Pyrethroid susceptibility has been maintained in the dengue vector, Aedes aegypti (Diptera: Culicidae), in Queensland, Australia

Endersby-Harshman, Nancy M., Wuliandari, Juli Rochmijati, Harshman, Lawrence G., Frohn, Verena, Johnson, Brian J., Ritchie, Scott A., and Hoffmann, Ary A. (2017) Pyrethroid susceptibility has been maintained in the dengue vector, Aedes aegypti (Diptera: Culicidae), in Queensland, Australia. Journal of Medical Entomology, 54 (6). pp. 1649-1658.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: https://doi.org/10.1093/jme/tjx145
8


Abstract

Although pesticide resistance is common in insect vectors of human diseases, the evolution of resistance might be delayed if management practices are adopted that limit selection of resistance alleles. Outbreaks of dengue fever have occurred in Queensland, Australia, since the late 1800s, leading to ongoing attempts to control the mosquito vector, Aedes aegypti (L.). Since the 1990s, pyrethroid insecticides have been used for this purpose, but have been applied in a strategic manner with a variety of delivery methods including indoor residual spraying, lethal ovitraps, and use of insect growth regulators as larvicides. Separate selection experiments on mosquitoes from Queensland using Type I and Type II pyrethroids did not produce resistant lines of Ae. aegypti, and bioassays of field material from Queensland showed only weak tolerance in comparison with a susceptible line. There was no evidence of knockdown resistance (kdr) mutations in Ae. aegypti from Queensland, in stark contrast to the situation in nearby southeast Asia. We suspect that careful management of pyrethroid insecticide use combined with surveillance and interception of exotic incursions has helped to maintain pyrethroid (and particularly kdr-based) susceptibility in Ae. aegypti in Australia.

Item ID: 52400
Item Type: Article (Research - C1)
ISSN: 1938-2928
Keywords: insecticide resistance, sodium channel, mosquito
Funders: National Health and Medical Research Council (NHMRC)
Projects and Grants: NHMRC 1037003, NHMRC fellowship number 1044698
Date Deposited: 07 Feb 2018 07:39
FoR Codes: 06 BIOLOGICAL SCIENCES > 0608 Zoology > 060808 Invertebrate Biology @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100%
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page