Poly(2-oxazolines) in biological and biomedical application contexts

Adams, Nico, and Schubert, Ulrich S. (2007) Poly(2-oxazolines) in biological and biomedical application contexts. Advanced Drug Delivery Reviews, 59. pp. 1504-1520.

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Abstract

Polyoxazolines of various architectures and chemical functionalities can be prepared in a living and therefore controlled manner via cationic ring-opening polymerisation. They have found widespread applications, ranging from coatings to pigment dispersants. Furthermore, several polyoxazolines are water-soluble or amphiphilic and relatively non-toxic, which makes them interesting as biomaterials.

This paper reviews the development of polyoxazoline-based polymers in biological and biomedical application contexts since the beginning of the millennium. This includes nanoscalar systems such as membranes and nanoparticles, drug and gene delivery applications, as well as stimuli-responsive systems.

Item ID: 74844
Item Type: Article (Research - C1)
ISSN: 1872-8294
Keywords: Polyoxazoline; Biomaterials; Self-assembly; Drug delivery; Gene delivery; Stimuli-responsive polymers
Copyright Information: © 2007 Published by Elsevier B.V.
Date Deposited: 21 Mar 2024 01:51
FoR Codes: 34 CHEMICAL SCIENCES > 3403 Macromolecular and materials chemistry > 340302 Macromolecular materials @ 100%
SEO Codes: 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280105 Expanding knowledge in the chemical sciences @ 100%
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