Primary Intranodal Epithelioid Haemangioendothelioma in the Submandibular Region: A Case Report

Shukla, Khilan, Taheri, Touraj, Baghaie, Hooman, and Breik, Omar (2024) Primary Intranodal Epithelioid Haemangioendothelioma in the Submandibular Region: A Case Report. Indian Journal of Otolaryngology and Head and Neck Surgery, 76. pp. 3956-3961.

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Abstract

Epithelioid haemangioendothelioma (EHE) is a rare vascular tumour that primarily affects the liver, lungs and bone. It is very rarely described in the head and neck region, and is exceptionally uncommon within the submandibular region. We report a very rare case of EHE originating in a lymph node within the submandibular salivary gland of a 54-year-old female patient. The tumour was resected and the patient was regularly followed up, with no recurrence of disease at 24 months postoperatively. A review of existing literature, clinical and immunohistopathological features are discussed, which highlight the diagnostic dilemma, absence of consensus for management and appropriate surveillance method associated with EHE.

Item ID: 87480
Item Type: Article (Research - C1)
ISSN: 0973-7707
Keywords: Epithelioid haemangioendothelioma, Head and neck pathology, Head and neck surgery, Malignancy, Submandibular gland
Copyright Information: © Crown 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Date Deposited: 09 Dec 2025 01:25
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3202 Clinical sciences > 320217 Otorhinolaryngology @ 100%
SEO Codes: 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280103 Expanding knowledge in the biomedical and clinical sciences @ 100%
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