Peck, Yoshimi, Pickering, Darren, Mobli, Mehdi, Liddell, Michael J., Wilson, David T, Ruscher, Roland, Ryan, Stephanie, Buitrago, Geraldine, McHugh, Connor, Love, Nicholas C., Pinlac, Theresa, Haertlein, Michael, Kron, Michael A., Loukas, Alex, and Daly, Norelle L. (2024) Solution structure of the N-terminal extension domain of a Schistosoma japonicum asparaginyl-tRNA synthetase. Journal of Biomolecular Structure and Dynamics. (In Press)

Langdon, Kane, Buitrago, Geraldine, Pickering, Darren, Giacomin, Paul, Loukas, Alex, and Haleagrahara, Nagaraja (2022) Na-AIP-1 secreted by human hookworms suppresses collagen-induced arthritis. Inflammopharmacology, 30 (2). pp. 527-535.

Ryan, Stephanie M., Ruscher, Roland, Johnston, Wayne A., Pickering, Darren A., Kennedy, Malcolm W., Smith, Brian O., Jones, Linda, Buitrago, Geraldine, Field, Matt A., Esterman, Adrian J., McHugh, Connor P., Browne, Daniel J., Cooper, Martha M., Ryan, Rachael Y.M., Doolan, Denise L., Engwerda, Christian R., Miles, Kim, Mitreva, Makedonka, Croese, John, Rahman, Tony, Alexandrov, Kirill, Giacomin, Paul R., and Loukas, Alex (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119 (36). e2202795119.

Cobos, Claudia, Bansal, Paramjit S., Wilson, David T., Jones, Linda, Zhao, Guangzu, Field, Matthew A., Eichenberger, Ramon M., Pickering, Darren A., Ryan, Rachael Y.M., Ratnatunga, Champa N., Miles, John J., Ruscher, Roland, Giacomin, Paul R., Navarro, Severine, Loukas, Alex, and Daly, Norelle L. (2022) Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells. Frontiers in Medicine, 9. 934852.

Phumrattanaprapin, Wuttipong, Pearson, Mark, Pickering, Darren, Tedla, Bemnet, Smout, Michael, Chaiyadet, Sujittra, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2021) Monoclonal antibodies targeting an opisthorchis viverrini extracellular vesicle tetraspanin protect hamsters against challenge infection. Vaccines, 9 (7). 740.

Buitrago, Geraldine, Pickering, Darren, Ruscher, Roland, Cobos Caceres, Claudia, Jones, Linda, Cooper, Martha, Van Waardenberg, Ashley, Ryan, Stephanie, Miles, Kim, Field, Matthew, Dredge, Keith, Daly, Norelle L., Giacomin, Paul R., and Loukas, Alex (2021) A netrin domain-containing protein secreted by the human hookworm Necator americanus protects against CD4 T cell transfer colitis. Translational Research, 232. pp. 88-102.

Kifle, Desalegn Woldeyohannes, Pearson, Mark S., Becker, Luke, Pickering, Darren, Loukas, Alex, and Sotillo, Javier (2020) Proteomic analysis of two populations of Schistosoma mansoni-derived extracellular vesicles: 15k pellet and 120k pellet vesicles. Molecular and Biochemical Parasitology, 236. 111264.

Mekonnen, Gebeyaw G., Tedla, Bemnet A., Pickering, Darren, Becker, Luke, Wang, Lei, Zhan, Bin, Bottazzi, Maria Elena, Loukas, Alex, Sotillo, Javier, and Pearson, Mark S. (2020) Schistosoma haematobium extracellular vesicle proteins confer protection in a heterologous model of schistosomiasis. Vaccines, 8 (3). 416.

Tedla, Bemnet, Pickering, Darren, Becker, Luke, Loukas, Alex, and Pearson, Mark S. (2020) Vaccination with Schistosoma mansoni cholinesterases reduces the parasite burden and egg viability in a mouse model of Schistosomiasis. Vaccines, 8 (2). 162.

Tedla, Bemnet A., Sotillo, Javier, Pickering, Darren, Eichenberger, Ramon M., Ryan, Stephanie, Becker, Luke, Loukas, Alex, and Pearson, Mark S. (2019) Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signaling and drug detoxification and are essential for parasite survival. PLoS Pathogens, 15 (12). e1008213.

Sundaraneedi, Madhu K., Tedla, Bemnet A., Eichenberger, Ramon M., Becker, Luke, Pickering, Darren, Smout, Michael J., Rajan, Siji, Wangchuk, Phurpa, Keene, F. Richard, Loukas, Alex, Collins, J. Grant, and Pearson, Mark S. (2017) Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases. PLoS Neglected Tropical Diseases, 11 (12). e0006134.

Ferreira, Ivana B., Pickering, Darren A., Troy, Sally, Croese, John, Loukas, Alex, and Navarro, Severine (2017) Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis. Clinical & Translational Immunology, 6. e157.

