Exploring the relationships between mutation rates, life history, genome size, environment, and species richness in flowering plants

Bromham, Lindell, Hua, Xia, Lanfear, Robert, and Cowman, Peter F. (2015) Exploring the relationships between mutation rates, life history, genome size, environment, and species richness in flowering plants. American Naturalist, 185 (4). pp. 507-524.

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Abstract

A new view is emerging of the interplay between mutation at the genomic level, substitution at the population level, and diversification at the lineage level. Many studies have suggested that rate of molecular evolution is linked to rate of diversification, but few have evaluated competing hypotheses. By analyzing sequences from 130 families of angiosperms, we show that variation in the synonymous substitution rate is correlated among genes from the mitochondrial, chloroplast, and nuclear genomes and linked to differences in traits among families (average height and genome size). Within each genome, synonymous rates are correlated to nonsynonymous substitution rates, suggesting that increasing the mutation rate results in a faster rate of genome evolution. Substitution rates are correlated with species richness in protein-coding sequences from the chloroplast and nuclear genomes. These data suggest that species traits contribute to lineage-specific differences in the mutation rate that drive both synonymous and nonsynonymous rates of change across all three genomes, which in turn contribute to greater rates of divergence between populations, generating higher rates of diversification. These observations link mutation in individuals to population-level processes and to patterns of lineage divergence.

Item ID: 49190
Item Type: Article (Refereed Research - C1)
Keywords: comparative, phylogeny, substitution rates, angiosperm, diversification rate.
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Authors may deposit either the published PDF of their article or the final accepted version of the manuscript after peer review (but not proofs of the article) in a non-commercial repository where it can be made freely available no sooner than twelve (12) months after publication of the article in the journal. See: http://www.journals.uchicago.edu/open

ISSN: 1537-5323
Date Deposited: 07 Jun 2017 07:30
FoR Codes: 06 BIOLOGICAL SCIENCES > 0603 Evolutionary Biology > 060309 Phylogeny and Comparative Analysis @ 30%
06 BIOLOGICAL SCIENCES > 0604 Genetics > 060409 Molecular Evolution @ 40%
06 BIOLOGICAL SCIENCES > 0607 Plant Biology > 060702 Plant Cell and Molecular Biology @ 30%
SEO Codes: 96 ENVIRONMENT > 9608 Flora, Fauna and Biodiversity > 960805 Flora, Fauna and Biodiversity at Regional or Larger Scales @ 50%
97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 50%
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