Publications by: Patrick M. Schaeffer

Also publishes as (Patrick Schaeffer, P.M. Schaeffer)

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Number of items: 45.

Toft, Casey J., Bourquin, Rebecca A., Sorenson, Alanna E., Horwood, Paul F., Druce, Julian, and Schaeffer, Patrick M. (2023) Analytical sensitivity of COVID-19 rapid antigen tests: A case for a robust reference standard. Talanta, 7. 100187.

Radford, Holly M., Toft, Casey J., Sorenson, Alanna E., and Schaeffer, Patrick M. (2023) Inhibition of Replication Fork Formation and Progression: Targeting the Replication Initiation and Primosomal Proteins. International Journal of Molecular Sciences, 24 (10). 8802.

Sorenson, Alanna E., and Schaeffer, Patrick M. (2023) Real-Time Temperature Sensing Using a Ratiometric Dual Fluorescent Protein Biosensor. Biosensors, 13 (3). 338.

Toft, Casey J., Sorenson, Alanna E., and Schaeffer, Patrick M. (2022) Rise of the terminator protein tus: A versatile tool in the biotechnologist's toolbox. Analytica Chimica Acta, 1213. 339946.

Toft, Casey J., Sorenson, Alanna E., and Schaeffer, Patrick M. (2022) A soft Tus-Ter interaction is hiding a fail-safe lock in the replication fork trap of Dickeya paradisiaca. Microbiological Research, 263. 127147.

Toft, Casey, Moreau, Morgane J.J., Perutka, Jiri, Mandapati, Savitri, Enyeart, Peter, Sorenson, Alanna E., Ellington, Andrew, and Schaeffer, Patrick M. (2021) Delineation of the ancestral tus-dependent replication fork trap. International Journal of Molecular Sciences, 22 (24). 13533.

Sorenson, Alanna E., and Schaeffer, Patrick M. (2020) Electrophoretic mobility shift assays with GFP-tagged proteins (GFP-EMSA). In: Labrou, Nikolaos E., (ed.) Targeting Enzymes for Pharmaceutical Development. Methods in Molecular Biology, 2089 . Springer, New York, NY, USA, pp. 159-166.

Sorenson, Alanna E., and Schaeffer, Patrick M. (2020) High-throughput differential scanning fluorimetry of GFP-tagged proteins. In: Labrou, Nikolaos E., (ed.) Targeting Enzymes for Pharmaceutical Development. Methods in Molecular Biology, 2089 . Springer, New York, NY, USA, pp. 69-85.

Sorenson, A.E., and Schaeffer, P.M. (2020) A new bivalent fluorescent fusion protein for differential Cu(II) and Zn(II) ion detection in aqueous solution. Analytica Chimica Acta, 1101. pp. 120-128.

Johnston, Elecia B., Kamath, Sandip D., Iyer, Swati P., Pratap, Kunal, Karnaneedi, Shaymaviswanathan, Taki, Aya C., Nugraha, Roni, Schaeffer, Patrick M., Rolland, Jennifer M., O'Hehir, Robyn E., and Lopata, Andreas L. (2019) Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults. Molecular Immunology, 112. pp. 330-337.

Razaghi, Ali, Heimann, Kirsten, Schaeffer, Patrick M., and Gibson, Spencer B. (2018) Negative regulators of cell death pathways in cancer: perspective on biomarkers and targeted therapies. Apoptosis, 23 (2). pp. 93-112.

Askin, Samuel, Bond, Thomas E.H., Sorenson, Alanna E., Moreau, Morgane J.J., Antony, Helma, Davis, Rohan A., and Schaeffer, Patrick M. (2018) Selective protein unfolding: a universal mechanism of action for the development of irreversible inhibitors. Chemical Communications, 54 (14). pp. 1738-1741.

Bond, Thomas E.H., Sorenson, Alanna E., and Schaeffer, Patrick M. (2017) Functional characterisation of Burkholderia pseudomallei biotin protein ligase: a toolkit for anti-melioidosis drug development. Microbiological Research, 199. pp. 40-48.

Kamath, Sandip, Johnston, Elecia, Iyer, Swati, Schaeffer, Patrick, Koplin, Jennifer, Allen, Katrina, and Lopata, Andreas (2017) IgE reactivity to shrimp allergens in infants and their cross-reactivity to house dust mite. Pediatric Allergy and Immunology, 28 (7). pp. 703-707.

