de Matos, Paula, Adams, Nico, Hastings, Janna, Moreno, Pablo, and Steinbeck, Christoph (2011) A Database for Chemical Proteomics: ChEBI. In: Drewes, Gerard, and Bantscheff, Marcus, (eds.) Chemical Proteomics: methods and protocols. Methods in Molecular Biology, 803 . Springer, New York, NY, USA, pp. 273-296.

PDF (Published Version) - Published Version Restricted to Repository staff only

Abstract

Chemical proteomics is concerned with the identification of protein targets interacting with small molecules. Hence, the availability of a high quality and free resource storing small molecules is essential for the future development of the field. The Chemical Entities of Biological Interest (ChEBI) database is one such database. The scope of ChEBI includes any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity. These entities in question are either products of nature or synthetic products used to intervene in the processes of living organisms. In addition, ChEBI contains a chemical ontology which relates the small molecules with each other thereby making it easier for users to discover data. The ontology also describes the biological roles that the small molecules are active in. The ChEBI database also provides a central reference point in which to access a variety of bioinformatics data points such as pathways and their biochemical reactions; expression data; protein sequence and structures.

Item ID:	74395
Item Type:	Book Chapter (Scholarly Work)
ISSN:	1064-3745
Copyright Information:	© Springer Science+Business Media, LLC 2012
Date Deposited:	19 Nov 2024 03:17
FoR Codes:	34 CHEMICAL SCIENCES > 3407 Theoretical and computational chemistry > 340799 Theoretical and computational chemistry not elsewhere classified @ 50% 34 CHEMICAL SCIENCES > 3404 Medicinal and biomolecular chemistry > 340404 Cheminformatics and quantitative structure-activity relationships @ 50%
SEO Codes:	28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280105 Expanding knowledge in the chemical sciences @ 50% 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280102 Expanding knowledge in the biological sciences @ 50%
Downloads:	Total: 2 Last 12 Months: 2
	More Statistics