Jamtsho, Tenzin, Ugyen, and Wangchuk, Phurpa (2023) Datura stramonium (Thorn Apple or Devil’s Trumpet). In: Husen, Azamal, (ed.) Exploring Poisonous Plants: Medicinal Values, Toxicity Responses, and Therapeutic Uses. CRC Press, Boca Raton, Florida, USA, pp. 219-240.

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Abstract

Datura stramonium L. is a bushy annual herb belonging to the family Solanaceae. It is known by many common names, but the popular ones are thornapple, moonflower, hell’s bells, devil’s trumpet, and evil seeds. The plant is distributed worldwide, and it is found as a weed in garbage dumps, livestock enclosures, and wastelands. It is accredited with both toxic and medicinal properties. All plant parts are toxic if ingested and smoked, often resulting in delirium, hallucination, photophobia, hyperthermia, neurotoxicity, and severe mydriasis. Toxin concentration varies by parts, age, habitat, and local climate. Traditionally, the plant is used for skin disorders, inflammation, toothache, cough, fever, bronchitis, convulsion, asthma, burn, ulcer, wound, rheumatism, sciatica, and gout. The plant contains several phytochemicals, including tropane alkaloids, flavonoids, phenolic compounds, carbohydrates, cardiac glycosides, tannins, and amino acids. Tropane alkaloids such as atropine, scopolamine, and hyoscyamine are attributed to plants’ toxicity. Pharmacologically, the plant exhibits antifungal, antiasthmatic, larvicidal, antibacterial, anti-inflammatory, antioxidant, antispasmodic, anti-rheumatoid, anti-ulcer, and antinociceptive activities. This chapter will describe the traditional global uses of a plant and the current status of its toxicological, pharmacological, and phytochemical profiles.

Item ID:	77301
Item Type:	Book Chapter (Research - B1)
ISBN:	9781003308249
Keywords:	Datura, phytochemistry, toxicology, pharmacology
Related URLs:	https://www.taylorfrancis.com/chapters/e...
Copyright Information:	© 2023 Taylor & Francis Group, LLC.
Date Deposited:	25 Jan 2023 00:46
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3214 Pharmacology and pharmaceutical sciences > 321407 Toxicology (incl. clinical toxicology) @ 50% 34 CHEMICAL SCIENCES > 3405 Organic chemistry > 340502 Natural products and bioactive compounds @ 50%
SEO Codes:	28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280105 Expanding knowledge in the chemical sciences @ 50% 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280103 Expanding knowledge in the biomedical and clinical sciences @ 50%
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