Vera, Julio, Kwon, Taesoo, Schmitz, Ulf, Kolch, Walter, and Wolkenhauer, Olaf (2009) Exploration of homodimer receptor: homodimer protein interactions. International Journal of Bioinformatics Research and Applications, 5 (4). p. 447.

PDF (Published Version) - Published Version Restricted to Repository staff only

Abstract

Homodimerisation is producing a protein?protein complex composed of two identical molecules. Dimerisation is a phenomenon often occurring in the regulation of biochemical systems like signal transduction pathways. We investigated whether the existence of a homodimer-activated receptor and the activation of homodimer transducers correspond to a more general pattern in cell signalling. We developed a workflow to merge data from the Gene Ontology and the BIND database to produce a list of interactions between homodimer receptors and homodimer proteins. Finally, we found a prevalence of homodimer-homodimer interactions in signalling systems in human cells.

Item ID:	69028
Item Type:	Article (Research - C1)
ISSN:	1744-5493
Copyright Information:	Copyright © 2009 Inderscience Enterprises Ltd.
Date Deposited:	19 Nov 2024 02:24
FoR Codes:	31 BIOLOGICAL SCIENCES > 3102 Bioinformatics and computational biology > 310205 Proteomics and metabolomics @ 100%
SEO Codes:	28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280102 Expanding knowledge in the biological sciences @ 100%
Downloads:	Total: 1
	More Statistics