Publications by: Paul F. Alewood

Also publishes as (Paul Alewood, P.F. Alewood)

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Number of items: 34.

Moral-Sanz, Javier, Fernandez-Rojo, Manuel A., Colmenarejo, Gonzalo, Kurdyukov, Sergey, Brust, Andreas, Ragnarsson, Lotten, Andersson, Asa, Vila, Sabela F., Cabezas-Sainz, Pablo, Wilhelm, Patrick, Vela-Sebastian, Ana, Fernandez-Carrasco, Isabel, Chin, Yanni K.Y., Lopez-Mancheno, Yaiza, Smallwood, Taylor B., Clark, Richard J., Fry, Bryan G., King, Glenn F., Ramm, Grant A., Alewood, Paul F., Lewis, Richard J., Mulvenna, Jason P., Boyle, Glen M., Sanchez, Laura E., Neely, G. Gregory, Miles, John J., and Ikonomopoulou, Maria P. (2022) The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAF(V600E). British Journal of Pharmacology, 179 (20). pp. 4878-4896.

Moral-Sanz, Javier, Fernandez-Rojo, Manuel A., Potriquet, Jeremy, Mukhopadhyay, Pamela, Brust, Andreas, Wilhelm, Patrick, Smallwood, Taylor B., Clark, Richard J., Fry, Bryan G., Alewood, Paul F., Waddell, Nicola, Miles, John J., Mulvenna, Jason P., and Ikonomopoulou, Maria P. (2021) ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations. Toxins, 13 (2). 146.

Herzig, Volker, Sunagar, Kartik, Wilson, David T.R., Pineda, Sandy S., Israel, Mathilde R., Dutertre, Sebastien, McFarland, Brianna Sollod, Undheim, Eivind A.B., Hodgson, Wayne C., Alewood, Paul F., Lewis, Richard J., Bosmans, Frank, Vetter, Irina, King, Glenn F., and Fry, Bryan G. (2020) Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators. Proceedings of the National Academy of Sciences of the United States of America, 117 (40). pp. 24920-24928.

Reeks, Timothy, Jones, Alun, Brust, Andreas, Sridharan, Sindhuja, Corcilius, Leo, Wilkinson, Brendan L., Thaysen-Andersen, Morten, Payne, Richard J., Kini, R. Manjunatha, Daly, Norelle L., and Alewood, Paul F. (2015) A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus. Angewandte Chemie International Edition, 54 (16). pp. 4828-4831.

Mueller, Alexander, Starobova, Hana, Inserra, Marco C., Jin, Ai-Hua, Deuis, Jennifer R., Dutertre, Sébastien, Lewis, Richard J., Alewood, Paul F., Daly, Norelle L., and Vetter, Irina (2015) α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology, 94 (2). pp. 155-163.

Vink, Simone, Daly, Norelle, Steen, Natalie, Craik, David J., and Alewood, Paul F. (2014) Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90. pp. 308-317.

Berecki, G., Daly, N.L., Huang, Y.H., Vink, S., Craik, D.J., Alewood, P.F., and Adams, D.J. (2014) Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels. British Journal of Pharmacology, 171 (13). pp. 3313-3327.

Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric, and Nitabach, Michael N. (2014) A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Current Biology, 24 (5). pp. 473-483.

Inserra, Marco C., Kompella, Shiva N., Vetter, Irina, Brust, Andreas, Daly, Norelle L., Cuny, Hartmut, Craik, David J., Alewood, Paul F., Adams, David J., and Lewis, Richard J. (2013) Isolation and characterization of alpha-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology, 86 (6). pp. 791-799.

Franco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams, David J., and Marí, Frank (2012) RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology, 83 (3). pp. 419-426.

Dekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J., and Alewood, Paul F. (2011) α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40). pp. 15866-15869.

de Araujo, Aline Dantas, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J., and Alewood, Paul F. (2011) Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie International Edition, 50 (29). pp. 6527-6529.

Morales, Rodrigo A.V., Daly, Norelle L., Vetter, Irina, Mobli, Mehdi, Napier, Ian A., Craik, David J., Lewis, Richard J., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., and Durek, Thomas (2010) Chemical synthesis and structure of the prokineticin Bv8. ChemBioChem, 11 (13). pp. 1882-1888.

Luo, Sulan, Akondi, Kalyana Bharati, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Christensen, Sean, Dowell, Cheryl, Daly, Norelle, Craik, David, Wang, Ching-I., Lewis, Richard J., Alewood, Paul F., and McIntosh, J. Michael (2010) Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the α3β2 nicotinic receptor. Journal of Biological Chemistry, 285 (16). pp. 12355-12366.

Muttenthaler, Markus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J., and Alewood, Paul F. (2010) Solving the α-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society, 132 (10). pp. 3514-3522.

Berecki, G., Motin, L.H., Haythornthwaite, A., Vink, S., Bansal, P., Drinkwater, R., Wang, C.I., Moretta, M., Lewis, R.J., Alewood, P.F., Christie, M.J., and Adams, D.J. (2010) Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels. Molecular Pharmacology, 77 (2). pp. 139-148.

Pages, Guilhem, Torres, Allan M., Ju, Pengchu, Bansal, Paramjit, Alewood, Paul F., Kuchel, Philip W., and Vandenberg, Jamie L. (2009) Structure of the pore-helix of the hERG K(+) channel. European Biophysics Journal, 39 (1). pp. 111-120.

Millard, Emma L., Nevin, Simon T., Loughnan, Marlon L., Nicke, Annette, Clark, Richard J., Alewood, Paul F., Lewis, Richard J., Adams, David J., Craik, David J., and Daly, Norelle L. (2009) Inhibition of neuronal nicotinic acetylcholine receptor subtypes by α-Conotoxin GID and analogues. Journal of Biological Chemistry, 284 (8). pp. 4944-4951.

