Improved molecular-diagnostic tools for human hookworms

Gasser, Robin B., Cantacessi, Cinzia, and Campbell, Bronwyn E. (2009) Improved molecular-diagnostic tools for human hookworms. Expert Review of Molecular Diagnostics, 9 (1 ). pp. 17-21.

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Abstract

Blood-feeding hookworms are parasitic roundworms (i.e., nematodes) of major socioeconomic importance, affecting millions of people worldwide. Despite their impact on human health, little attention has been paid to improving practical methods of diagnosis. The genetic characterization of hookworms and specific diagnosis of their infections are central to elucidating the ecology and epidemiology of these parasites as well as the control of the disease they cause. Traditional coprodiagnostic methods have major limitations. This article summarizes progress in the development of molecular-analytical and -diagnostic tools, and discusses the need to establish practical 'laboratory' and 'field' assays for use in integrated hookworm prevention and control programs.

Item ID: 26535
Item Type: Article (Research - C1)
ISSN: 1744-8352
Keywords: parasitic nematodes; molecular diagnostics; public health; neglected diseases
Date Deposited: 03 May 2013 05:47
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology @ 60%
11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111799 Public Health and Health Services not elsewhere classified @ 30%
06 BIOLOGICAL SCIENCES > 0604 Genetics > 060499 Genetics not elsewhere classified @ 10%
SEO Codes: 86 MANUFACTURING > 8608 Human Pharmaceutical Products > 860802 Human Diagnostics @ 80%
92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920499 Public Health (excl. Specific Population Health) not elsewhere classified @ 20%
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