Publications by: Ulf Schmitz

Also publishes as (U. Schmitz)

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Number of items: 50.

Thavaneswaran, Subotheni, Kansara, Maya, Lin, Frank, Espinoza, David, Grady, John P., Lee, Chee Khoon, Ballinger, Mandy L., Sebastian, Lucille, Corpuz, Theresa, Qiu, Min Ru, Mundra, Piyushkumar, Bailey, Charles G., Schmitz, Ulf, Simes, John, Joshua, Anthony M., and Thomas, David M. (2023) A signal-seeking Phase 2 study of olaparib and durvalumab in advanced solid cancers with homologous recombination repair gene alterations. British Journal of Cancer. (In Press)

Gillman, Rhys, Field, Matt A., Schmitz, Ulf, Karamatic, Rozemary, and Hebbard, Lionel (2023) Identifying cancer driver genes in individual tumours. Computational and Structural Biotechnology Journal, 21. pp. 5028-5038.

Sadeghi, Mehdi, Karimi, Mohammad Reza, Karim, Amir Hossein, Farshbaf, Nafiseh Ghorbanpour, Barzegar, Abolfazl, and Schmitz, Ulf (2023) Network-Based and Machine-Learning Approaches Identify Diagnostic and Prognostic Models for EMT-Type Gastric Tumors. Genes, 14 (750).

Schmitz, Ulf (2023) Overview of Computational and Experimental Methods to Identify Tissue-Specific MicroRNA Targets. In: Dalmay, Tamas, (ed.) MicroRNA Detection and Target Identification. Methods in Molecular Biology, 2630 . Humana Press, New York, NY, USA, pp. 155-177.

Dorney, Ryley, Dhungel, Bijay P., Rasko, John E.J., Hebbard, Lionel, and Schmitz, Ulf (2023) Recent Advances in Cancer Fusion Transcript Detection. Briefings in Bioinformatics, 24 (1). bbac519.

Wu, Siyuan, and Schmitz, Ulf (2023) Single-cell and long-read sequencing to enhance modelling of splicing and cell-fate determination. Computational and Structural Biotechnology Journal, 21. pp. 2373-2380.

Wong, Alex C.H., Wong, Justin J.-L., Rasko, John E.J., and Schmitz, Ulf (2023) SpliceWiz: Interactive analysis and visualization of alternative splicing in R. Briefings in Bioinformatics, 25 (1).

Oehler, Josphine B., Wright, Helen, Stark, Zornitza, Mallett, Andrew, and Schmitz, Ulf (2023) The application of long‑read sequencing in clinical settings. Human Genomics, 17. 73.

Petrova, Veronika, Song, Renhua, DEEP Consortium, , Nordström, Karl J.V., Walter, Jörn, Wong, Justin J.-L., Armstrong, Nicola J., Rasko, John E.J., and Schmitz, Ulf (2022) Increased chromatin accessibility facilitates intron retention in specific cell differentiation states. Nucleic Acids Research, 50 (20). gkac994. pp. 11563-11579.

Wong, Justin J.L., and Schmitz, Ulf (2022) Intron retention: importance, challenges, and opportunities. Trends in Genetics, 38 (8). pp. 789-792.

Karimi, Mohammad Reza, Karimi, Amir Hossein, Abolmaali, Shamsozoha, Mehdi, Sadeghi, and Schmitz, Ulf (2022) Prospects and challenges of cancer systems medicine: from genes to disease networks. Briefings in Bioinformatics, 23 (1). bbab343.

Lai, Xin, Schmitz, Ulf, and Vera, Julio (2022) The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective. In: Schmitz, Ulf, Wolkenhauer, Olaf, and Vera, Julio, (eds.) The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective. Advances in Experimental Medicine and Biology, 1385 . Springer, Cham, pp. 1-22.

Schmitz, Ulf, Wolkenhauer, Olaf, and Vera-González, Julio (2022) Systems Biology of MicroRNAs in Cancer. Advances in Experimental Medicine and Biology, 1385 . Springer Cham.

Shah, Jaynish S., Milevskiy, Michael J.G., Petrova, Veronika, Au, Amy Y.M., Wong, Justin J.L., Visvader, Jane E., Schmitz, Ulf, and Rasko, John E.J. (2022) Towards resolution of the intron retention paradox in breast cancer. Breast Cancer Research, 24. 100.