Bond, Thomas E.H., Sorenson, Alanna E., and Schaeffer, Patrick M. (2017) A green fluorescent protein-based assay for high-throughput ligand-binding studies of a mycobacterial biotin protein ligase. Microbiological Research, 205. pp. 35-39.

Askin, Samuel P., Bond, Thomas E.H., and Schaeffer, Patrick M. (2016) Green fluorescent protein-based assays for high-throughput functional characterization and ligand-binding studies of biotin protein ligase. Analytical Methods, 8 (2). pp. 418-424.

Sorenson, Alanna E., Askin, Samuel P., and Schaeffer, Patrick M. (2015) In-gel detection of biotin–protein conjugates with a green fluorescent streptavidin probe. Analytical Methods, 7. pp. 2087-2092.

Johnston, Elecia B., Kamath, Sandip D., Lopata, Andreas L., and Schaeffer, Patrick M. (2014) Tus-Ter-lock immuno-PCR assays for the sensitive detection of tropomyosin-specific IgE antibodies. Bioanalysis, 6 (4). pp. 465-476.

Sorenson, Alanna E., Williams, Natasha L., Morris, Jodie L., Ketheesan, Natkunam, Norton, Robert E., and Schaeffer, Patrick M. (2013) Improved diagnosis of melioidosis using a 2-dimensional immunoarray. Diagnostic Microbiology and Infectious Disease, 77 (3). pp. 209-215.

Cooper, Alanna, Williams, Natasha L., Morris, Jodie L., Norton, Robert E., Ketheesan, Natkunam, and Schaeffer, Patrick M. (2013) ELISA and immuno–polymerase chain reaction assays for the sensitive detection of melioidosis. Diagnostic Microbiology and Infectious Disease, 75 (2). pp. 135-138.

Moreau, Morgane J.J., and Schaeffer, Patrick M. (2013) Dissecting the salt dependence of the Tus-Ter protein-DNA complexes by high-throughput differential scanning fluorimetry of a GFP-tagged Tus. Molecular BioSystems, 9 (12). pp. 3146-3154.

Antony, Helma, and Schaeffer, Patrick M. (2013) A GFP-tagged nucleoprotein-based aggregation assay for anti-influenza drug discovery and antibody development. The Analyst, 138 (20). pp. 6073-6080.

Morin, Isabelle, and Schaeffer, Patrick M. (2012) Combining RNA-DNA swapping and quantitative polymerase chain reaction for the detection of influenza A nucleoprotein. Analytical Biochemistry, 420 (2). pp. 121-126.

Moreau, Morgane J.J., and Schaeffer, Patrick M. (2012) Differential Tus–Ter binding and lock formation: implications for DNA replication termination in Escherichia coli. Molecular BioSystems, 8 (10). pp. 2783-2791.

Moreau, Morgane J.J., Morin, Isabelle, Askin, Samuel P., Cooper, Alanna, Moreland, Nicole J., Vasudevan, Subhash G., and Schaeffer, Patrick M. (2012) Rapid determination of protein stability and ligand binding by differential scanning fluorimetry of GFP-tagged proteins. RSC Advances, 2 (31). pp. 11892-11900.

Moreau, Morgane J.J, and Schaeffer, Patrick M. (2012) A polyplex qPCR-based binding assay for protein–DNA interactions. Analyst, 137. pp. 4111-4113.

Askin, Samuel P., and Schaeffer, Patrick M. (2012) A universal immuno-PCR platform for comparative and ultrasensitive quantification of dual affinity-tagged proteins in complex matrices. Analyst, 137 (22). pp. 5193-5196.

Askin, Samuel P., Morin, Isabelle, and Schaeffer, Patrick M. (2011) Development of a protease activity assay using heat-sensitive Tus-GFP fusion protein substrates. Analytical Biochemistry, 415 (2). pp. 126-133.

Morin, Isabelle, Askin, Samuel P., and Schaeffer, Patrick M. (2011) IgG-detection devices for the Tus-Ter-lock immuno-PCR diagnostic platform. Analyst, 136 (22). pp. 4815-4821.

Moreau, Morgane J.J., Morin, Isabelle, and Schaeffer, Patrick M. (2010) Quantitative determination of protein stability and ligand binding using a green fluorescent protein reporter system. Molecular BioSystems, 6 (7). pp. 1285-1292.

