Yeshi, Karma, and Wangchuk, Phurpa (2023) Aconitum napellus (Monkshood). In: Husen, Azamal, (ed.) Exploring Poisonous Plants: Medicinal Values, Toxicity Responses, and Therapeutic Uses. CRC Press, Boca Raton, Florida, USA, pp. 101-112.

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Abstract

Aconitum napellus L. is a perennial herb with attractive blue flowers, and it belongs to the Ranunculaceae family. A. napellus is European native species, and it is also reported in Asia and Oceania. A. napellus was traditionally well known for arrow-head poison for hunting and was often used to poison imprisoned criminals in Europe. The whole plant is associated with toxic and medicinal properties, and it is widely used in Chinese traditional medicine, Japanese herbal preparations, Indian Ayurvedic medicine, and European homoeopathic preparations. It is used for various diseases and ailments, including facial paralysis, musculoskeletal pains, inflammation, gout, pyrexia, pericarditis for sciatica, and rheumatism. The plant contains cardiotoxins, chiefly ‘aconitine’; thus, any plant parts should be appropriately detoxified prior to usage. A rigorous boiling for an extended period or treatment with cow or goat milk can help to reduce aconitine content. Numerous phytochemicals are isolated from different parts of A. napellus, and they are mostly diterpenoid alkaloids and flavonol glycosides. Isolated compounds and crude extracts have shown few promising biological activities demonstrating the potential application of A. napellus for antipyretic, antidiabetic, antioxidant, and neuroprotective therapeutic purposes.

Item ID:	77302
Item Type:	Book Chapter (Research - B1)
ISBN:	9781003308249
Related URLs:	Publisher
Copyright Information:	© 2023 Taylor & Francis Group, LLC.
Date Deposited:	25 Jan 2023 01:02
FoR Codes:	34 CHEMICAL SCIENCES > 3405 Organic chemistry > 340502 Natural products and bioactive compounds @ 50% 34 CHEMICAL SCIENCES > 3404 Medicinal and biomolecular chemistry > 340401 Biologically active molecules @ 50%
SEO Codes:	20 HEALTH > 2004 Public health (excl. specific population health) > 200405 Food safety @ 40% 20 HEALTH > 2004 Public health (excl. specific population health) > 200412 Preventive medicine @ 20% 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280105 Expanding knowledge in the chemical sciences @ 40%
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