Irukandji syndrome, cause for troponin leak and stress cardiomyopathy

Tiong, Keith, Jin, Sang-Won, Seymour, Jamie, and Pereira, Peter (2008) Irukandji syndrome, cause for troponin leak and stress cardiomyopathy. Heart, Lung and Circulation, 17 (Supplement 3). 200. S84-S85.

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Introduction: Carukia Barseni (also know as Irukandji) is a type of box jelly fish unique to North Queensland. We present a case series of irukandji syndrome which presented to Cairns Base Hospital recently.

Method/Design: Consents were obtained from all subjects. Regular observations were performed, baseline electrocardiograms, serial serum troponins and differential white cell counts. Serial transthoracic echocardiograms were performed in cases of positive troponins.

Results: Four cases with positive troponins were identified. The age group range from 14-40 years of age, median age 24.3 are males and 1 female. These cases presents within 14h of contact. Two cases were documented with persistent hypertension, one with persistent tachycardia, three with heart rate variabilties. Only two electrocardiograms were abnormal. Intravenous magnesium and/or nitrates infusion were given in three of the cases. The eosinophils counts were normal in all cases. These were associated with a rise in the level of serum troponins. Serial transthoracic echocardiograms were performed to identify the cause of troponin rise which included regional wall motion abnormalities, left ventricular function by Simpson's method and tissue doppler imaging. There were only one case of impaired left ventricular function, identified as a case of stress cardiomyopathy.

Conclusion: Irukandji syndrome is associated with sudden catecholamines release. The sympathetic overdrive is a cause of transient troponin rise, which precipitates stress cardiomyopathy.

Item ID: 24924
Item Type: Article (Abstract)
ISSN: 1444-2892
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From: Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting

Date Deposited: 23 Oct 2013 21:59
FoR Codes: 06 BIOLOGICAL SCIENCES > 0606 Physiology > 060699 Physiology not elsewhere classified @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100%
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