Alharbi, Adel B., Schmitz, Ulf, Bailey, Charles G., and Rasko, John E.J. (2021) CTCF as a regulator of alternative splicing: new tricks for an old player. Nucleic Acids Research, 49 (14). pp. 7825-7838.

Schmitz, Ulf, Monteuuis, Geoffray, Petrova, Veronika, Shah, Jaynish S., and Rasko, John E.J. (2021) Computational methods for intron retention identification and quantification. In: Wolkenhauer, Olaf, Cai, Yudong, and Rozman, Damjana, (eds.) Systems Medicine: integrative, qualitative and computational approaches. Academic Press, London Wall, United Kingdom, pp. 63-74.

Bailey, Charles G., Gupta, Shailendra, Metierre, Cynthia, Amarasekera, Punkaja M.S., O'Young, Patrick, Kyaw, Wunna, Laletin, Tatyana, Francis, Habib, Semaan, Crystal, Sharifi Tabar, Mehdi, Singh, Krishna P., Mullighan, Charles G., Wolkenhauer, Olaf, Schmitz, Ulf, and Rasko, John (2021) Structure–function relationships explain CTCF zinc finger mutation phenotypes in cancer. Cellular and Molecular Life Sciences, 78. pp. 7519-7536.

Dhungel, Bijay P., Monteuuis, Geoffray, Giardina, Caroline, Tabar, Mehdi S., Feng, Yue, Metierre, Cynthia, Ho, Sarah, Nagarajah, Rajini, Fontaine, Angela R.M., Shah, Jaynish S., Gokal, Divya, Bailey, Charles G., Schmitz, Ulf, and Rasko, John E.J. (2021) The fusion of CLEC12A and MIR223HG arises from a trans‐splicing event in normal and transformed human cells. International Journal of Molecular Sciences, 22. 12178.

Schmitz, Ulf, Shah, Jaynish S., Dhungel, Bijay P., Monteuuis, Geoffray, Luu, Phuc-Loi, Petrova, Veronika, Metierre, Cynthia, Nair, Shalima S., Bailey, Charles G., Saunders, Verity A., Turhan, Ali G., White, Deborah L., Branford, Susan, Clark, Susan J., Hughes, Timothy P., Wong, Justin J.-L., and Rasko, John E.J. (2020) Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukaemia patients. Cancers, 12 (12). 3738.

Alharbi, Adel B., Schmitz, Ulf, Marshall, Amy D., Vanichkina, Darya, Nagarajah, Rajini, Vellozzi, Melissa, Wong, Justin J.L., Bailey, Charles G., and Rasko, John E.J. (2020) Ctcf haploinsufficiency mediates intron retention in a tissue-specific manner. RNA Biology, 18 (1). pp. 93-103.

Aghajani, Marra Jai, Yang, Tao, Schmitz, Ulf, James, Alexander, McCafferty, Charles Eugenio, de Souza, Paul, Niles, Navin, and Roberts, Tara L. (2020) Epithelial-to-mesenchymal transition and its association with PD-L1 and CD8 in thyroid cancer. Endocrine Connections, 9. pp. 1028-1041.

Monteuuis, Geoffray, Schmitz, Ulf, Petrova, Veronika, Kearney, Padraic S., and Rasko, John E.J. (2020) Holding on to junk bonds: intron retention in cancer and therapy. Cancer Research, 81 (4). pp. 779-789.

Green, Immanuel D., Pinello, Natalia, Song, Renhua, Lee, Quitin, Halsted, James M., Kwok, Chau-To, Wong, Alex C. H., Nair, Shalima S., Clark, Susan J., Roediger, Ben, Schmitz, Ulf, Larance, Mark, Hayashi, Rippei, Rasko, John E. J., and Wong, Justin J.-L. (2020) Macrophage development and activation involve coordinated intron retention in key inflammatory regulators. Nucleic Acids Research, 48 (12). pp. 6513-6529.

Emran, Abdullah Al, Nsengimana, Jérémie, Punnia-Moorthy, Gaya, Schmitz, Ulf, Gallagher, Stuart J., Newton-Bishop, Julia, Tiffen, Jessamy C., and Hersey, Peter (2020) Study of the female sex survival advantage in melanoma—a focus on x-linked epigenetic regulators and immune responses in two cohorts. Cancers, 12. 2082.

