Schistosoma mansoni extracellular vesicles: immunobiology and vaccine efficacy
Kifle, Desalegn Woldeyohannes (2020) Schistosoma mansoni extracellular vesicles: immunobiology and vaccine efficacy. PhD thesis, James Cook University.
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Abstract
Desalegn Kifle characterized the molecular composition of extracellular vesicles secreted by Schistosoma mansoni parasites. He demonstrated their role in host-parasite communication via host cell gene regulation, as well as their vaccine potential. His findings could have potential impact on our understanding of schistosome biology and the wider field of molecular parasitology.
| Item ID: | 64835 |
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| Item Type: | Thesis (PhD) |
| Keywords: | schistosomiasis, Schistosoma mansoni, extracellular vesicles, parasites, host-parasite communication, host cell gene regulation, schistosome biology, molecular parasitology, vaccine efficacy |
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| Copyright Information: | © 2020 Desalegn Woldeyohannes Kifle. |
| Additional Information: | Two publications arising from this thesis are stored in ResearchOnline@JCU, at the time of processing. Please see the Related URLs. The publications are: Kifle, Desalegn Woldeyohannes, Pearson, Mark S., Becker, Luke, Pickering, Darren, Loukas, Alex, and Sotillo, Javier (2020) Proteomic analysis of two populations of Schistosoma mansoni-derived extracellular vesicles: 15k pellet and 120k pellet vesicles. Molecular and Biochemical Parasitology, 236. 111264. Kifle, Desalegn Woldeyohannes, Sotillo, Javier, Pearson, Mark S., and Loukas, Alex (2017) Extracellular vesicles as a target for the development of anti-helminth vaccines. Emerging Topics in Life Sciences, 1 (6). pp. 659-665. |
| Date Deposited: | 26 Oct 2020 07:06 |
| FoR Codes: | 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology @ 100% |
| SEO Codes: | 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 50% 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920412 Preventive Medicine @ 50% |
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