Thermotolerance of L3Ostertagia (Teladorsagia) circumcincta and some of its enzymes

Walker, Lisa R., Simcock, David C., Neale, Jennifer D., Simpson, Heather V., Brown, Simon, UNSPECIFIED, and UNSPECIFIED (2007) Thermotolerance of L3Ostertagia (Teladorsagia) circumcincta and some of its enzymes. Veterinary Parasitology, 146 (1-2). pp. 77-82.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website:


Parasitic nematodes of ruminants can be expected to experience temperatures in excess of 40 °C in faeces on pasture and, perhaps, in the host. L3Ostertagia (Teladorsagia) circumcincta survived for at least 90 min at 45 °C in vitro in water, but the larvae were inactivated rapidly by only slightly higher temperatures. The glycolytic enzymes hexokinase and pyruvate kinase were inactivated in a similar temperature range, whereas malate dehydrogenase maintained its activity at temperatures in excess of 50 °C. These data imply that the loss of glycolytic activity might explain the loss of larval motility at temperatures between 45 °C and 50 °C.

Item ID: 36373
Item Type: Article (Research - C1)
ISSN: 1873-2550
Keywords: thermotolerance; parasite (Ostertagia circumincta); parasite (Teladorsagia circumcincta); enzyme
Funders: Meat and Wool Innovation Ltd, AGMARDT
Date Deposited: 25 Sep 2015 01:12
FoR Codes: 06 BIOLOGICAL SCIENCES > 0601 Biochemistry and Cell Biology > 060107 Enzymes @ 50%
06 BIOLOGICAL SCIENCES > 0606 Physiology > 060604 Comparative Physiology @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 50%
97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 50%
Downloads: Total: 1
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page