Schmitz, Ulf, Gupta, Shailendra K., Vera, Julio, and Wolkenhauer, Olaf (2019) Computational approaches in microRNA biology. In: Narayan, Roger, (ed.) Encyclopedia of Biomedical Engineering. Elsevier, Amsterdam, The Netherlands, pp. 317-330.

Naderi-Meshkin, Hojjat, Lai, Xin, Amirkhah, Raheleh, Vera, Julio, Rasko, John E.J., and Schmitz, Ulf (2019) Exosomal lncRNAs and cancer: Connecting the missing links. Bioinformatics, 35 (2). pp. 352-360.

Lai, Xin, Eberhardt, Martin, Schmitz, Ulf, and Vera, Julio (2019) Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer. Nucleic Acids Research, 47 (15). pp. 7753-7766.

Monteuuis, Geoffray, Wong, Justin J.L., Bailey, Charles G., Schmitz, Ulf, and Rasko, John E.J. (2019) The changing paradigm of intron retention: regulation, ramifications and recipes. Nucleic Acids Research, 47 (22). pp. 11497-11513.

Amirkhah, Raheleh, Naderi-Meshkin, Hojjat, Shah, Jaynish S., Dunne, Philip D., and Schmitz, Ulf (2019) The intricate interplay between epigenetic events, alternative splicing and noncoding RNA deregulation in colorectal cancer. Cells, 8 (8). 929.

Vanichkina, Darya P., Schmitz, Ulf, Wong, Justin J.-L., and Rasko, John E.J. (2018) Challenges in defining the role of intron retention in normal biology and disease. Seminars in Cell and Developmental Biology, 75. pp. 40-49.

Rajasekhar, Magha, Schmitz, Ulf, Flamant, Stephane, Wong, Justin J.-L., Bailey, Charles G., Ritchie, Willian, Holst, Jeff, and Rasko, John E.J. (2018) Identifying microRNA determinants of human myelopoiesis. Scientific Reports, 8. 7264.

Lai, Xin, Gupta, Shailendra K., Schmitz, Ulf, Marquardt, Stephan, Knoll, Susanne, Spitschak, Alf, Wolkenhauer, Olaf, Pützer, Brigitte M., and Vera, Julio (2018) MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance. Theranostics, 8 (4). pp. 1106-1120.

Marshall, A.D., Bailey, C.G., Champ, K., Vellozzi, M., O'Young, P., Metierre, C., Feng, Y., Thoeng, A., Richards, A.M., Schmitz, U., Biro, M., Jayasinghe, R., Ding, L., Anderson, L., Mardis, E.R., and Rasko, J.E.J. (2017) CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic. Oncogene, 36. pp. 4100-4110.

Amirkhah, Raheleh, Meshkin, Hojjat Naderi, Farazmand, Ali, Rasko, John E.J., and Schmitz, Ulf (2017) Computational and experimental identification of tissue-specific MicroRNA targets. In: Dalmay, Tamas, (ed.) MicroRNA Detection and Target Identification: methods and protocols. Methods in Molecular Biology, 1580 . Humana Press Inc., New York, NY, USA, pp. 127-147.

Schmitz, Ulf, Pinello, Natalia, Jia, Fangzhi, Alasmari, Sultan, Ritchie, William, Keightley, Maria-Cristina, Shini, Shaniko, Lieschke, Graham J., Wong, Justin J-L., and Rasko, John E.J. (2017) Intron retention enhances gene regulatory complexity in vertebrates. Genome Biology, 18. 216.

Khan, Faiz M., Marquardt, Stephan, Gupta, Shailendra K., Knoll, Susanne, Schmitz, Ulf, Spitschak, Alf, Engelmann, David, Vera, Julio, Wolkenhauer, Olaf, and Pützer, Brigitte M. (2017) Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures. Nature Communications, 8. 198.

Sadeghi, Mehdi, Ranjbar, Bijan, Ganjalikhany, Mohamad Reza, Khan, Faiz M., Schmitz, Ulf, Wolkenhauer, Olaf, and Gupta, Shailendra K. (2016) MicroRNA and transcription factor gene regulatory network analysis reveals key regulatory elements associated with prostate cancer progression. PLoS ONE, 11 (12). e0168760.

