Intron retention: importance, challenges, and opportunities
Wong, Justin J.L., and Schmitz, Ulf (2022) Intron retention: importance, challenges, and opportunities. Trends in Genetics, 38 (8). pp. 789-792.
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Abstract
Recent landmark discoveries have underpinned the physiological importance of intron retention (IR) across multiple domains of life and revealed an unexpected breath of functions in a large variety of biological processes. Despite significant progress in the field, some challenges remain. Once solved, opportunities will arise for discovering more functions of IR.
| Item ID: | 75294 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 1362-4555 |
| Keywords: | alternative splicing, epi-transcriptomics, intron retaining transcripts, RNA processing, splicing regulation |
| Copyright Information: | © 2022 Elsevier Ltd. All rights reserved. |
| Funders: | National Health and Medical Research Council (NHMRC) |
| Projects and Grants: | NHMRC 1128175, NHMRC 1158998, NHMRC 2010647, NHMRC 1196405 |
| Date Deposited: | 17 Jul 2022 23:13 |
| FoR Codes: | 31 BIOLOGICAL SCIENCES > 3105 Genetics > 310505 Gene expression (incl. microarray and other genome-wide approaches) @ 100% |
| SEO Codes: | 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280102 Expanding knowledge in the biological sciences @ 100% |
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