From fish to frogs and beyond: impact and host range of emergent ranaviruses

Price, Stephen J., Ariel, Ellen, Maclaine, Alicia, Rosa, Goncalo M., Gray, Matthew J., Brunner, Jesse F., and Garner, Trenton W.J. (2017) From fish to frogs and beyond: impact and host range of emergent ranaviruses. Virology, 511. pp. 272-279.

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Abstract

Ranaviruses are pathogens of ectothermic vertebrates, including amphibians. We reviewed patterns of host range and virulence of ranaviruses in the context of virus genotype and postulate that patterns reflect significant variation in the historical and current host range of three groups of Ranavirus: FV3-like, CMTV-like and ATVlike ranaviruses. Our synthesis supports previous hypotheses about host range and jumps: FV3s are amphibian specialists, while ATVs are predominantly fish specialists that switched once to caudate amphibians. The most recent common ancestor of CMTV-like ranaviruses and FV3-like forms appears to have infected amphibians but CMTV-like ranaviruses may circulate in both amphibian and fish communities independently. While these hypotheses are speculative, we hope that ongoing efforts to describe ranavirus genetics, increased surveillance of host species and targeted experimental assays of susceptibility to infection and/or disease will facilitate better tests of the importance of hypothetical evolutionary drivers of ranavirus virulence and host range.

Item ID: 53264
Item Type: Article (Research - C1)
ISSN: 1089-862X
Keywords: host range, Ranavirus, emerging pathogen, disease
Copyright Information: © 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/).
Funders: National Environmental Research Council (NERC)
Projects and Grants: NERC grant NE/M000338/1, NERC grant NE/M000591/1, NERC grant NE/M00080X/1
Date Deposited: 23 Apr 2018 03:54
FoR Codes: 30 AGRICULTURAL, VETERINARY AND FOOD SCIENCES > 3009 Veterinary sciences > 300905 Veterinary epidemiology @ 100%
SEO Codes: 96 ENVIRONMENT > 9604 Control of Pests, Diseases and Exotic Species > 960404 Control of Animal Pests, Diseases and Exotic Species in Forest and Woodlands Environments @ 30%
96 ENVIRONMENT > 9604 Control of Pests, Diseases and Exotic Species > 960406 Control of Pests, Diseases and Exotic Species in Fresh, Ground and Surface Water Environments @ 30%
83 ANIMAL PRODUCTION AND ANIMAL PRIMARY PRODUCTS > 8301 Fisheries - Aquaculture > 830102 Aquaculture Fin Fish (excl. Tuna) @ 40%
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