ESI FTICR-MS analysis of larvae from the marine sponge Luffariella variabilis
Motti, Cherie A., Ettinger-Epstein, Piers, Willis, Richard H., and Tapiolas, Dianne M. (2010) ESI FTICR-MS analysis of larvae from the marine sponge Luffariella variabilis. Marine Drugs, 8 (1). pp. 190-199.
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Abstract
The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.
| Item ID: | 16954 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 1660-3397 |
| Keywords: | Luffariella variabilis; manoalide monoacetate; larvae; ESI FTICR-MS; constitutive defence |
| Date Deposited: | 16 May 2011 01:01 |
| FoR Codes: | 06 BIOLOGICAL SCIENCES > 0601 Biochemistry and Cell Biology > 060101 Analytical Biochemistry @ 100% |
| SEO Codes: | 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100% |
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