The genome sequence of Taurine cattle: a window to ruminant biology and evolution

The Bovine Genome Sequencing and Analysis Consortium, , Elsik, Christine G., Tellam, Ross L., and Worley, Kim C. (2009) The genome sequence of Taurine cattle: a window to ruminant biology and evolution. Science, 324 (5926). pp. 522-528.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: https://doi.org/10.1126/science.1169588
 
3


Abstract

To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.

Item ID: 55669
Item Type: Article (Research - C1)
ISSN: 1095-9203
Copyright Information: Copyright 2017 © The Authors, some rights reserved.
Additional Information:

Ashley Waardenberg is part of The Bovine Genome Sequencing and Analysis Consortium. All collaborators are listed at the end of the article.

Date Deposited: 23 Oct 2018 03:40
FoR Codes: 06 BIOLOGICAL SCIENCES > 0604 Genetics > 060407 Genome Structure and Regulation @ 80%
07 AGRICULTURAL AND VETERINARY SCIENCES > 0701 Agriculture, Land and Farm Management > 070199 Agriculture, Land and Farm Management not elsewhere classified @ 20%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100%
Downloads: Total: 3
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page