Gas transport and exchange: interaction between O2 and CO2 exchange

Brauner, C.J., and Rummer, J.L. (2011) Gas transport and exchange: interaction between O2 and CO2 exchange. In: Farrell, Anthony P., (ed.) Encyclopedia of Fish Physiology: from genome to environment. Elsevier, London, UK, pp. 916-920.

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The interaction between O2 and CO2 in the general circulation of fish exists at the level of hemoglobin within the red blood cell, and is determined largely by the magnitude of the Bohr and Haldane effects. Assuming steady-state conditions, a Bohr–Haldane coefficient of 0.35–0.5 (0.5 × the respiratory quotient, RQ) is optimal for tissue O2 delivery (excluding the swimbladder and eye), and greater values may be important for CO2 excretion and acid–base homeostasis. Many teleosts possess a nonlinear Bohr–Haldane coefficient over the oxygen-equilibrium curve (OEC), which alters the nature of the interaction when different regions of the OEC are used for gas exchange. Recent in vivo experiments indicate that Bohr–Haldane coefficients close to RQ (typically 0.7–1.0) may play an important role in facilitating tissue O2 delivery in vivo likely due to the existence of large disequilibrium states in the blood.

Item ID: 45321
Item Type: Book Chapter (Research - B1)
ISBN: 978-0-08-092323-9
Date Deposited: 31 Aug 2016 03:19
FoR Codes: 06 BIOLOGICAL SCIENCES > 0608 Zoology > 060809 Vertebrate Biology @ 50%
06 BIOLOGICAL SCIENCES > 0606 Physiology > 060602 Animal Physiology - Cell @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100%
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