Blake, Judith Anne (2024) Lung epithelial progenitor cell-mediated release of TGF-β regulates induction and persistence of lung CD8+ TRM cells following mucosal BCG vaccination. PhD thesis, James Cook University.

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Abstract

Doctor Judith Blake examined lung reparative processes and long-term immune memory after inhalation of mycobacterium. She reported new knowledge related to development of an efficient pulmonary vaccine against tuberculosis.

Item ID:	93250
Item Type:	Thesis (PhD)
Keywords:	TGF-β, lung health, mucosal BCG vaccination, lung epithelial progenitor, CD8+ TRM
Related URLs:	https://researchonline.jcu.edu.au/86517/
Copyright Information:	Copyright © 2024 Judith Anne Blake
Additional Information:	One publication arising from this thesis is stored in ResearchOnline@JCU, at time of processing. Please see the Related URLS. The publication is: [Chapter 2-5] Blake, Judith A., Seifert, Julia, Miranda-Hernandez, Socorro, Ruscher, Roland, Giacomin, Paul R., Doolan, Denise L., and Kupz, Andreas (2025) Distal airway epithelial progenitors mediate TGF-β release to drive lung CD8+ TRM induction following mucosal BCG vaccination. Mucosal Immunology. (In Press)
Date Deposited:	09 Aug 2026 23:57
FoR Codes:	31 BIOLOGICAL SCIENCES > 3107 Microbiology > 310702 Infectious agents @ 30% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320404 Cellular immunology @ 30% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3207 Medical microbiology > 320701 Medical bacteriology @ 40%
SEO Codes:	28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280103 Expanding knowledge in the biomedical and clinical sciences @ 100%
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