Graphical spreadsheet tools for learning enzyme kinetics

Brown, Simon, and Simcock, David C. (2017) Graphical spreadsheet tools for learning enzyme kinetics. International Journal of Open Information Technology, 5 (8). pp. 40-45.

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Many students lack sufficient mathematical skill or confidence to be able to visualise a process just by looking at an equation. This is particularly apparent when students are working on the dynamics of enzyme action. Understanding the basic concepts of enzyme kinetics is essential to any appreciation of the chemical processes that occur in living organisms. Fortunately, learning can be enhanced by direct manipulation of the parameters while students observe the behaviour of the graphs of the functions. Spreadsheets are described that enable students to analyse the significance of the parameters at several levels, to connect concepts between levels of treatment and to use the basic expression in the analysis of their own experiments. Methods for constructing these spreadsheets in Excel and the essentials of the relevant theory are also summarised.

Item ID: 52493
Item Type: Article (Research - C1)
ISSN: 2307-8162
Keywords: dynamics; enzyme kinetics; nonlinear regression; spreadsheet
Date Deposited: 14 Feb 2018 05:08
FoR Codes: 31 BIOLOGICAL SCIENCES > 3101 Biochemistry and cell biology > 310106 Enzymes @ 40%
39 EDUCATION > 3901 Curriculum and pedagogy > 390113 Science, technology and engineering curriculum and pedagogy @ 30%
46 INFORMATION AND COMPUTING SCIENCES > 4613 Theory of computation > 461306 Numerical computation and mathematical software @ 30%
SEO Codes: 93 EDUCATION AND TRAINING > 9302 Teaching and Instruction > 930203 Teaching and Instruction Technologies @ 60%
89 INFORMATION AND COMMUNICATION SERVICES > 8902 Computer Software and Services > 890202 Application Tools and System Utilities @ 40%
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