Marine algal compounds as novel therapeutics for food allergy
Pratap, Kunal (2022) Marine algal compounds as novel therapeutics for food allergy. PhD thesis, James Cook University.
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Abstract
Kunal Pratap investigated the therapeutic potential of marine algal-based compounds for food allergy. He demonstrated the allergy-suppressing properties of purified polysaccharides from green algae and highlighted the crucial role of gut microbiome in modulating allergic diseases using in vivo models.
| Item ID: | 78595 |
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| Item Type: | Thesis (PhD) |
| Keywords: | algae, allergen, astaxanthin, carotenoid, food allergens, food allergy, gut microbiome, immunotherapy, legumin, macadamia allergy, macadamia nut, medicinal plants, microbiota, mouse model, natural compounds, polysaccharides, probiotics, tree nut allergy, ulvan, vicilin |
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| Copyright Information: | Copyright © 2022 Kunal Pratap. |
| Additional Information: | Three publications arising from this thesis are stored in ResearchOnline@JCU, at the time of processing. Please see the Related URLs. The publications are: [Chapter 1] Pratap, Kunal, Taki, Aya C., Johnston, Elecia B., Lopata, Andreas L., and Kamath, Sandip D. (2020) A comprehensive review on natural bioactive compounds and probiotics as potential therapeutics in food allergy treatment. Frontiers in Immunology, 11. 996. [Chapter 4] Pratap, Kunal, Majzoub, Marwan E., Taki, Aya C., Miranda Hernandez, Socorro, Magnusson, Marie, Glasson, Christopher, de Nys, Rocky, Thomas, Torsten, Lopata, Andreas L., and Kamath, Sandip D. (2022) The Algal Polysaccharide Ulvan and Carotenoid Astaxanthin Both Positively Modulate Gut Microbiota in Mice. Foods, 11 (4). 565. [Chapter 5] Kabasser, Stefan, Pratap, Kunal, Kamath, Sandip, Taki, Aya, Dang, Thanh, Koplin, Jennifer, Perrett, Kirsten, Hummel, Karin, Radauer, Christian, Breiteneder, Heimo, Lopata, Andreas L., and Bublin, Merima (2022) Identification of vicilin, legumin and antimicrobial peptide 2a as macadamia nut allergens. Food Chemistry, 370. 131028. |
| Date Deposited: | 24 Apr 2023 02:58 |
| FoR Codes: | 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320401 Allergy @ 40% 34 CHEMICAL SCIENCES > 3404 Medicinal and biomolecular chemistry > 340499 Medicinal and biomolecular chemistry not elsewhere classified @ 30% 31 BIOLOGICAL SCIENCES > 3101 Biochemistry and cell biology > 310101 Analytical biochemistry @ 30% |
| SEO Codes: | 20 HEALTH > 2004 Public health (excl. specific population health) > 200405 Food safety @ 40% 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 30% 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280103 Expanding knowledge in the biomedical and clinical sciences @ 30% |
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