Alameri, Meera Mohamed, Kong, Amanda Shen-Yee, Aljaafari, Mariam Nasser, Al Ali, Hajer, Eid, Khadija, Al Sallagi, Maryam, Cheng, Wan-Hee, Abushelaibi, Aisha, Lim, Swee-Hua Erin, Loh, Jiun-Yan, and Lai, Kok-Song (2023) Aflatoxin Contamination: An Overview on Health Issues, Detection and Management Strategies. Toxins, 15. 246.

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Abstract

Aflatoxins (AFs) represent one of the main mycotoxins produced by Aspergillus flavus and Aspergillus parasiticus, with the most prevalent and lethal subtypes being AFB1, AFB2, AFG1, and AFG2. AFs are responsible for causing significant public health issues and economic concerns that affect consumers and farmers globally. Chronic exposure to AFs has been linked to liver cancer, oxidative stress, and fetal growth abnormalities among other health-related risks. Although there are various technologies, such as physical, chemical, and biological controls that have been employed to alleviate the toxic effects of AF, there is still no clearly elucidated universal method available to reduce AF levels in food and feed; the only mitigation is early detection of the toxin in the management of AF contamination. Numerous detection methods, including cultures, molecular techniques, immunochemical, electrochemical immunosensor, chromatographic, and spectroscopic means, are used to determine AF contamination in agricultural products. Recent research has shown that incorporating crops with higher resistance, such as sorghum, into animal feed can reduce the risk of AF contamination in milk and cheese. This review provides a current overview of the health-related risks of chronic dietary AF exposure, recent detection techniques, and management strategies to guide future researchers in developing better detection and management strategies for this toxin.

Item ID:	83259
Item Type:	Article (Research - C1)
ISSN:	2072-6651
Copyright Information:	© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Date Deposited:	30 Jul 2024 07:05
FoR Codes:	30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3004 Crop and pasture production > 300401 Agrochemicals and biocides (incl. application) @ 100%
SEO Codes:	26 PLANT PRODUCTION AND PLANT PRIMARY PRODUCTS > 2699 Other plant production and plant primary products > 269903 Plant product traceability and quality assurance (excl. forest products) @ 100%
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