Cytokines, nitric oxide, heat shock proteins and virulence in toxoplasma

Miller, C.M.D., Smith, N.C., and Johnson, A.M. (1999) Cytokines, nitric oxide, heat shock proteins and virulence in toxoplasma. Parasitology Today, 15 (10). pp. 418-422.

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Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.

Item ID: 34606
Item Type: Article (Commentary)
ISSN: 1471-5007
Keywords: cytokines; nitric oxide; HSP; virulence; Toxoplasma
Funders: Australian Research Council (ARC), University of Technology, Sydney
Date Deposited: 26 Aug 2014 05:32
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110707 Innate Immunity @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 50%
97 EXPANDING KNOWLEDGE > 970111 Expanding Knowledge in the Medical and Health Sciences @ 50%
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