Morin, Isabelle, Dixon, Nicholas E., and Schaeffer, Patrick M. (2010) Ultrasensitive detection of antibodies using a new Tus-Ter-lock immunoPCR system. Molecular BioSystems, 6 (7). pp. 1173-1175.

Dahdah, Dahdah B., Morin, Isabelle, Moreau, Morgane J.J., Dixon, Nicholas E., and Schaeffer, Patrick M. (2009) Site-specific covalent attachment of DNA to proteins using a photoactivatable Tus–Ter complex. Chemical Communications, 21. pp. 3050-3052.

Schaeffer, Patrick, and Dixon, Nicholas (2009) Synthesis and applications of covalent protein-DNA conjugates. Australian Journal of Chemistry, 62 (10). pp. 1328-1332.

Schaeffer, Patrick, and Dixon, N.E. University of Wollongong and James Cook University (2008) Diagnostics in monoplex/multiplex. WO 2008 148143 A1 .

Tanner, Nathan A., Hamdan, Samir M., Jergic, Slobodan, Loscha, Karin V., Schaeffer, Patrick M., Dixon, Nicholas E., and van Oijen, Antoine M. (2008) Single-molecule studies of fork dynamics in Escherichia coli DNA replication. Nature Structural and Molecular Biology, 15 (2). pp. 170-176.

Watt, Stephen J., Urathamakul, Thitima, Schaeffer, Patrick M., Williams, Neal K., Sheil, Margaret M., Dixon, Nicholas E., and Beck, Jennifer L. (2007) Multiple oligomeric forms of Escherichia coli DnaB helicase revealed by electrospray ionisation mass spectrometry. Rapid Communications in Mass Spectrometry, 21. pp. 132-140.

Su, Xun-Cheng, Schaeffer, Patrick M., Loscha, Karin V., Gan, Pamela H. P., Dixon, Nicholas E. , and Otting, Gottfried (2006) Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase. FEBS journal, 273 (21). pp. 4997-5009.

Ioannou, Charikleia, Schaeffer, Patrick M., Dixon, Nicholas E., and Soultanas, Panos (2006) Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis. Nucleic Acids Research, 34 (18). pp. 5247-5258.

Dixon, Nicholas, Schaeffer, Patrick, and Mulcair, Mark Australian National University (2006) Double-stranded oligonucleotides and uses therefor. WO 2006 081623 A1 .

Mulcair, Mark D., Schaeffer, Patrick M., Oakley, Aaron J., Cross, Hannah F., Neylon, Cameron, Hill, Thomas M., and Dixon, Nicholas E. (2006) A molecular mousetrap determines polarity of termination of DNA replication in E. coli. Cell, 125 (7). pp. 1309-1319.

Beck, Jennifer L., Urathamakul, Thitima, Watt, Stephen J., Sheil, Margaret M., Schaeffer, Patrick M., and Dixon, Nicholas E. (2006) Proteomic dissection of DNA polymerization. Expert Review of Proteomics, 3 (2). pp. 197-211.

Graham, Stephen C., Lilley, Penelope E., Lee, Mihwa, Schaeffer, Patrick M., Kralicek, Andrew V., Dixon, Nicholas E., and Guss, J. Mitchell (2006) Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: insights into substrate recognition and the mechanism of catalysis. Biochemistry, 45 (3). pp. 964-975.

Robinson, Andrew, Wu, Peter S.-C., Harrop, Stephen J. , Schaeffer, Patrick M. , Dosztanyi, Zsuzsanna, Gillings, Michael R., Holmes, Andrew J. , Nevalainen, K. M. Helena, Stokes, H. W., Otting, Gottfried, Dixon, Nicholas E., Curmi, Paul M. G., and Mabbutt, Bridget C. (2005) Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable α+β barrel family. Journal of Molecular Biology, 346 (5). pp. 1229-1241.

Oakley, Aaron J., Loscha, Karin V., Schaeffer, Patrick M., Liepinsh, Edvards, Pintacuda, Guido, Wilce, Matthew C.J., Otting, Gottfried, and Dixon, Nicholas E. (2005) Crystal and solution structures of the helicase-binding domain of Escherichia coli primase. Journal of Biological Chemistry, 280 (12). pp. 11495-11504.

Schaeffer, Patrick M., Headlam, Madeleine J., and Dixon, Nicholas E. (2005) Protein - protein interactions in the eubacterial replisome. IUBMB Life, 57 (1). pp. 5-12.

This list was generated on Thu Apr 25 13:52:03 2024 AEST.