer Epidemiology, Biomarkers & Prevention, 29 (1). pp. 57-62.
Papatpremsiri, A., Junpue, P., Loukas, A., Brindley, P.J., Bethony, J.M., Sripa, B., and Laha, T. (2016) Immunization and challenge shown by hamsters infected with Opisthorchis viverrini following exposure to gamma-irradiated metacercariae of this carcinogenic liver fluke. Journal of Helminthology, 90 (1). pp. 39-47.
de Assis, Rafael Ramiro, Ludolf, Fernanda, Nakajima, Rie, Jasinskas, Al, Oliveira, Guilherme C., Felgner, Philip, Gaze Jangola, Soraya T., Loukas, Alex, LoVerde, Philip T., Bethony, Jeffrey M., Correa-Oliveira, Rodrigo, and Calzavara-Silva, Carlos E. (2016) A next-generation proteome array for Schistosoma mansoni. International Journal for Parasitology, 46 (7). pp. 411-415.
Worasith, Chanika, Kamamia, Christine, Yakovleva, Anna, Duenngai, Kunyarat, Wangboon, Chompunoot, Sithithaworn, Jiraporn, Watwiengkam, Nattaya, Namwat, Nisana, Techasen, Anchalee, Loilome, Watcharin, Yongvanit, Puangrat, Loukas, Alex, Sithithaworn, Paiboon, and Bethony, Jeffrey M. (2015) Advances in the diagnosis of human Opisthorchiasis: development of Opisthorchis viverrini antigen detection in urine. PLoS Neglected Tropical Diseases, 9 (10). e0004157. pp. 1-18.
Pearson, Mark S., Becker, Luke, Driguez, Patrick, Young, Neil D., Gaze Jangola, Soraya, Mendes, Tiago, Li, Xiao-Hong, Doolan, Denise L., Midzi, Nicholas, Mduluza, Takafira, McManus, Donald P., Wilson, R. Alan, Bethony, Jeffrey M., Nausch, Norman, Mutapi, Francisca, Felgner, Philip L., and Loukas, Alex (2015) Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Frontiers in Immunology, 6. 213. pp. 1-13.
Pearson, Mark S., Jariwala, Amar R., Abbenante, Giovanni, Plieskatt, Jordan, Wilson, David, Bottazzi, Maria Elena, Hotez, Peter J., Keegan, Brian, Bethony, Jeffrey M., and Loukas, Alex (2015) New tools for NTD vaccines: a case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Human Vaccines & Immunotherapeutics, 11 (5). pp. 1251-1257.
Chaiyadet, Sujittra, Sotillo, Javier, Smout, Michael, Cantacessi, Cinzia, Jones, Malcolm K., Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Potriquet, Jeremy, Laohaviroj, Marut, Mulvenna, Jason, Brindley, Paul J., Bethony, Jeffrey M., Laha, Thewarach, Sripa, Banchob, and Loukas, Alex (2015) Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype. Journal of Infectious Diseases, 212 (10). pp. 1636-1645.
Gaze, Soraya, Driguez, Patrick, Pearson, Mark S., Mendes, Tiago, Doolan, Denise L., Trieu, Angela, McManus, Donald P., Gobert, Geoffrey N., Periago, Maria Victoria, Correa Oliveira, Rodrigo, Cardoso, Fernanda C., Oliveira, Guilherme, Nakajima, Rie, Jasinskas, Al, Hung, Chris, Liang, Li, Pablo, Jozelyn, Bethony, Jeffrey M., Felgner, Philip L., and Loukas, Alex (2014) An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathogens, 10 (3). e1004033. pp. 1-16.
Tang, Yat T., Gao, Xin, Rosa, Bruce A., Abubucker, Sahar, Hallsworth-Pepin, Kymberlie, Martin, John, Tyagi, Rahul, Heizer, Esley, Zhang, Xu, Bhonagiri-Palsikar, Veena, Minx, Patrick, Warren, Wesley C., Wang, Qi, Zhan, Bin, Hotez, Peter J., Sternberg, Paul W., Dougall, Annette, Gaze, Soraya Torres, Mulvenna, Jason, Sotillo, Javier, Ranganathan, Shoba, Rabelo, Elida M., Wilson, Richard K., Felgner, Philip L., Bethony, Jeffrey, Hawdon, John M., Gasser, Robin B., Loukas, Alex, and Mitreva, Makedonka (2014) Genome of the human hookworm Necator americanus. Nature Genetics, 46 (3). pp. 261-271.
Hotez, Peter J., Diemert, David, Bacon, Kristina M., Beaumier, Coreen, Bethony, Jeffrey M., Bottazzi, Maria Elena, Brooker, Simon, Couto, Artur Roberto, da Silva Freire, Marcos, Homma, Akira, Lee, Bruce Y., Loukas, Alex, Loblack, Marva, Morel , Carlos Medicis, Oliveira, Rodrigo Correa, and Russell, Philip K. (2013) The human hookworm vaccine. Vaccine, 31 (Supplement 2). B227-B232.