Gupta, Shailendra K., Jaitly, Tanushree, Schmitz, Ulf, Schuler, Gerold, Wolkenhauer, Olaf, and Vera, Julio (2016) Personalized cancer immunotherapy using Systems Medicine approaches. Briefings in Bioinformatics, 17 (3). pp. 453-467.

Wong, Justin J.-L., Au, Amy Y.M., Gao, Dada, Pinello, Natalia, Kwok, Chau-To, Thoeng, Annora, Lau, Katherine A., Gordon, Jane E.A., Schmitz, Ulf, Feng, Yue, Nguyen, Trung V., Middleton, Robert, Bailey, Charles G., Holst, Jeff, Rasko, John E.J., and Ritchie, William (2016) RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever. Nucleic Acids Research, 44 (6). pp. 2888-2897.

Amirkhah, Raheleh, Farazmand, Ali, Wolkenhauer, Olaf, and Schmitz, Ulf (2016) RNA systems biology for cancer: From diagnosis to therapy. In: Scmitz, U., and Wolkenhauer, O., (eds.) Systems Medicine. Methods in Molecular Biology, 1386 . Springer, New York, NY, USA, pp. 305-330.

Schmitz, Ulf, Naderi-Meshkin, Hojjat, Gupta, Shailendra K., Wolkenhauer, Olaf, and Vera, Julio (2016) The RNA world in the 21st century-a systems approach to finding non-coding keys to clinical questions. Briefings in Bioinformatics, 17 (3). pp. 380-392.

Schmitz, Ulf, and Wolkenhauer, Olaf (2016) Systems medicine. Methods in Molecular Biology, 1386 . Springer, New York, USA.

Wolfien, Markus, Rimmbach, Christian, Schmitz, Ulf, Jung, Julia Jeannine, Krebs, Stefan, Steinhoff, Gustav, David, Robert, and Wolkenhauer, Olaf (2016) TRAPLINE: A standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation. BMC Bioinformatics, 17. 21.

Edwards, Christopher R., Ritchie, William, Wong, Justin J-L., Schmitz, Ulf, Middleton, Robert, An, Xiuli, Mohandas, Narla, Rasko, John E.J., and Blobel, Gerd A. (2016) A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages. Blood, 127 (17). e24-e34.

Amirkhah, Raheleh, Schmitz, Ulf, Linnebacher, Michael, Wolkenhauer, Olaf, and Farazmand, Ali (2015) MicroRNA-mRNA interactions in colorectal cancer and their role in tumor progression. Genes, Chromosomes and Cancer, 54 (3). pp. 129-141.

Amirkhah, Raheleh, Farazmand, Ali, Gupta, Shailendra K., Ahmadi, Hamed, Wolkenhauer, Olaf, and Schmitz, Ulf (2015) Naïve Bayes classifier predicts functional microRNA target interactions in colorectal cancer. Molecular BioSystems, 11. pp. 2126-2134.

Amirkhah, R., Farazmand, A., Irfan-Maqsood, M., Wolkenhauer, O., and Schmitz, U. (2015) The role of microRNAs in the resistance to colorectal cancer treatments. Cellular and Molecular Biology, 61 (6). pp. 17-23.

Schmitz, Ulf, Lai, Xin, Winter, Felix, Wolkenhauer, Olaf, Vera, Julio, and Gupta, Shailendra (2014) Cooperative gene regulation by microRNA pairs and their identification using a computational workflow. Nucleic Acids Research, 42 (12). pp. 7539-7552.

Khan, Faiz M., Schmitz, Ulf, Nikolov, Svetoslav, Engelmann, David, Pützer, Brigitte M., Wolkenhauer, Olaf, and Vera, Julio (2014) Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic. Biochimica et Biophysica Acta. Protein Structure and Molecular Enzymology, 1844 (1). pp. 289-298.

Hoffrogge, Raimund, Beyer, Susanne, Hübner, Rayk, Mikkat, Stefan, Mix, Eilhard, Scharf, Christian, Schmitz, Ulf, Pauleweit, Stefan, Berth, Matthias, Zubrzycki, Igor Z., Christoph, Hilmar, Pahnke, Jens, Wolkenhauer, Olaf, Uhrmacher, Adelinde, Völker, Uwe, and Rolfs, Arndt (2007) 2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells. Proteomics, 7 (1). pp. 33-46.

This list was generated on Mon Apr 22 17:34:48 2024 AEST.