Presence of three distinct genotypes within the Paragonimus westermani complex in northeastern India

Devi, K. Rekha, Narain, Kanwar, Mahanta, Jagadish, Nirmolia, Tulika, Blair, David, Saikia, Sidhartha P., and Agatsuma, Takeshi (2013) Presence of three distinct genotypes within the Paragonimus westermani complex in northeastern India. Parasitology, 140 (1). pp. 76-86.

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The name Paragonimus westermani (Kerbert, 1878) is commonly applied to members of a species complex that includes the well-known Asian lung fluke of medical and veterinary importance. Unambiguous molecular and morphological evidence showing the presence of a member of the complex in India has recently been published. In the present study we report the occurrence of 2 more members of the P. westermani complex in northeastern (NE) India. Surveys of the freshwater crabs Maydelliatelphusa lugubris in NE India revealed 2 morphologically distinct types of lung fluke metacercariae. Phylogenetic analyses, using DNA sequences from ITS2, 28S and cox1 gene regions indicate that these lung metacercariae belong to P. westermani complex. Type 1 metacercariae have a more basal position within the complex whereas type 2 metacercariae are closely related to the relatively derived forms of P. westermani from NE Asia (Japan, Korea, China) and Vietnam. A third type of metacercaria (type 3), detected in another crab host, Sartoriana spinigera in Assam, was phylogenetically close to P. siamensis, also a member of the P. westermani group. Molecular evidence has demonstrated the existence of 3 genotypes of lung flukes within the Paragonimus westermani complex in NE India. Two of these were previously unknown.

Item ID: 25085
Item Type: Article (Research - C1)
ISSN: 1469-8161
Keywords: Paragonimus westermani complex, lung flukes, India
Funders: Indian Council of Medical Research
Projects and Grants: 49/7/RMRC/07-NCD-II
Date Deposited: 20 Feb 2013 09:10
FoR Codes: 06 BIOLOGICAL SCIENCES > 0603 Evolutionary Biology > 060309 Phylogeny and Comparative Analysis @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920120 Zoonoses @ 100%
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