Intron retention: importance, challenges, and opportunities

Wong, Justin J.L., and Schmitz, Ulf (2022) Intron retention: importance, challenges, and opportunities. Trends in Genetics, 38 (8). pp. 789-792.

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Abstract

Recent landmark discoveries have underpinned the physiological importance of intron retention (IR) across multiple domains of life and revealed an unexpected breath of functions in a large variety of biological processes. Despite significant progress in the field, some challenges remain. Once solved, opportunities will arise for discovering more functions of IR.

Item ID: 75294
Item Type: Article (Research - C1)
ISSN: 1362-4555
Keywords: alternative splicing, epi-transcriptomics, intron retaining transcripts, RNA processing, splicing regulation
Copyright Information: © 2022 Elsevier Ltd. All rights reserved.
Funders: National Health and Medical Research Council (NHMRC)
Projects and Grants: NHMRC 1128175, NHMRC 1158998, NHMRC 2010647, NHMRC 1196405
Date Deposited: 17 Jul 2022 23:13
FoR Codes: 31 BIOLOGICAL SCIENCES > 3105 Genetics > 310505 Gene expression (incl. microarray and other genome-wide approaches) @ 100%
SEO Codes: 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280102 Expanding knowledge in the biological sciences @ 100%
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