Kong, Amanda Shen-Yee, Lai, Kok-Song, Lim, Swee-Hua Erin, Sivalingam, Sivakumar, Loh, Jiun-Yan, and Maran, Sathiya (2022) miRNA in Ischemic Heart Disease and Its Potential as Biomarkers: A Comprehensive Review. International Journal of Molecular Sciences, 23 (16). 9001.

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Abstract

Ischemic heart disease (IHD) constitutes the leading global cause of mortality and morbidity. Although significant progress has been achieved in the diagnosis, treatment, and prognosis of IHD, more robust diagnostic biomarkers and therapeutic interventions are still needed to circumvent the increasing incidence of IHD. MicroRNAs (miRNAs) are critical regulators of cardiovascular function and are involved in various facets of cardiovascular biology. While the knowledge of the role of miRNAs in IHD as diagnostic biomarkers has improved, research emphasis on how miRNAs can be effectively used for diagnosis and prognosis of IHD is crucial. This review provides an overview of the biology, therapeutic and diagnostic potential, as well as the caveats of using miRNAs in IHD based on existing research.

Item ID:	83353
Item Type:	Article (Research - C1)
ISSN:	1422-0067
Copyright Information:	© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Date Deposited:	06 Aug 2024 21:43
FoR Codes:	31 BIOLOGICAL SCIENCES > 3105 Genetics > 310509 Genomics @ 100%
SEO Codes:	20 HEALTH > 2099 Other health > 209999 Other health not elsewhere classified @ 100%
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