Kabdrakhmanova, Sana, Augustine, Robin, Sathian, Aiswarya, Thomas, Annu, Joseph, Tomy Muringayil, Kalarikkal, Nandakumar, Ibraeva, Zhanar, Madiyar, Beisebekov, Thomas, Sabu, Hasan, Anwarul, and Joshy, K. S. (2025) Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce. Journal of Polymer Science, 63 (24). pp. 5414-5425.

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Abstract

The purpose of the present study was to develop a nano-coating for fresh vegetables and fruits using a combination of curcumin, sesame oil, stearic acid, and dextran (CSSDNs). The anti-bacterial and nontoxic nature of nanoparticles were tested against Gram-positive bacteria (Staphylococcusaureus) and human fibroblast cells. Enhanced aqueous solubility of curcumin and its stability in the bloodstream were observed from the in vitro blood compatibility studies. The anti-cancer activity of curcumin-loaded nanoparticles was tested against SK-BR3 cells, demonstrating excellent antitumor activity. These findings indicate that the CSSDNs system can be used as an edible coating with strong antibacterial properties and as an effective means of delivering curcumin, which has proven to be successful in treating or preventing cancer.

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