Kumari, Deepa, Prajapati, Megha, and Ravi Kant, Chhaya (2024) Highly Efficient Non-Enzymatic Electrochemical Glucose Biosensor Based on Copper Metal Organic Framework Coated on Graphite Sheet. ECS Journal of Solid State Science and Technology, 13. 047007.

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Abstract

Detection of glucose is highly informative, creating a constant demand for fabricating high-precision glucose biosensors. Metal–organic frameworks, a family of porous materials renowned for their tunability, can be an excellent choice for developing such sensors. We have developed a highly-sensitive, non-enzymatic sensor for electrochemical detection of glucose fabricated using Copper Metal–Organic Framework (Cu MOF), synthesized by a simple, room-temperature stirring method using Benzene-1,3,5-tricarboxylic acid (BTC) as ligand and Copper nitrate trihydrate as precursor. The synthesized nanostructure was characterized using Fourier transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive X-ray analytical techniques. Powder X-ray diffraction study and thermogravimetric analysis were also done. Further, Brunnauer-Emmett-Teller analysis revealed the porous nature of Cu MOF. The materials exhibited strong electro-catalytic activity for glucose oxidation as revealed from cyclic voltammetry and chronoamperometric studies done under alkaline pH conditions. The Cu MOF deposited on a conducting graphite sheet electrode displayed a significantly low detection limit of 0.019 mM through a broad detection range (1–15 mM) and a strong sensitivity of 229.4 μAmM−1 cm2. Overall, the Cu MOF/GS exhibits exceptional stability, short response time (less than 1 s), and good repeatability and reproducibility, making it a promising future material for non-enzymatic glucose detection.

Item ID:	86009
Item Type:	Article (Research - C1)
ISSN:	2162-8777
Copyright Information:	© 2024 The Electrochemical Society (“ECS”). Published on behalf of ECS by IOP Publishing Limited. All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Date Deposited:	01 Jul 2025 23:06
FoR Codes:	40 ENGINEERING > 4003 Biomedical engineering > 400399 Biomedical engineering not elsewhere classified @ 100%
SEO Codes:	24 MANUFACTURING > 2499 Other manufacturing > 249999 Other manufacturing not elsewhere classified @ 100%
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