Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production

Adarme-Vega, T. Catalina, Lim, David K.Y., Timmins, Matthew, Vernen, Felicitas, Li, Yan, and Schenk, Peer M. (2012) Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production. Microbial Cell Factories, 11 (July). 96. pp. 1-10.

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Abstract

Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) provide significant health benefits and this has led to an increased consumption as dietary supplements. Omega-3 fatty acids EPA and DHA are found in animals, transgenic plants, fungi and many microorganisms but are typically extracted from fatty fish, putting additional pressures on global fish stocks. As primary producers, many marine microalgae are rich in EPA (C20:5) and DHA (C22:6) and present a promising source of omega-3 fatty acids. Several heterotrophic microalgae have been used as biofactories for omega-3 fatty acids commercially, but a strong interest in autotrophic microalgae has emerged in recent years as microalgae are being developed as biofuel crops. This paper provides an overview of microalgal biotechnology and production platforms for the development of omega-3 fatty acids EPA and DHA. It refers to implications in current biotechnological uses of microalgae as aquaculture feed and future biofuel crops and explores potential applications of metabolic engineering and selective breeding to accumulate large amounts of omega-3 fatty acids in autotrophic microalgae.

Item ID: 28112
Item Type: Article (Research - C1)
ISSN: 1475-2859
Keywords: docosahexaenoic acid, DHA, eicosapentaenoic acid, EPA, microalgae, omega-3 fatty acids, polyunsaturated fatty acids
Additional Information:

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Funders: Australian Research Council (ARC), Queensland Sea Scallops
Date Deposited: 24 Jul 2013 00:50
FoR Codes: 06 BIOLOGICAL SCIENCES > 0607 Plant Biology > 060701 Phycology (incl Marine Grasses) @ 50%
10 TECHNOLOGY > 1003 Industrial Biotechnology > 100302 Bioprocessing, Bioproduction and Bioproducts @ 50%
SEO Codes: 85 ENERGY > 8505 Renewable Energy > 850501 Biofuel (Biomass) Energy @ 50%
97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 50%
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