Wangchuk, Phurpa, Pearson, Mark S., Giacomin, Paul R., Becker, Luke, Sotillo, Javier, Pickering, Darren, Smout, Michael J., and Loukas, Alex (2016) Compounds derived from the Bhutanese daisy, Ajania nubigena, demonstrate dual anthelmintic activity against Schistosoma mansoni and Trichuris muris. PLOS Neglected Tropical Diseases, 10 (8). e0004908. pp. 1-18.

Sotillo, Javier, Pearson, Mark, Potriquet, Jeremy, Becker, Luke, Pickering, Darren, Mulvenna, Jason, and Loukas, Alex (2016) Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates. International Journal for Parasitology, 46 (1). pp. 1-5.

Navarro, Severine, Pickering, Darren A., Ferreira, Ivana B., Jones, Linda, Ryan, Stephanie, Troy, Sally, Leech, Andrew , Hotez, Peter J., Zhan, Bin, Laha, Thewarach, Prentice, Roger, Sparwasser, Tim, Croese, John, Engwerda, Christian R., Upham, John W., Julia, Valerie, Giacomin, Paul R., and Loukas, Alex (2016) Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine, 8 (362). 362ra143.

Tribolet, Leon, Cantacessi, Cinzia, Pickering, Darren, Navarro, Severine, Doolan, Denise, Trieu, Angela, Fei, Huang, Chao, Yang, Hofmann, Andreas, Gasser, Robin, Giacomin, Paul, and Loukas, Alex (2015) Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling. Journal of Infectious Diseases, 211 (3). pp. 416-425.

Fuaad, Abdullah A.H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzho, Loukas, Alex C., Skwarczynski, Mariusz, and Toth, Istvan (2015) Lipopeptide nanoparticles: development of vaccines against hookworm parasite. ChemMedChem, 10 (10). pp. 1647-1654.

Ahmad Fuaad, Abdullah A.H., Roubille, Romain, Pearson, Mark S., Pickering, Darren A., Loukas, Alex C., Skwarczynski, Mariusz, and Toth, Istvan (2015) The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni. Bioorganic & Medicinal Chemistry, 23. pp. 1307-1312.

Sotillo, Javier, Sanchez-Flores, Alejandro, Cantacessi, Cinzia, Harcus, Yvonne, Pickering, Darren, Bouchery, Tiffany, Camberis, Mali, Tang, Shiau-Choot, Giacomin, Paul, Mulvenna, Jason, Mitreva, Makedonka, Berriman, Matthew, LeGros, Graham, Maizels, Rick M., and Loukas, Alex (2014) Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis. Molecular and Cellular Proteomics, 13 (10). pp. 2736-2751.

Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J., and Mulvenna, Jason (2014) Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10). pp. 7151-7163.

Pearson, Mark S., Pickering, Darren, Ranjit, Najju, and Loukas, Alex (2013) Hookworm MEP-1 metalloproteases. In: Rawlings, Neil D., and Salvesen, Guy, (eds.) Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes, 1 . Elsevier, Amsterdam, The Netherlands, pp. 647-649.

Cantacessi, Cinzia, Hofmann, Andreas, Pickering, Darren, Navarro, Severine, Mitreva, Makedonka, and Loukas, Alex (2013) TIMPs of parasitic helminths: a large-scale analysis of high-throughput sequence datasets. Parasites & Vectors, 6 (1). 156. pp. 1-11.

Loukas, A., Ranjit, N., Pickering, D.A., and Pearson, M.S. (2012) Blood-feeding human hookworm proteases. In: Dunn, Ben, (ed.) Proteinases as Drug Targets. Royal Society of Chemistry, Cambridge, UK, pp. 186-198.

Pearson, Mark S., Pickering, Darren A., McSorley, Henry J., Bethony, Jeffrey M., Tribolet, Leon, Dougall, Annette M., Hotez, Peter J., and Loukas, Alex (2012) Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Neglected Tropical Diseases, 6 (3). e1564. pp. 1-10.

Willis, Charlene, Wang, Conan K., Osman, Asiah, Simon, Anne, Pickering, Darren, Mulvenna, Jason, Riboldi-Tunicliffe, Alan, Jones, Malcolm K., Loukas, Alex, and Hoffman, Andreas (2011) Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm. PLoS ONE, 6 (10). e25369. pp. 1-10.

Pearson, Mark S., Pickering, Darren A., Tribolet, Leon, Cooper, Leanne, Mulvenna, Jason, Oliveira, Luciana M., Bethony, Jeffrey M., Hotez, Peter J., and Loukas, Alex (2010) Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm Infection and schistosomiasis. Journal of Infectious Diseases, 201 (10). pp. 1561-1569.

Pearson, Mark S., Bethony, Jeffrey M., Pickering, Darren A., de Oliveira, Luciana M., Jariwala, Amar, Santiago, Helton, Miles, Aaron P., Zhan, Bin, Jiang, Desheng, Ranjit, Najju, Mulvenna, Jason, Tribolet, Leon, Plieskatt, Jordan, Smith, Tracey, Bottazzi, Maria Elena, Jones, Kathryn, Keegan, Brian, Hotez, Peter J., and Loukas, Alex (2009) An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB Journal, 23 (9). pp. 3009-3017.