IgE-mediated fish allergy in children

Buyuktiryaki, Betul, Masini, Marzio, Mori, Francesca, Barni, Simona, Liccioli, Giulia, Sarti, Lucrezia, Lordi, Lorenzo, Giovannini, Mattia, Toit, George Du, Lopata, Andreas Ludwig, and Marques-Mejias, Maria Andreina (2021) IgE-mediated fish allergy in children. Medicina, 57 (1). 76.

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DOI: 10.3390/medicina57010076

View at Publisher Website: https://doi.org/10.3390/medicina57010076

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Abstract

Abstract: Fish allergy constitutes a severe problem worldwide. Its prevalence has been calculated as high as 7% in paediatric populations, and in many cases, it persists into adulthood with life-threatening signs and symptoms. The following review focuses on the epidemiology of Immunoglobulin E (IgE)-mediated fish allergy, its pathogenesis, clinical manifestations, and a thorough approach to diagnosis and management in the paediatric population. The traditional approach for managing fish allergy is avoidance and rescue medication for accidental exposures. Food avoidance poses many obstacles and is not easily maintained. In the specific case of fish, food is also not the only source of allergens; aerosolisation of fish proteins when cooking is a common source of highly allergenic parvalbumin, and elimination diets cannot prevent these contacts. Novel management approaches based on immunomodulation are a promising strategy for the future of these patients.


Item ID:	65781
Item Type:	Article (Research - C1)
ISSN:	1648-9144
Copyright Information:	Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Date Deposited:	09 Feb 2021 02:12
FoR Codes:	46 INFORMATION AND COMPUTING SCIENCES > 4606 Distributed computing and systems software > 460606 Energy-efficient computing @ 50% 32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320401 Allergy @ 50%
SEO Codes:	92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 80% 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920406 Food Safety @ 20%
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