Gaze, Soraya, McSorley, Henry J., Daveson, James, Jones, Di, Bethony, Jeffrey M., Oliveira, Luciana M., Speare, Richard, McCarthy, James S., Engwerda, Christian R., Croese, John, and Loukas, Alex (2012) Characterising the mucosal and systemic immune responses to experimental human hookworm infection. PLoS Pathogens, 8 (2). e1002520. pp. 1-11.
Pearson, Mark S., Tribolet, Leon, Cantacessi, Cinzia, Periago, Maria Victoria, Adela Valerio, Maria, Jariwala, Amar R., Hotez, Peter, Diemert, David, Loukas, Alex, and Bethony, Jeffrey (2012) Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. Journal of Allergy and Clinical Immunology, 130 (1). pp. 13-21.
Mairiang, Eimorn, Laha, Thewarach, Bethony, Jeffrey M., Thinkhamrop, Bandit, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Tesana, Smarn, Loukas, Alex, Brindley, Paul J., and Sripa, Banchob (2012) Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand. Parasitology International, 61 (1). pp. 208-211.
Mulvenna, Jason, Yonglitthipagon, Ponlapat, Sripa, Banchob, Brindley, Paul J., Loukas, Alex, and Bethony, Jeffrey M. (2012) Banking on the future: biobanking for "omics" approaches to biomarker discovery for Opisthorchis-induced cholangiocarcinoma in Thailand. Parasitology International, 61 (1). pp. 173-177.
Sripa, Banchob, Thinkhamrop, Bandit, Mairiang, Eimorn, Laha, Thewarach, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Periago, Maria Victoria, Bhudhisawasdi, Vajarabhongsa, Yonglitthipagon, Ponlapat, Mulvenna, Jason, Brindley, Paul J., Loukas, Alex, and Bethony, Jeffrey M. (2012) Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 6 (5). e1654. pp. 1-9.
Pearson, Mark S., Pickering, Darren A., McSorley, Henry J., Bethony, Jeffrey M., Tribolet, Leon, Dougall, Annette M., Hotez, Peter J., and Loukas, Alex (2012) Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Neglected Tropical Diseases, 6 (3). e1564. pp. 1-10.
Diemert, David J., Pinto, Antonio G., Freire, Janaina, Jariwala, Amar, Santiago, Helton, Hamilton, Robert G., Periago, Maria Victoria, Loukas, Alex, Tribolet, Leon, Mulvenna, Jason, Correa-Oliveira, Rodrigo, Hotez, Peter J., and Bethony, Jeffrey M. (2012) Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. Journal of Allergy and Clinical Immunology, 130 (1). pp. 169-176.
Yonglitthipagon, Ponlapat, Pairojkul, Chawalit, Chamgramol, Yaovalux, Loukas, Alex, Mulvenna, Jason, Bethony, Jeffrey, Bhudhisawasdi, Vajarabhongsa, and Sripa, Banchob (2012) Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin binding phosphoprotein 50 in cholangiocarcinoma. Human Pathology, 43 (10). pp. 1719-1730.
Loukas, Alex, Gaze, Soraya, Pearson, Mark, Doolan, Denise, Felgner, Philip, Diemert, David, McManus, Donald P., Driguez, Patrick, and Bethony, Jeffrey (2012) Schistosomiasis vaccines: new approaches to antigen discovery and promising new candidates. In: Caffrey, Conor R., (ed.) Parasitic Helminths: targets, screens, drugs and vaccines. Drug Discovery in Infectious Diseases . Wiley-Blackwell, Weinheim, Germany, pp. 421-433.
Sripa, Banchob, Brindley, Paul J., Mulvenna, Jason, Laha, Thewarach, Smout, Michael J., Mairiang, Eimorn, Bethony, Jeffrey M., and Loukas, Alex (2012) The tumorigenic liver fluke Opisthorchis viverrini - multiple pathways to cancer. Trends in Parasitology, 28 (10). pp. 395-407.
Loukas, Alex, Gaze, Soraya, Mulvenna, Jason, Gasser, Robin, Brindley, Paul, Doolan, Denise, Bethony, Jeffrey, Jones, Malcolm, Gobert, Geoffrey, Drigues, Patrick, McManus, Donald, and Hotez, Peter (2011) Vaccinomics for the major blood feeding helminths of humans. OMICS: a Journal of Integrative Biology, 15 (11). pp. 567-577.
Sripa, Banchob, Bethony, Jeffrey, Sithithaworn, Paiboon, Kaewkes, Sasithorn, Mairiang, Eimorn, Loukas, Alex, Mulvenna, Jason, Laha, Thewarach, Hotez, Peter, and Brindley, Paul (2011) Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Tropica, 120 (Supp 1). S158-S168.
