First report of saxitoxin in octopi

Robertson, Alison, Stirling, David, Robillot, Cedric, Llewellyn, Lyndon, and Negri, Andrew (2004) First report of saxitoxin in octopi. Toxicon, 44 (7). pp. 765-771.

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Abstract

We report for the first time, the presence of saxitoxin (STX) in a common cephalopod, Octopus (Abdopus) sp. 5, collected from Cooke Point on the northern coastline of Western Australia. Sodium channel and saxiphilin based radio-receptor assays detected saxitoxin-like binding in octopi extracts. Further analysis by liquid chromatography-fluorescence detection (LC-FLD) identified STX as the major contributing toxin in these samples. The presence of STX was confirmed by LC-mass spectrometry and comparison of fragmentation patterns with an authentic STX standard. LC-FLD quantitation and conversion of the Octopus sp. 5 extracts revealed toxin concentrations as high as 246 μg STX/100 g tissue, more than three times the US, European and Australian regulatory limit for human consumption of shellfish of 80 μg STX/100 g tissue. There was no evidence of tetrodotoxin or other paralytic shellfish toxin derivatives. This level and distribution of STX in octopi poses a potential public health risk, particularly when routine toxin screening of wild catch is not regulated.

Item ID: 13950
Item Type: Article (Refereed Research - C1)
Keywords: Octupus; paralytic shellfish toxin; saxitoxin; shellfish poisoning; tetrodotoxin
ISSN: 0041-0101
Date Deposited: 11 Nov 2010 01:32
FoR Codes: 06 BIOLOGICAL SCIENCES > 0601 Biochemistry and Cell Biology > 060199 Biochemistry and Cell Biology not elsewhere classified @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100%
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