Genetic characterization of archived bunyaviruses and their potential for emergence in Australia
Huang, Bixing, Firth, Cadhla, Watterson, Daniel, Allcock, Richard, Colmant, Agathe M.G., Hobson-Peters, Jody, Kirkland, Peter, Hewitson, Glen, Mcmahon, Jamie, Hall-Mendelin, Sonja, van den Hurk, Andrew F., and Warrilow, David (2016) Genetic characterization of archived bunyaviruses and their potential for emergence in Australia. Emerging Infectious Diseases, 22 (5). pp. 833-840.
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Abstract
To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae. Gan Gan and Trubanaman viruses almost perfectly matched 2 recently isolated, purportedly novel viruses, Salt Ash and Murrumbidgee viruses, respectively. Kowanyama and Yacaaba viruses were identified as being related to members of a large clade containing pathogenic viruses. Taggert virus was confirmed as being a nairovirus; several viruses of this genus are pathogenic to humans. The genetic relationships and historical experimental infections in mice reveal the potential for these viruses to lead to disease emergence.
| Item ID: | 59902 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 1080-6059 |
| Funders: | Queensland Health |
| Date Deposited: | 16 Sep 2019 01:28 |
| FoR Codes: | 31 BIOLOGICAL SCIENCES > 3105 Genetics > 310509 Genomics @ 50% 31 BIOLOGICAL SCIENCES > 3107 Microbiology > 310706 Virology @ 50% |
| SEO Codes: | 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100% |
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