Faecal virome of the Australian grey-headed flying fox from urban/ suburban environments contains novel coronaviruses, retroviruses and sapoviruses
Van Brussel, Kate, Mahar, Jackie E., Ortiz-Baez, Ayda Susana, Carrai, Maura, Spielman, Derek, Boardman, Wayne S.J., Baker, Michelle L., Beatty, Julia A., Geoghegan, Jemma L., Barrs, Vanessa R., and Holmes, Edward C. (2022) Faecal virome of the Australian grey-headed flying fox from urban/ suburban environments contains novel coronaviruses, retroviruses and sapoviruses. Virology, 576. pp. 42-51.
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Abstract
Bats are important reservoirs for viruses of public health and veterinary concern. Virus studies in Australian bats usually target the families Paramyxoviridae, Coronaviridae and Rhabdoviridae, with little known about their overall virome composition. We used metatranscriptomic sequencing to characterise the faecal virome of greyheaded flying foxes from three colonies in urban/suburban locations from two Australian states. We identified viruses from three mammalian-infecting (Coronaviridae, Caliciviridae, Retroviridae) and one possible mammalianinfecting (Birnaviridae) family. Of particular interest were a novel bat betacoronavirus (subgenus Nobecovirus) and a novel bat sapovirus (Caliciviridae), the first identified in Australian bats, as well as a potentially exogenous retrovirus. The novel betacoronavirus was detected in two sampling locations 1375 km apart and falls in a viral lineage likely with a long association with bats. This study highlights the utility of unbiased sequencing of faecal samples for identifying novel viruses and revealing broad-scale patterns of virus ecology and evolution.
| Item ID: | 77346 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 1096-0341 |
| Copyright Information: | © 2022 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Funders: | Australian Research Council (ARC) |
| Projects and Grants: | ARC FL170100022 |
| Date Deposited: | 30 Jan 2023 23:37 |
| FoR Codes: | 31 BIOLOGICAL SCIENCES > 3107 Microbiology > 310706 Virology @ 100% |
| SEO Codes: | 18 ENVIRONMENTAL MANAGEMENT > 1806 Terrestrial systems and management > 180606 Terrestrial biodiversity @ 100% |
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