The therapeutic potential of ketogenic diet throughout life: focus on metabolic, neurodevelopmental and neurodegenerative disorders

Kraeuter, Ann-Katrin, Guest, Paul C., and Sarnyai, Zoltan (2019) The therapeutic potential of ketogenic diet throughout life: focus on metabolic, neurodevelopmental and neurodegenerative disorders. In: Guest, Paul C., (ed.) Reviews on Biomarker Studies in Aging and Anti-Aging Research. Advances in Experimental Medicine and Biology (1178). Springer, Cham, Switzerland, pp. 77-101.

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Abstract

This chapter reviews the efficacy of the ketogenic diet in a variety of neurodegenerative, neurodevelopmental and metabolic conditions throughout different stages of life. It describes conditions affecting children, metabolic disorders in adults and disorderrs affecting the elderly. We have focused on application of the ketogenic diet in clinical studies and in preclinical models and discuss the benefits and negative aspects of the diet. Finally, we highlight the need for further research in this area with a view of discovering novel mechanistic targets of the ketogenic diet, as a means of maximising the potential benefits/risks ratio.

Item ID: 61936
Item Type: Book Chapter (Research - B1)
ISSN: 2214-8019
Keywords: Biomarker, Disease, Drug development, Drug target, Ketogenic diet, Life stages
Copyright Information: © 2019, Springer Nature Switzerland AG.
Date Deposited: 10 Jun 2020 06:35
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1111 Nutrition and Dietetics > 111101 Clinical and Sports Nutrition @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1111 Nutrition and Dietetics > 111102 Dietetics and Nutrigenomics @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970111 Expanding Knowledge in the Medical and Health Sciences @ 100%
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