Performance of a GPU- and time-efficient pseudo-3D network for magnetic resonance image super-resolution and motion artifact reduction

Li, Hao, Liu, Jianan, Schell, Marianne, Huang, Tao, Lauer, Arne, Schregel, Katharina, Jesser, Jessica, Vollherbst, Dominik F., Bendszus, Martin, Heiland, Sabine, and Hilgenfeld, Tim (2026) Performance of a GPU- and time-efficient pseudo-3D network for magnetic resonance image super-resolution and motion artifact reduction. Scientific Reports, 16. 9654.

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Abstract

Minimizing acquisition time and motion-artifacts remains challenging in magnetic resonance imaging (MRI) with demands on high-resolution images for accurate diagnosis and treatment. Deep learning-based image restoration offers promising solution by generating high-resolution and artifact-free MR images from low-resolution or motion-corrupted data. To facilitate practical deployment in clinical workflows, this study presents a time-/GPU-efficient framework using 2D network (TS-RCAN) for pseudo-3D MRI super-resolution reconstruction (SRR) and motion-artifact reduction (MAR). Optimal down-sampling factors were identified to balance SRR accuracy and acquisition time. MAR training used a standardized method to induce controllable motion-artifacts of varying severity. Network performance was benchmarked against state-of-the-art 3D networks. Results showed the down-sampling factor for acceleration and for acceleration achieved optimal SRR performance. TS-RCAN outperformed most 3D networks by > 0.01/1.5 dB in SSIM/PSNR while reducing GPU load and inference time by up to 90%. For MAR, TS-RCAN exceeded UNet by up to 0.014/1.48 dB in SSIM/PSNR. Additionally, uncertainty estimation correlated with image quality metrics, enabling accuracy prediction without ground truth. TS-RCAN provides an efficient, accurate framework for SRR and MAR with practical relevance to clinical MRI, and offers a flexible basis for future extension to other imaging contrasts and pathological cases.

Item ID: 91430
Item Type: Article (Research - C1)
ISSN: 2045-2322
Keywords: 3D motion artifact reduction, 3D super-resolution reconstruction, GPU and time efficiency, Magnetic resonance imaging, Uncertainty for image quality estimation
Copyright Information: © The Author(s) 2026. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Date Deposited: 24 Aug 2026 03:38
FoR Codes: 40 ENGINEERING > 4003 Biomedical engineering > 400304 Biomedical imaging @ 50%
46 INFORMATION AND COMPUTING SCIENCES > 4603 Computer vision and multimedia computation > 460306 Image processing @ 50%
SEO Codes: 28 EXPANDING KNOWLEDGE > 2801 Expanding knowledge > 280110 Expanding knowledge in engineering @ 100%
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