Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies

Lane, Melissa M., Travica, Nikolaj, Gamage, Elizabeth, Marshall, Skye, Trakman, Gina L., Young, Claire, Teasdale, Scott B., Dissanayaka, Thusharika, Dawson, Samantha L., Orr, Rebecca, Jacka, Felice N., O'Neil, Adrienne, Lawrence, Mark, Baker, Phillip, Rebholz, Casey M., Du, Shutong, and Marx, Wolfgang (2024) Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies. Annual Review of Nutrition, 44. pp. 383-404.

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Abstract

Our aim was to conduct an umbrella review of evidence from meta-analyses of observational studies investigating the link between sugar-sweetened beverage consumption and human health outcomes. Using predefined evidence classification criteria, we evaluated evidence from 47 meta-analyses encompassing 22,055,269 individuals. Overall, 79% of these analyses indicated direct associations between greater sugar-sweetened beverage consumption and higher risks of adverse health outcomes. Convincing evidence (class I) supported direct associations between sugar-sweetened beverage consumption and risks of depression, cardiovascular disease, nephrolithiasis, type 2 diabetes mellitus, and higher uric acid concentrations. Highly suggestive evidence (class II) supported associations with risks of nonalcoholic fatty liver disease and dental caries. Out of the remaining 40 meta-analyses, 29 were graded as suggestive or weak in the strength of evidence (classes III and IV), and 11 showed no evidence (class V). These findings inform and provide support for population-based and public health strategies aimed at reducing sugary drink consumption for improved health.

Item ID: 85723
Item Type: Article (Research - C1)
ISSN: 1545-4312
Copyright Information: Copyright © 2024 by the author(s). This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See credit lines of images or other third-party material in this article for license information.
Date Deposited: 04 Jun 2025 00:40
FoR Codes: 32 BIOMEDICAL AND CLINICAL SCIENCES > 3210 Nutrition and dietetics > 321005 Public health nutrition @ 100%
SEO Codes: 20 HEALTH > 2004 Public health (excl. specific population health) > 200410 Nutrition @ 100%
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