Bethony, Jeffrey M., Cole, Rhea N., Guo, Xiaoti, Kamhawi, Shaden, Lightowlers, Marshall W., Loukas, Alex, Petri, William, Reed, Steven, Valenzuela, Jesus G., and Hotez, Peter J. (2011) Vaccines to combat the neglected tropical diseases. Immunological Reviews, 239 (1). pp. 237-270.
Smout, Michael J., Sripa, Banchob, Laha, Thewarach, Mulvenna, Jason, Gasser, Robin B. , Young, Neil D., Bethony, Jeffrey M., Brindley, Paul J., and Loukas, Alex (2011) Infection with the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular BioSystems, 7 (5). pp. 1367-1375.
Hotez, Peter J., Bethony, Jeffrey M., Diemert, David J., Pearson, Mark, and Loukas, Alex (2010) Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews Microbiology , 8 (11). pp. 814-826.
Pearson, Mark S., Pickering, Darren A., Tribolet, Leon, Cooper, Leanne, Mulvenna, Jason, Oliveira, Luciana M., Bethony, Jeffrey M., Hotez, Peter J., and Loukas, Alex (2010) Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm Infection and schistosomiasis. Journal of Infectious Diseases, 201 (10). pp. 1561-1569.
Zhan, Bin, Perally, Samirah, Brophy, Peter M., Xue, Jian, Goud, Gaddam, Liu, Sen, Deumic, Vehid, de Oliveira, Luciana M., Bethony, Jeffrey, Bottazzi, Maria Elena, Jiang, Desheng, Gillespie, Portia, Xiao, Shu-hua, Gupta, Richi, Loukas, Alex, Ranjit, Najju, Lustigman, Sara, Oksov, Yelena, and Hotez, Peter (2010) Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infection and Immunity, 78 (4). pp. 1552-1563.
Sripa, Banchob, Mairiang, Eimorn, Thinkhamrop, Bandit, Laha, Thewarach, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Tessana, Smarn, Loukas, Alex, Brindley, Paul J., and Bethony, Jeffrey M. (2009) Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6. Hepatology, 50 (4). pp. 1273-1281.
Pearson, Mark S., Bethony, Jeffrey M., Pickering, Darren A., de Oliveira, Luciana M., Jariwala, Amar, Santiago, Helton, Miles, Aaron P., Zhan, Bin, Jiang, Desheng, Ranjit, Najju, Mulvenna, Jason, Tribolet, Leon, Plieskatt, Jordan, Smith, Tracey, Bottazzi, Maria Elena, Jones, Kathryn, Keegan, Brian, Hotez, Peter J., and Loukas, Alex (2009) An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB Journal, 23 (9). pp. 3009-3017.
Teixeira-Carvalho, Andréa, Fujiwara, Ricardo T., Stemmy, Erik J., Olive, Denise, Damsker, Jesse M., Loukas, Alex, Correa-Oliveira, Rodrigo, Constant, Stephanie L., and Bethony, Jeffrey M. (2008) Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Infection and Immunity, 76 (12). pp. 5810-5816.
Hotez, Peter J., Bethony, Jeffrey M., Oliveira, Sergio, Brindley, Paul J., and Loukas, Alex (2008) Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines, 7 (6). pp. 745-752.
Bethony, Jeffrey M., and Loukas, Alex (2008) The Schistosomiasis research agenda: what now? PLoS Neglected Tropical Disease, 2 (2). e207. pp. 1-2.
Bethony, Jeffrey M., Diemert, David J., Oliveira, Sergio Costa, and Loukas, Alex (2008) Can schistosomiasis really be consigned to history without a vaccine? Vaccine, 26 (27-28). pp. 3373-3376.
Don, Tegan A., Bethony, Jeffrey M., and Loukas, Alex (2008) Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections. International Journal of Infectious Diseases, 12 (6). e39-e47.
Sripa, Banchob, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Mairiang, Eimorn, Laha, Thewarach, Smout, Michael, Pairojkul, Chawalit, Bhudhisawasdi, Vajaraphongsa, Tesana, Smarn, Thinkamrop, Bandit, Bethony, Jeffrey M., Loukas, Alex, and Brindley, Paul J. (2007) Liver fluke induces Cholangiocarcinoma. PLoS Medicine, 4 (7). 201. pp. 1148-1155.
Tran, Mai H., Pearson, Mark S., Bethony, Jeffrey M., Smyth, Danielle J., Jones, Malcolm K., Duke, Mary, Don, Tegan A., McManus, Donald P., Correa-Oliveira, Rodrigo, and Loukas, Alex (2006) Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nature Medicine, 12 (7). pp. 835-840.
Bethony, Jeffrey, Loukas, Alex, Smout, Michael, Brooker, Simon, Mendez, Susana, Plieskatt, Jordan, Goud, Gaddam, Bottazzi, Maria Elena, Zhan, Bin, Wang, Yan, Williamson, Angela, Lustigman, Sara, Correa-Oliveira, Rodrigo, Xiao, Shuhua, and Hotez, Peter J. (2005) Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB Journal, 19 (12). pp. 1743-1745.