Brust, Andreas, Palant, Elka, Croker, Daniel E., Colless, Barbara, Drinkwater, Roger, Patterson, Brad, Schroeder, Christina I., Wilson, David, Nielsen, Carsten K., Smith, Maree T., Alewood, Dianne, Alewood, Paul F., and Lewis, Richard J. (2009) chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain. Journal of Medicinal Chemistry, 52 (22). pp. 6991-7002.

Jin, Ai-Hua, Daly, Norelle L., Nevin, Simon T., Wang, Ching-I A., Dutertre, Sebastien, Lewis, Richard J., Adams, David J., Craik, David J., and Alewood, Paul F. (2008) Molecular engineering of conotoxins: the importance of loop size to α-conotoxin structure and function. Journal of Medicinal Chemistry, 51 (18). pp. 5575-5584.

Imperial, Julita S., Chen, Ping, Sporning, Annett, Terlau, Heinrich, Daly, Norelle L., Craik, David J., Alewood, Paul F., and Olivera, Baldomero M. (2008) Tyrosine-rich conopeptides affect voltage-gated K+ channels. Journal of Biological Chemistry, 283 (34). pp. 23026-23032.

Dutertre, Sebastien, Croker, Daniel, Daly, Norelle L., Andersson, Asa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles, and Lewis, Richard J. (2008) Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides. Journal of Biological Chemistry, 283 (11). pp. 7100-7108.

Wilson, David, and Alewood, Paul F. (2006) Taxonomy of Australian funnel-web spiders using rp-HPLC/ESI-MS profiling techniques. Toxicon, 47 (6). pp. 614-627.

Brust, A., Alewood, D., Colless, B, Palant, E, Patterson, B, Wilson, D, Watson, F, Schroeder , C.I., Alewood, P.F., and Lewis, R.J. (2006) conopeptide to drug: the development, structure and activity correlation of Xen2174. Journal of Peptide Science, 12 (Supplement 1). M418. p. 516.

Wen, Suping, Wilson, David T.R., Kuruppu, Sanjaya, Korsinczky, Michael L.J., Hedrick, Joseph, Pang, Ling, Szeto, Tim, Hodgson, Wayne C., Alewood, Paul F., and Nicholson, Graham M. (2005) Discovery of an MIT-like atracotoxin family: spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins. Peptides, 26 (12). pp. 2412-2426.

Wilson, David, and Alewood, Paul (2004) Australian Funnel-Web Spider venom analyzed with on-line RP-HPLC techniques. In: Aguilar, M.-I., (ed.) HPLC of peptides and proteins: methods and protocols. Methods in Molecular Biology, 251 . Humana Press, Totowa, NJ, pp. 307-322.

Sharpe, Iain A., Thomas, Linda, Loughnan, Marion, Motin, Leonid, Palant, Elka, Croker, Daniel E., Alewood, Dianne, Chen, Songhai, Graham, Robert M., Alewood, Paul F., Adams, David J., and Lewis, Richard J. (2003) Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. Journal of Biological Chemistry, 278 (36). pp. 34451-34457.

Nielsen, Katherine J., Watson, Michael, Adams, David J., Hammarstrom, Anna K., Gage, Peter W., Hill, Justine M., Craik, David J., Thomas, Linda, Adams, Denise, Alewood, Paul F., and Lewis, Richard J. (2002) Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. Journal of Biological Chemistry, 277 (30). pp. 27247-27255.

Rosengren, K. Johan, Wilson, David, Daly, Norelle L., Alewood, Paul F., and Craik, David J. (2002) Solution Structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche infensa sp. that contains a cystine-knot motif within its four disulfide bonds. Biochemistry, 41 (10). pp. 3294-3301.

Graudins, A., Wilson, D., Alewood, P.F., Broady, K.W., and Nicholson, G.M. (2002) Cross-reactivity of Sydney funnel-web spider antivenom: neutralization of the in vitro toxicity of other Australian funnel-web (Atrax and Hadronyche) spider venoms. Toxicon, 40 (3). pp. 259-266.

Wang, Xiu-Hong, Connor, Mark, Wilson, David, Wilson, Harry I., Nicholson, Graham M., Smith, Ross, Shaw, Denis, Mackay, Joel P., Alewood, Paul, Christie, Macdonald J., and King, Glenn F. (2001) Discovery and structure of a potent and highly specific blocker of insect calcium channels. Journal of Biological Chemistry, 276 (43). pp. 40306-40312.

Sharpe, Iain A., Gehrmann, John, Loughnan, Marion L., Thomas, Linda, Adams, Denise A., Atkins, Ann, Palant, Elka, Alewood, Paul F., Craik, David J., Adams, David J, and Lewis, Richard J. (2001) Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nature neuroscience, 4 (9). pp. 902-907.

Lewis, Richard J., Nielsen, Katherine J., Craik, David J., Loughnan, Marion L., Adams, Denise A., Sharpe, Iain A., Luchian, Tudor, Adams, David J., Bond, Trudy, Thomas, Linda, Jones, Alun, Matheson, Jodi-Lea, Drinkwater, Roger, Andrews, Peter R., and Alewood, Paul F. (2000) Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. Journal of Biological Chemistry, 275 (45). pp. 35335-35344.

Alewood, Paul, Alewood, Dianne, Miranda, Les, Love, Stephen, Meutermans, Wim, and Wilson, David (1997) Rapid in situ neutralization protocols for Boc and Fmoc solid-phase chemistries. Methods in Enzymology, 289. pp. 14-29.

This list was generated on Thu Mar 28 13:46:42 2024 AEST.