The pathology of systemic iridoviral disease in fish

Gibson-Kueh, S., Netto, P., Ngoh-Lim, G. H., Chang, S. F., Ho, L. L., Qin, Q. W., Chua, F. H. C., Ng, M. L., and Ferguson, H. W. (2003) The pathology of systemic iridoviral disease in fish. Journal of Comparative Pathology, 129 (2-3). pp. 111-119.

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Abstract

Iridoviruses have been associated with severe disease and economic loss in farmed food fish and ornamental fish, with mortality often reported to reach 50% or more. In the present study, three tropical marine food fish species and four tropical freshwater ornamental fish species with systemic iridovirus infections were examined histopathologically and ultrastructurally. Light microscopy consistently revealed pale to intensely basophilic hypertrophied virus-infected cells in spleen, kidney and intestine from all seven species. Ultrastructural examination showed changes in the vascular endothelium overlying hypertrophied virus-infected cells suggestive of pressure necrosis. Viral isolation was improved by the use of fibroblastic cell lines. This, together with the sub-endothelial location of infected cells in all infected species examined, suggests that systemic iridoviruses are mesotheliotropic. © 2003 Elsevier Ltd. All rights reserved.

Item ID: 59129
Item Type: Article (Research - C1)
ISSN: 1532-3129
Keywords: Fish, Iridovirus, Lymphocystis diseae, Systemic iridoviral disease, Viral infection
Date Deposited: 27 Nov 2019 01:36
FoR Codes: 07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070703 Veterinary Diagnosis and Diagnostics @ 25%
07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070709 Veterinary Pathology @ 50%
07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070712 Veterinary Virology @ 25%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences @ 50%
97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 50%
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